- Eating Disorders and Behaviors
- Psychosomatic Disorders and Their Treatments
- Parkinson's Disease Mechanisms and Treatments
- Mindfulness and Compassion Interventions
- Fibromyalgia and Chronic Fatigue Syndrome Research
- COVID-19 and Mental Health
- Attention Deficit Hyperactivity Disorder
- Healthcare professionals’ stress and burnout
- Patient Satisfaction in Healthcare
- Neurological disorders and treatments
- Psychological Well-being and Life Satisfaction
- Physical Activity and Health
- Patient-Provider Communication in Healthcare
- Botulinum Toxin and Related Neurological Disorders
- Musculoskeletal Disorders and Rehabilitation
- Obesity, Physical Activity, Diet
- Cancer, Hypoxia, and Metabolism
- Electrolyte and hormonal disorders
- Genetic Neurodegenerative Diseases
- Behavioral Health and Interventions
- Osteoarthritis Treatment and Mechanisms
- Health and Lifestyle Studies
- Pregnancy and Medication Impact
- Posttraumatic Stress Disorder Research
- Cancer-related Molecular Pathways
Peking Union Medical College Hospital
2021-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2024
Yale University
2021-2023
University of Bologna
2020-2022
Baylor College of Medicine
2017
Demoralization is quite prevalent in patients with Parkinson disease (PD). Unrecognized or untreated, demoralization may progress, at times, to demands for euthanasia and the desire suicide. Typically, PD do not complain of being "demoralized"; rather, they report disruptions quality their lives. Hence, early identification health-related life (HRQoL) specifically associated prompt earlier recognition treatment. Published data on such associations, however, could be found. Alleviation likely...
This pilot randomized controlled trial evaluates the preliminary efficacy of a 4-month well-being therapy (WBT) and lifestyle intervention among adults with type 2 diabetes overweight/obesity.Fifty-eight patients were recruited from two outpatient clinics to receive WBT-lifestyle or alone. Data collected at baseline (T0), immediate postintervention (T1), 6-month follow-up (T2), 12-month (T3). Primary outcomes included changes in weight, psychological distress, well-being, whereas secondary...
Although the literature suggested that impaired psychological well-being (PWB) is associated with obesity, evidence on role of PWB in weight outcomes limited and inconclusive. This research aimed to investigate joint achieving clinically significant loss (CWL; 5% initial weight) through a comprehensive lifestyle intervention for obesity using broad-based evaluation.This study prospective cohort 96 patients attending loss. Data weight, lifestyle, PWB, distress, were collected before after...
The objective of this study was to determine whether depression and anxiety are mediators between perceived stress demoralization via a loss the cognitive map get out predicament manifesting as subjective incompetence. Ninety-five consecutive outpatients with Parkinson's disease were evaluated for stress, depression, anxiety, incompetence, using reliable valid scales. Inclusion criteria ages 40-90, intact cognition, no current history substance use. setting Movement Disorders Clinic at...
Introduction: Stress may lead to allostatic overload. Well-being therapy (WBT) might mitigate it by enhancing psychological well-being and protecting from symptoms. Since no reports are available on the use of WBT in overload, we evaluated online effects reducing overload medical workers during coronavirus pandemic. Methods: Sixty-six participants with were enrolled randomly assigned eight sessions (n = 32) or an psychoeducation program healthy lifestyle (CON) 34). The primary outcome was...
Objectives The objective of this study was to the interrelations demoralization, depression, and resilience in patients with Parkinson disease, and, more specifically, determine if higher disease is associated lower or both. Methods Outpatients ( N = 95) were assessed for resilience, as well sociodemographic, clinical, treatment-related variables. Bivariable associations, standard regressions, linear regression copula correction, correspondence analysis used analyze data. Results Although...
Abstract Background Although patient-centred medical services are widely recognized and accepted, how to define evaluate them remains a controversial topic. Objectives This study attempts the underlying structure of Patient-Practitioner Orientation Scale (PPOS) with homogenous population clarify connotation patient-centredness. Methods In this cross-sectional study, 279 7th year Chinese students in were selected examine internal PPOS by means consistency, exploratory, confirmatory factor...
Abstract Behavioural lifestyle interventions focused on diet and physical activity are a cornerstone for the treatment of obesity. However, their effects vary substantially across individuals in terms magnitude durability. Personalized approaches that target psychological well‐being may be promising to facilitate healthy behaviours sustained weight loss. This preliminary study aimed explore whether sequential combination behavioural intervention (BLI) therapy (WBT) result more favourable...
Abstract Background No studies have reported on how to relieve distress or relax in medical health workers while wearing protective equipment coronavirus disease 2019 (COVID-19) pandemic. The study aimed establish which relaxation technique, among six, is the most feasible first-line equipment. Methods This was a two-step collecting data with online surveys. Step 1: 15 were trained use six different techniques and two 2: revealed by step 1 quantitatively tested sample of 65 terms efficacy,...
Introduction Hyperemesis gravidarum (HG) is a condition characterised by dehydration, electrolyte imbalance, lack of nutrition and at least 5% loss in body weight, occurring the first half pregnancy. The aim this trial to examine efficacy group biofeedback treatment on patients with HG psychosomatic symptoms, which will be evaluated through revised version Diagnostic Criteria for Psychosomatic Research (DCPR-R). Methods analysis In single-blinded randomised controlled clinical trial, 68...
Abstract Reprogramming of metabolic pathways is one the central hallmarks cancer cell growth and survival to support anabolic energetic demands. Rapidly proliferating tumor cells utilize increased amounts glucose for energy generation macromolecule biosynthesis, yet it still poorly understood how glucose-flux accentuates aggressive metastatic tumor. Understanding molecular genetic regulators these metabolic-programs critical discover new drug targets therapy. Here, we report that oncogenic...
Abstract Background: Although patient-centered medical services are widely recognized and accepted, how to define evaluate them remains controversial. Objectives: This study attempts the underlying structure of PPOS with a homogenous population clarify connotation patient-centeredness. Methods: In this cross-sectional study, 279 Chinese students in grade 7 were selected examine internal by means consistency, exploratory factor, confirmatory factor analyses. Results: Both two-factor model...