A5100331894- Cervical Cancer and HPV Research
- Viral Infections and Immunology Research
- Hepatitis B Virus Studies
- Whipple's Disease and Interleukins
- Acute Ischemic Stroke Management
- Endometrial and Cervical Cancer Treatments
- Medical Research and Treatments
- Syphilis Diagnosis and Treatment
- Palliative Care and End-of-Life Issues
- Salivary Gland Tumors Diagnosis and Treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Multiple and Secondary Primary Cancers
- Immunodeficiency and Autoimmune Disorders
- Gastrointestinal motility and disorders
- Chronic Disease Management Strategies
- Epigenetics and DNA Methylation
- Cancer-related gene regulation
- Head and Neck Cancer Studies
- Cannabis and Cannabinoid Research
- T-cell and Retrovirus Studies
- Genetic factors in colorectal cancer
- Stroke Rehabilitation and Recovery
- Lymphoma Diagnosis and Treatment
- Respiratory viral infections research
- Animal Disease Management and Epidemiology
New York University
2025
Yantaishan Hospital
2023
State Key Laboratory of Oncology in South China
2021
Sun Yat-sen University
2016-2021
Sun Yat-sen University Cancer Center
2021
Second Affiliated Hospital of Xi'an Jiaotong University
2017-2019
Nanjing Drum Tower Hospital
2016-2019
Sun Yat-sen Memorial Hospital
2016
West China Hospital of Sichuan University
2009
Sichuan University
2009
Abstract Background The high cost and insufficient supply of human papillomavirus (HPV) vaccines have slowed the pace controlling cervical cancer. A phase III clinical trial was conducted to evaluate efficacy, safety, immunogenicity a novel Escherichia coli-produced bivalent HPV-16/18 vaccine. Methods multicenter, randomized, double-blind started on November 22, 2012 in China. In total, 7372 eligible women aged 18–45 years were age-stratified randomly assigned receive three doses test or...
Uptake of the human papillomavirus (HPV) vaccine is suboptimal globally. Effective interventions are needed to meet global goal vaccinating 90% girls against HPV, and this requires a robust understanding barriers uptake. Using household survey in three communities Malawi with parents/guardians aged 9-13 years, we collected analyzed data about intervention-amenable factors hypothesized be associated girls' HPV vaccination status. The 299 parent/guardian respondents provided information on 382...
We here evaluated the association between human papillomavirus (HPV) infection and vaginal infections, including bacterial vaginosis (BV), trichomonas vaginalis (TV), vulvovaginal candidiasis (VVC).A total of 4,449 women were enrolled in this study given gynecological examinations. HPV genotyping viral load determination performed using a real-time PCR. Vaginal infections diagnosed wet mounts secretions, gram-stained secretion smears, chemical enzyme kits.In study, overall HPV-positive rate...
Cervical cancer has caused numerous deaths in women worldwide over the past few decades. It is a serious clinical problem that needs to be solved, though its morbidity and mortality have declined recent years. The current treatments against cervical are hysterectomy, radiotherapy, chemotherapy, with certain limitations. Meanwhile, progress been made screening prevention of cancer, focusing on human papillomavirus (HPV) infection, which considered necessary but insufficient cause. This review...
Severe hand, foot, and mouth disease (HFMD) is sometimes associated with critical complications that can cause substantial child mortality. Activity of the vitamin D receptor (VDR) may influence outcomes enterovirus 71 (EV71) infection. This case‐control study aimed to assess association single‐nucleotide polymorphisms (SNPs) in gene encoding VDR severity EV71‐associated HFMD. We selected four SNPs based on linkage disequilibrium functional prediction, we tested them using SNPscan multiple...
Human papillomavirus (HPV) E6/E7 mRNA in situ hybridization (HPV RNAscope) appears to be a sensitive and specific technique detecting transcriptionally active HPV. We aimed examine the diagnostic utility of this endocervical adenocarcinoma (ECA), explore prognostic factors for ECA patients develop clinically useful nomogram based on clinicopathological parameters predict it.We retrospectively analyzed 200 with who had undergone surgery at Sun Yat-sen University Cancer Center from 2010 2014....
To understand the distributions of DNA and neutralizing antibodies human papillomavirus (HPV)16, 18 in 18-45 year-old women.Totally, 1494 women were enrolled through multistage random sampling Funing, Jiangsu province. Cervical exfoliated cells collected from them for HPV testing, serum samples taken detection HPV16, by using pseudovirion-based neutralization assay(PBNA).Among women, 28(1.9%) 188(12.6%) positive antibody HPV16 respectively, 15(1.0%) 60(4.0%) HPV18, respectively. There no...
Abstract Coxsackievirus A16 (CA16) remains the most common causative agent of hand, foot, and mouth disease (HFMD), is related to high incidence critical complications. Vitamin D receptor (VDR) activity might affect outcome CA16 infection. Our case‐control research aims evaluate relationship between VDR polymorphisms in gene encoding susceptibility severity HFMD due CA16. Three single‐nucleotide (SNPs) were selected according functional prediction linkage disequilibrium, examined utilizing...
AIM: To explore the relationship between food intolerance and diarrhea-dominant irritable bowel syndrome (dIBS). METHODS: In 68 patients with Rome II dIBS, we semi-quantitatively measured specific IgG antibody to 14 allergens in serum, then eliminated corresponding food. After 8 weeks, observed changes symptom frequency disease severity index. RESULTS: Compared normal control group, 48 dIBS appeared positive at least one allergen, a rate of 70.6%, difference was significant (P 2 allergens....
<div>AbstractPurpose:<p>Adults with T-cell lymphoblastic lymphoma (T-LBL) generally benefit from treatment acute leukemia (ALL)-like regimens, but approximately 40% will relapse after such treatment. We evaluated the value of CpG methylation in predicting for adults T-LBL treated ALL-like regimens.</p>Experimental Design:<p>A total 549 27 medical centers were included analysis. Using Illumina Methylation 850K Beadchip, 44 relapse-related CpGs identified 49 samples by...
Background: 25% ischemic strokes are wake-up or unwitnessed daytime and were excluded from thrombolysis due to the unclear-onset time. Whether is effective for these patients based on neuroimaging still unclear. We performed first meta-analysis evaluate effect of with stroke unknown onset.