A5015914576- Schizophrenia research and treatment
- Functional Brain Connectivity Studies
- Hallucinations in medical conditions
- Psychosomatic Disorders and Their Treatments
- Neural dynamics and brain function
- Mental Health and Psychiatry
- Neuroscience and Music Perception
- Mental Health Research Topics
- Psychoanalysis and Psychopathology Research
- Neural and Behavioral Psychology Studies
- Child Nutrition and Feeding Issues
- Advanced Neuroimaging Techniques and Applications
- Transcranial Magnetic Stimulation Studies
- Attention Deficit Hyperactivity Disorder
- EEG and Brain-Computer Interfaces
- Maternal Mental Health During Pregnancy and Postpartum
- Bipolar Disorder and Treatment
- Psychedelics and Drug Studies
- Neurology and Historical Studies
- Electroconvulsive Therapy Studies
- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Autism Spectrum Disorder Research
- Diet and metabolism studies
- Pain Management and Placebo Effect
Hôpital Fontmaure
2016-2025
Université de Lille
2015-2024
Inserm
2013-2024
Centre Hospitalier Universitaire de Lille
2015-2024
Lille Neurosciences & Cognition
2020-2024
Institut Universitaire de France
2024
Institut de Biologie de l'École Normale Supérieure
2023-2024
Centre de Recherche Jean Pierre Aubert
2014-2023
Université Paris Sciences et Lettres
2017-2023
Laboratoire de Neurosciences Cognitives
2008-2023
Auditory verbal hallucinations (AVH) in patients with schizophrenia are associated abnormal hyperactivity the left temporo-parietal junction (TPJ) and connectivity between frontal temporal areas. Recent findings suggest that fronto-temporal transcranial Direct Current stimulation (tDCS) cathode placed over TPJ anode prefrontal cortex can alleviate treatment-resistant AVH schizophrenia. However, brain correlates of reduction unclear. Here, we investigated effect tDCS on resting-state...
A considerable number of recent experimental and computational studies suggest that subtle impairments excitatory to inhibitory balance or regulation are involved in many neurological psychiatric conditions. The current paper aims relate, specifically quantitatively, imbalance with psychotic symptoms schizophrenia. Considering the brain constructs hierarchical causal models external world, we show failure maintain results hallucinations as well formation subsequent consolidation delusional...
The pathophysiology of hallucinations remains mysterious. This research aims to specifically explore the interaction between and spontaneous resting-state activity. We used multimodal magnetic resonance imaging during occurrence in 20 drug-free adolescents with a "brief psychotic disorder." They were furthermore compared matched controls at rest or exteroceptive stimuli. Anatomical functional symptom-mapping demonstrated reduced cortical thickness increased blood oxygen level–dependent...
Abstract Schizophrenia (SCZ) is a complex mental disorder that may result in some combination of hallucinations, delusions and disorganized thinking. Here SCZ patients healthy controls (CTLs) report their level confidence on forced-choice task manipulated the strength sensory evidence prior information. Neither group’s responses can be explained by simple Bayesian inference. Rather, individual are best captured model with different degrees circular Circular inference refers to corruption...
BackgroundDisentangling psychopathological heterogeneity in schizophrenia is challenging, and previous results remain inconclusive. We employed advanced machine learning to identify a stable generalizable factorization of the Positive Negative Syndrome Scale used it subtypes as well their neurobiological differentiations.MethodsPositive data from Pharmacotherapy Monitoring Outcome Survey cohort (1545 patients; 586 followed up after 1.35 ± 0.70 years) were for factor structure by an...
The majority of patients with schizophrenia suffer from hallucinations. While the triple-network model, which includes default mode network (DMN), central executive (CEN) and salience (SAL), has recently been applied to schizophrenia, how this framework could explain emergence hallucinations remains unclear. Therefore, complementary brain regions that have linked hallucinations, such as left hippocampus, should also be considered added model. Accordingly, present study explored effective...
Introduction: Cognitive and functional compromise, as frequently observed in Alzheimer's disease (AD), hinders communication social interactions. One consequence of this hindrance may be a feeling loneliness. Moreover, emptiness boredom, isolation loneliness, thus compensated for by creating imagined stimuli. Conditions loneliness viewed potentially generating hallucinatory experiences. To assess assumption, the present study explored relationship between isolation, hallucinations sample 22...
Abstract Evidence for cortical sensory activation in the human fetus at beginning of third trimester pregnancy was provided a recent imaging study. Although hearing is functional before birth, it not clear whether recognition mother's voice learned utero or rapidly following delivery. We developed an original fMRI procedure that allows specific exploration fetal brain response to auditory stimuli. This provides first vivo evidence development maternal between 33 and 34 weeks gestation....
Background Patients with anorexia nervosa (AN) usually report feeling larger than they really are. This body overestimation appears to be related not only the patient's image but also an abnormal representation of in action. In previous work on a body-scaled anticipation task, anorexic patients judged that could pass through door-like aperture even when it was easily wide enough - suggesting involvement schema. present study, we sought establish whether this erroneous judgment about action...
Schizophrenia and depression are prevalent psychiatric disorders, but their underlying neural bases remains poorly understood. Neuroimaging evidence has pointed towards the relevance of functional connectivity aberrations in default mode network (DMN) hubs, dorso-medial prefrontal cortex precuneus, both commonalities differences resting state those two regions across disorders not been formally assessed. Here, we took a transdiagnostic approach to investigate 75 patients with schizophrenia...