A5028960820- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Fungal Biology and Applications
- Phytochemical compounds biological activities
- Sesquiterpenes and Asteraceae Studies
- Plant biochemistry and biosynthesis
- Microbial Natural Products and Biosynthesis
- Plant Molecular Biology Research
- Plant Gene Expression Analysis
- Plant Toxicity and Pharmacological Properties
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Bioactive Compounds
- Plant Pathogens and Fungal Diseases
- Polysaccharides and Plant Cell Walls
- Wood and Agarwood Research
- Marine Sponges and Natural Products
- Microbial Metabolism and Applications
- Insect Pest Control Strategies
- Chemical synthesis and alkaloids
- Plant-Microbe Interactions and Immunity
- Plant tissue culture and regeneration
- Plant Parasitism and Resistance
- Allelopathy and phytotoxic interactions
- Biological Activity of Diterpenoids and Biflavonoids
- Medicinal plant effects and applications
State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2017-2023
South China Agricultural University
2016-2023
Xiangya Hospital Central South University
2022-2023
Central South University
2022-2023
South China Botanical Garden
2010-2019
Chinese Academy of Sciences
2002-2017
Beijing Botanical Garden
2010-2017
Senju Pharmaceutical (United States)
2011
University of Chinese Academy of Sciences
2011
Guigang City People's Hospital
2010
Disease resistance of plants involves two distinct forms chemical communication with the pathogen: recognition and defense. Both are essential components a highly complex, multifaceted defense response, which begins non-self through perception pathogen-derived signal molecules results in production, inter alia, antibiotically active compounds (phytoalexins) cell wall-reinforcing material around infection site. To elucidate molecular details genomic basis underlying chains events, we used...
A novel quinic acid derivative, 5-O-trans-o-coumaroylquinic methyl ester (1), together with three known ones, chlorogenic (2), macranthoin F (3) and G (4), were isolated from the aerial parts of invasive plant Ageratina adenophora (Spreng.). The structure new compound 1 was elucidated on basis extensive spectroscopic analysis, including 1D- 2D-NMR techniques. Compounds 2–4 A. for first time. All compounds showed in vitro antibacterial activity toward five assayed bacterial strains,...
Dendrobium officinale is a precious traditional Chinese medicinal plant because of its abundant polysaccharides found in stems. We determined the composition water-soluble and starch content D. The extracted polysaccharide was as high 35% (w/w). Analysis monosaccharides showed that were dominated by mannose, to lesser extent glucose, small amount galactose, molar ratio 223:48:1. Although also found, less than 10%. This result indicated major stems non-starch polysaccharides, which might be...
Abstract Members of the MYB superfamily act as regulators in a wide range biological processes plants. Despite this, from Orchidaceae has not been identified, and genes related to bioactive water-soluble polysaccharide (WSP) biosynthesis are relatively unknown. In this study, we identified 159 165 two orchids, Phalaenopsis equestris Dendrobium officinale , respectively. The proteins were classified into four classes both orchids: MYB-related (MYBR), R2R3-MYB, 3R-MYB atypical proteins. MYBR...
Two new 30-noroleanane triterpenes, 2α,3β,20α-trihydroxy-30-norolean-12-en-28-oic acid (1), 2α,3β-dihydroxy-23-oxo-30-norolean-12,20(29)-dien-28-oic (2), were isolated from the pericarps of Akebia trifoliata, together with four known ones, 3β-akebonoic (3), 2α,3β-dihydroxy-30-noroleana-12,20(29)-dien-28-oic (4), 3α-akebonoic (5) and quinatic (6). Their structures established on basis detailed spectroscopic analysis, they all A. trifoliata for first time. Compounds 3−6 showed in vitro...
GDP-mannose pyrophosphorylase (GMP) catalyzed the formation of GDP-mannose, which serves as a donor for biosynthesis mannose-containing polysaccharides. In this study, three GMP genes from Dendrobium officinale (i.e., DoGMPs) were cloned and analyzed. The putative 1000 bp upstream regulatory region these DoGMPs was isolated cis-elements identified, indicates their possible role in responses to abiotic stresses. DoGMP1 protein shown be localized cytoplasm. To further study function gene,...
A phytochemical study on the aerial parts of
A bioassay-directed phytochemical study was conducted to investigate potential allelochemicals in the roots of invasive plant Ageratina adenophora. Eleven phenolic compounds, including seven new ones, 7-hydroxy-8,9-dehydrothymol 9-O-trans-ferulate (1), 7-hydroxythymol (2), 7,8-dihydroxythymol (3), 9-O-cis-ferulate (4), methyl (7R)-3-deoxy-4,5-epoxy-d-manno-2-octulosonate 8-O-trans-p-coumarate (5), 8-O-cis-p-coumarate (6), and 3-(2-hydroxyphenyl)propyl malonate (7), were isolated from a...
Abstract The WRKY family, one of the largest families transcription factors, plays important roles in regulation various biological processes, including growth, development and stress responses plants. In present study, 63 DoWRKY genes were identified from Dendrobium officinale genome. These classified into groups I, II, III a non-group, each with 14, 28, 10 11 members, respectively. ABA-responsive, sulfur-responsive low temperature-responsive elements 1-k upstream regulatory region genes....
The striking rise of methicillin-resistant Staphylococcus aureus (MRSA) infections has become a serious threat to public health worldwide. In an effort search for new anti-MRSA agents from natural products, bioassay-guided phytochemical study was conducted on the semi-mangrove plant Myoporum bontioides A. Gray, which led isolation two sesquiterpene alkaloids (1 and 2) six known furanosesquiterpenes (3⁻8). Their structures were elucidated basis extensive analysis their 1D, 2D NMR mass...
A bioassay-directed phytochemical study was carried out to investigate potential allelochemicals of the invasive plant Merremia umbellata subsp. orientalis (Hall. f.). Eight phenolic compounds, including a salicylic acid (SA)-derived new natural product, SA 2-O-β-D-(3',6'-dicaffeoyl)-glucopyranoside (1), and seven known ones 2-8 were isolated identified from two bioactive sub-fractions acetone extract this plant. The structure compound 1 established by spectral chemical methods. allelopathic...
Two new phytoecdysteroids, (25S)-20,22-O-(R-ethylidene)inokosterone and 20,22-O-(R-3-methoxycarbonyl)propylidene-20-hydroxyecdysone, together with six known phytoecdysteroids 3-8 were isolated from the roots of Achyranthes bidentata Blume. The structures established on basis spectroscopic studies chemical evidences. absolute configuration at C-25 in structure compound 3 was determined by means.
Ten pentacyclic triterpenoids including a new multiflorane triterpene acid, 2α,3β,23-trihydroxymultiflor-7-en-28-oic acid (<bold>1</bold>), and lupane monoglucoside named akebiaoside C (<bold>2</bold>), were obtained from the leaves of<italic>Akebia trifoliata</italic>.
Two new thymol derivatives, 7,9-diisobutyryloxy-8-ethoxythymol (1) and 7-acetoxy-8-methoxy-9-isobutyryloxythymol (2), were isolated from fresh roots of Ageratina adenophora, together with four known compounds, 7,9-di-isobutyryloxy-8-methoxythymol (3), 9-oxoageraphorone (4), (-)-isochaminic acid (5) (1α,6α)-10-hydroxycar-3-ene-2-one (6). Their structures established on the basis detailed spectroscopic analysis, they all A. adenophora for first time. All compounds tested their in vitro...
A novel sesquiterpene alcohol, named frabenol (1), was isolated from liquid cultures of Fimetariella rabenhorstii A20, an endophytic fungus the agarwood-forming plant Aquilaria sinensis (Lour.) Gilg. The structure new compound elucidated on basis spectroscopic methods. finding a sesquiterpenoid in F. A20 implied that fungi agarwood-producing plants could also contribute to generation fragrant chemicals during agarwood formation processes.
Abstract A new sesquiterpene, eremophil‐9‐ene‐11,12,13‐triol ( 1 ), a oxazole, 4‐(2‐hydroxyethyl)‐5‐methyloxazole 2 and the two known lactones, 5′‐hydroxyalternariol 3 ) alternariol 4 were isolated from extract of Phomopsis sp. A240, an endophytic fungus bark Taxus chinensis var. mairei. The structures compounds determined by analyses their spectroscopic data, as well comparison with literature reports. evaluated for cytotoxic antioxidant activities.