A5026679677- Neurological disorders and treatments
- Obsessive-Compulsive Spectrum Disorders
- Transcranial Magnetic Stimulation Studies
- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Functional Brain Connectivity Studies
- Epilepsy research and treatment
- Parkinson's Disease Mechanisms and Treatments
- EEG and Brain-Computer Interfaces
- Circadian rhythm and melatonin
- Neuroinflammation and Neurodegeneration Mechanisms
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Genetic and Kidney Cyst Diseases
- Neurofibromatosis and Schwannoma Cases
- Acute Ischemic Stroke Management
- Pharmacological Effects and Toxicity Studies
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Fetal and Pediatric Neurological Disorders
- Neuroblastoma Research and Treatments
- Bone Tumor Diagnosis and Treatments
- Genetic Neurodegenerative Diseases
- Sarcoma Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
Baylor College of Medicine
2022-2025
Dartmouth College
2024
The University of Texas at Austin
2023
Abstract The default mode network (DMN) is a widely distributed, intrinsic brain thought to play crucial role in internally directed cognition. present study employs stereo-EEG 13 human patients, obtaining high resolution neural recordings across multiple canonical DMN regions during two processes that have been associated with creative thinking: spontaneous and divergent thought. We probe these DMN-associated higher cognitive functions through mind wandering alternate uses tasks,...
Recent advances in surgical neuromodulation have enabled chronic and continuous intracranial monitoring during everyday life. We used this opportunity to identify neural predictors of clinical state 12 individuals with treatment-resistant obsessive-compulsive disorder (OCD) receiving deep brain stimulation (DBS) therapy ( NCT05915741 ). developed our neurobehavioral models based on recordings the region ventral striatum an initial cohort five patients tested validated them a held-out seven...
Enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles (cerebral ventriculomegaly), cardinal feature congenital hydrocephalus (CH), is increasingly recognized among patients with autism spectrum disorders (ASD).
Deep brain stimulation (DBS) for Parkinson disease (PD) is traditionally performed with awake intraoperative testing and/or microelectrode recording. Recently, however, the procedure has been increasingly under general anesthesia image-based verification. The authors sought to compare structural and functional networks engaged by asleep PD-DBS of subthalamic nucleus (STN) correlate them clinical outcomes.Levodopa equivalent daily dose (LEDD), pre- postoperative motor scores on Movement...
Gangliogliomas (GGs) are rare tumors of the central nervous system composed neoplastic neural and glial cells typically low-grade. Intramedullary spinal anaplastic GGs (AGG) rare, poorly understood, often aggressive that can result in widespread progression along craniospinal axis. Due to rarity these tumors, data lacking guide clinical pathologic diagnosis standard care treatment. Here, we present a case pediatric AGG provide information on our institutional approach work-up highlight...
Osteomas are benign bony lesions that can occur throughout the craniofacial skeleton. Surgical excision be an effective treatment, as recurrence is relatively uncommon. Outside of incomplete resection, causes poorly documented, especially in pediatric population. Exchange cranioplasty autologous reconstructive surgical option for patients all ages, and it treatment large calvarial osteomas. Recurrent site have not been well described literature, with only 3 documented reports. In this study,...
BACKGROUND AND OBJECTIVES: Directional deep brain stimulation (DBS) enables treatment optimization by current steering using segmented leads. Identification of the lead's rotational orientation is critical to guide programming decisions. Orientation often assessed during or immediately after implant, but degree lead rotation in following weeks not well appreciated. Our objective was measure DBS changes within first few surgery. METHODS: We retrospectively reviewed clinical records patients...
The optimal approach to the management of intracranial atherosclerotic disease (ICAD) at time mechanical thrombectomy (MT) for large vessel occlusion (LVO) remains controversial. goal this study is characterize current practices concerning challenging clinical situation in a survey practicing neurointerventionalists.An electronic questionnaire was sent cross-section North American academic neurointerventionalists using publicly available contact information and departmental websites. Prior...
Resection of brain lesions associated with refractory epilepsy to achieve seizure control is well accepted. However, concurrent behavioral effects these such as changes in mood, personality, and cognition the surgery on behavior have not been characterized. We describe 5 children epileptogenic significant abnormalities which improved after surgery.Five (ages 3-14 years) major lesional were identified treated at our center. Behavioral problems included academic impairment, impulsivity,...
INTRODUCTION: Deep brain stimulation (DBS) of the ventral capsule/ventral striatum (VC/VS) improves symptoms in ∼66% patients with treatment-resistant obsessive-compulsive disorder (OCD). However, a common adverse effect VC/VS DBS is hypomania, marked by decreased need for sleep and increased risk-taking behaviors. Modern devices have enabled 24-hour collection neural data, allowing tracking circadian rhythms reflected local field potentials (LFPs). METHODS: We implanted six OCD device...
PulseRider is an endovascular device that can be a useful adjunctive for wide-necked bifurcation aneurysms. However, its use in distal vessels such as the anterior cerebral artery (ACA) has not been widely reported.The authors reported case of 75-year-old woman who underwent coiling 6.9-mm ACA aneurysm with assistance. Using partially intraaneurysmal deployment technique, was successfully embolized, resulting Raymond-Roy class II occlusion without intra- or periprocedural complications.This...