A5049614623- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Vascular Malformations Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced Neuroimaging Techniques and Applications
- Cerebrospinal fluid and hydrocephalus
- Multiple Sclerosis Research Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Fetal and Pediatric Neurological Disorders
- Moyamoya disease diagnosis and treatment
- Glioma Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Stroke Rehabilitation and Recovery
- Neurosurgical Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Functional Brain Connectivity Studies
- Radiomics and Machine Learning in Medical Imaging
- Radiation Dose and Imaging
- Venous Thromboembolism Diagnosis and Management
- Dementia and Cognitive Impairment Research
- Healthcare Systems and Practices
- Radiology practices and education
- Meningioma and schwannoma management
Inserm
2016-2025
Université de Lille
2016-2025
Centre National de la Recherche Scientifique
2021-2025
Centre Hospitalier Universitaire de Lille
2016-2025
Institut Pasteur de Lille
2021-2025
Centre de Recherche Jean Pierre Aubert
2020-2024
Centre Oscar Lambret
1994-2024
Lille Neurosciences & Cognition
2020-2024
Lille’s Cardiology Hospital
1987-2023
Health and Education Research Management and Epidemiologic Services (United States)
2023
Carotid stenting is less invasive than endarterectomy, but it unclear whether as safe in patients with symptomatic carotid-artery stenosis.We conducted a multicenter, randomized, noninferiority trial to compare endarterectomy carotid stenosis of at least 60%. The primary end point was the incidence any stroke or death within 30 days after treatment.The stopped prematurely inclusion 527 for reasons both safety and futility. 30-day 3.9% (95% confidence interval [CI], 2.0 7.2) 9.6% CI, 6.4...
Neurologic involvement occurs in approximately 20% of patients with primary Sjögren syndrome (SS). However, the diagnosis SS neurologic is sometimes difficult, and central nervous system (CNS) manifestations have been described rarely. We conducted current study to describe clinical laboratory features report their outcome. retrospectively studied 82 (65 women 17 men) associated SS, as defined by 2002 American-European criteria. The mean age at onset was 53 years. frequently preceded (81%...
The purpose of this study is to report our preliminary experience with the flow-diverter Silk stent for endovascular treatment intracranial aneurysms.This prospective was approved by authors' ethical committees. Twenty-nine patients 34 fusiform or wide-necked unruptured aneurysms were included and treated placement alone 2 physicians in 3 different centers. Technical issues, immediate findings, delayed complications, clinical follow-up, imaging follow-up at 6 months assessed.Endovascular...
<h3>SUMMARY:</h3> Coronavirus disease 2019 (COVID-19) is a viral infection caused by the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), which spreads rapidly from person to and manifests in most symptomatic patients as respiratory illness, similar prior SARS viruses. Neurologic manifestations of COVID-19 are uncommon; those so far reported include encephalopathy, stroke large-vessel occlusion, polyneuropathy. We report unique neurologic complication patient who had extensive...
Iron content is increased in the substantia nigra of persons with Parkinson's disease and may contribute to pathophysiology disorder. Early research suggests that iron chelator deferiprone can reduce nigrostriatal disease, but its effects on progression are unclear.
Purpose To assess the performance of a local open-source large language model (LLM) in various information extraction tasks from real-life emergency brain MRI reports. Materials and Methods All consecutive reports written 2022 French quaternary center were retrospectively reviewed. Two radiologists identified scans that performed department for headaches. Four scored reports' conclusions as either normal or abnormal. Abnormalities labeled headache-causing incidental. Vicuna (LMSYS Org), an...
Early noncontrast computed tomographic scans may visualize a hyperdense middle cerebral artery before the infarct becomes visible. This sign disappears within few days, corresponds to clot itself, and might be associated with poor prognosis. The aim of study was determine its prevalence, diagnostic value, relationship demographic data, ability separate embolic from nonembolic causes, short-term prognostic evolution over time, arterial occlusion on angiography.We performed this using 12 hours...
To determine lesion locations associated with the various types of aphasic disorders in patients stroke.The anatomy aphasia has been challenged by several recent studies. Discrepancies are likely to be due methodologic issues.We examined 107 a standardized battery and MRI. Three examiners blinded clinical data rated signal abnormalities 69 predetermined regions interest. The statistical procedure used classification tree testing, which selected each disorder.1) Nonfluent depended on presence...
Many clinical trials are currently being conducted to evaluate the ability of neuroprotectors and thrombolytic agents improve survival functional outcome after ischemic stroke. Such require early predictors disability for ethical methodological reasons. The aim study was determine which variables, those easily assessable during first 24 hours stroke onset, would be 8-day mortality rate 3-month outcome.One hundred fifty-two consecutive patients with an acute event were evaluated within...
Over a third of minor stroke patients experience post-stroke cognitive impairment (PSCI), but no validated tools exist to identify at-risk early. This study investigated whether disconnection features derived from infarcts and white matter hyperintensities (WMH) could serve as markers for short- long-term decline in first-ever ischemic patients. First-ever (NIHSS ≤ 7) were prospectively followed at 72-h, 6 months, 36 months with tests brain MRI. Infarct WMH volumes semi-automatically...
We attempted to evaluate the sensitivity of helical CT for diagnosis extracranial internal carotid artery (ICA) dissection.Sixteen consecutive patients with 18 angiographically confirmed ICA dissections were studied a protocol large-volume acquisition and thin axial slice reconstructions. A control group including normal atherosclerotic ICAs was formed comparison, blind interpretation images made by two observers. evaluated presence stenosis, eccentric lumen, mural thickening, aneurysm,...
To determine the possible role of Wallerian degeneration secondary to grey matter neuronal loss in pathogenesis "leuko-araiosis", computerised tomography (CT) brain was studied 98 normotensive and non diabetic subjects free cardiac diseases: 32 with Alzheimer's disease, 36 Parkinson's eight progressive supranuclear palsy, 22 controls. In leuko-araiosis scores were greater than control subjects. Leuko-araiosis more prominent anterior periventricular areas disease posterior disease. two...
Abstract Evidence for cortical sensory activation in the human fetus at beginning of third trimester pregnancy was provided a recent imaging study. Although hearing is functional before birth, it not clear whether recognition mother's voice learned utero or rapidly following delivery. We developed an original fMRI procedure that allows specific exploration fetal brain response to auditory stimuli. This provides first vivo evidence development maternal between 33 and 34 weeks gestation....
To compare magnetic resonance (MR) imaging features of multiple sclerosis (MS) lesions after the administration a gadolinium-based contrast agent and ultrasmall superparamagnetic iron oxide (USPIO) particles among clinical phenotypes MS over time.This study was approved by local ethics committee, written informed consent obtained from all patients. Twenty-four patients with (10 relapsing 14 progressive forms) underwent gadolinium- USPIO-enhanced MR examinations at baseline 6-month follow-up....
<h3>Objective:</h3> To evaluate the usefulness of punctate pattern (PP) for diagnosis and follow-up patients with progressive multifocal leukoencephalopathy (PML). <h3>Methods:</h3> A cohort 20 consecutive PML, related to natalizumab (NTZ) (n = 14) or not 6), underwent 3T MRI (147 examinations). was available at presymptomatic 9 patients), symptomatic 15), immune reconstitution inflammatory syndrome (IRIS), chronic stages 20). pathologic control group without PML 80), clinically definitive...