A5067293999- Hematopoietic Stem Cell Transplantation
- Immunotherapy and Immune Responses
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Nanoplatforms for cancer theranostics
- Advanced Photocatalysis Techniques
- Luminescence and Fluorescent Materials
- Mesenchymal stem cell research
- Advanced Nanomaterials in Catalysis
- 3D Printing in Biomedical Research
- Click Chemistry and Applications
- Immune Response and Inflammation
- Advanced biosensing and bioanalysis techniques
- Electrocatalysts for Energy Conversion
- Nanomaterials for catalytic reactions
- Microbial Fuel Cells and Bioremediation
- Xenotransplantation and immune response
- Catalytic Processes in Materials Science
- Gold and Silver Nanoparticles Synthesis and Applications
- Workplace Violence and Bullying
- Additive Manufacturing and 3D Printing Technologies
- Copper-based nanomaterials and applications
- Nanocluster Synthesis and Applications
- Photoreceptor and optogenetics research
- Catalysis and Oxidation Reactions
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2025
Chinese Academy of Sciences
2019-2025
Institute of Chemistry
2019-2025
Beijing National Laboratory for Molecular Sciences
2019-2025
Shanghai Tenth People's Hospital
2023-2025
Tongji University
2023-2025
Capital Medical University
2025
Jiangxi University of Traditional Chinese Medicine
2025
Beijing Forestry University
2024
Sun Yat-sen University
2024
Supported nanoparticles (NPs) of nonplasmonic transition metals (Pd, Pt, Rh, and Ir) are widely used as thermally activated catalysts for the synthesis important organic compounds, but little is known about their photocatalytic capabilities. We discovered that irradiation with light can significantly enhance intrinsic catalytic performance these metal NPs at ambient temperatures several types reactions. These strongly absorb mainly through interband electronic transitions. The excited...
Palladium (Pd)-catalyzed cross-coupling reactions are among the most important methods in organic synthesis. We report discovery of highly efficient and green photocatalytic processes by which reactions, including Sonogashira, Stille, Hiyama, Ullmann, Buchwald–Hartwig can be driven with visible light at temperatures slightly above room temperature using alloy nanoparticles gold Pd on zirconium oxide, thus achieving high yields. The absorb light, their conduction electrons gain energy, is...
Pickering emulsions represent an important class of functional materials with potential applications in sustainability and healthcare. Currently, the synthesis relies heavily on use strongly adsorbing molecular modifiers to tune surface chemistry nanoparticle constituents. This approach is inconvenient potentially a dead-end for many since adsorbed prevent interactions between nanosurface its surroundings. Here, we demonstrate general modifier-free construct by using combination stabilizer...
Abstract Conjugated polymers (CPs) have promising applications in biomedical fields, such as disease monitoring, real‐time imaging diagnosis, and treatment. As a luminescent material with tunable emission, high brightness excellent stability, CPs are widely used fluorescent probes biological detection imaging. Rational molecular design structural optimization broadened absorption/emission range of CPs, which more conductive for diagnosis precision therapy. This review provides comprehensive...
Bone marrow transplantation offers great promise for treating a number of disease states. However, the widespread application this approach is dependent upon development less toxic methods to establish chimerism and avoid graft-versus-host (GVHD). CD8+/TCR− facilitating cells (FCs) have been shown enhance engraftment hematopoietic stem (HSCs) in allogeneic recipients without causing GVHD. In present studies, we identified main subpopulation FCs as plasmacytoid precursor dendritic (p-preDCs)....
Selective epoxidation of various alkenes with molecular oxygen (O2) under mild conditions is a longstanding challenge in achieving syntheses epoxides. Cu-based catalysts have been found to be catalytically active for selective epoxidations. However, the application copper nanoparticles (CuNPs) photocatalyzed epoxidations encumbered by instability CuNPs air. Herein we report that supported on titanium nitride (TiN) without additional stabilizers not only are stable air but also can catalyze...
The photocatalytic reduction of nitroaromatics on Ag–Cu alloy NPs can maintain the selectivity to azoxy compounds, whereas Ag mainly obtain azo compounds.
Here we report a class of photocatalysts: mixed-valence vanadium oxide particles grafted onto variety supports. In these catalysts V6O13 species with mixed oxidation states (V4+ or V5+) are believed to be catalytically active sites. These successfully enable alcohol selectively produce aldehydes and ketones using O2 as the oxidant. The catalytic process is driven by visible light irradiation at room temperature and, most importantly, progresses negligible overoxidation. can even oxidize...
A light-harvesting polymer is used to augment photosynthesis through regulating state transition of photosystems I and II.
Remote control of the therapeutic process is an ideal strategy for maximizing efficacy and avoiding side effects, especially cancer immunotherapy. Herein, a conjugated polymer nanoparticles (CPNs)-mediated optogenetic system in situ activation immunotherapy under near-infrared laser irradiation reported. This composed photothermal CPNs interferon-gamma (IFN-γ) plasmid driven by heat shock promoter HSP70. The photothermally responsive serve as photo-heat nanotransducer to trigger gene...
Abstract Complicated vessels pervade almost all body tissues and influence the pathophysiology of human significantly. However, current fabrication strategies have limited success at multiscale vascular biofabrication. This study reports a methodology to fabricate soft vascularized tissue centimeter scale using multimaterial bioprinting by customized multistage‐temperature‐control printer. The printed constructs can be perfused via branched endothelialized vasculatures support well‐formed 3D...
Abstract Shape‐morphing actuators, which can breathe with the accompany of morphology changes to mimic botanical events, are challenging fabricate soft hydrogel materials. Herein, 4D printed‐smart actuators reported that not only dynamically deform but also generate oxygen (O 2 ) upon external stimulations. The printed breathing featured spinach leaf‐derived thylakoid membrane (nanothylakoid) for photothermal conversion and catalytical O evolution, a poly( N ‐isopropylacrylamide) (PNIPA)...
Abstract Cell surface engineering with functional polymers is an effective strategy to modulate cell activity. Here, a bio‐palladium catalyzed polymerization was developed for in situ synthesis of conjugated on living surfaces. Through Sonagashira polymerization, photoactive polyphenyleneethynylene (PPE) synthesized the via cell‐generated bio‐Pd catalyst. The formed PPE identified by excellent light‐harvest capacity and blue fluorescence surfaces E. coli C. pyrenoidosa . Besides imaging...
A printable ink composed of a photoactive cationic conjugated polymer (PPV) and gelatin/alginate/hyaluronic acid was developed for 3D printing artificial skin patches with the biofunctions anti-infection augmenting wound repair.
Living materials are worked as an inside collaborative system that could naturally respond to changing environmental conditions. The regulation of bioelectronic processes in living be effective for collecting biological signals and detecting biomarkers. Here, we constructed a material with conjugated polymers poly[3-(3'-N,N,N-triethylamino-1'-propyloxy)-4-methyl-2,5-thiophene chloride] (PMNT) Shewanella oneidensis MR-1 biofilm. In addition, the was integrated flexible device lactate...
Abstract A conductive polymer‐based photosynthetic biohybrid is constructed to enhance biological nitrogen fixation by increasing nitrogenase activity in the non‐photosynthetic bacterium Azotobacter Chroococcum ( A. ). The light‐harvesting cationic poly(fluorene‐alt‐phenylene) (PFP) electrostatically binds surface of bacteria and possesses satisfactory conductivity facilitate electron transfer bacterium, promoting pathway through redox proteins on when under illumination. Therefore,...
Developing artificial symbionts beyond natural synthesis limitations would bring revolutionary contributions to agriculture, medicine, environment, etc. Here, we initiated a solar-driven multi-organism symbiont, which was assembled by the CO 2 fixation module of Synechocystis sp., N Rhodopseudomonas palustris , biofunctional polypeptides Bacillus licheniformis and electron transfer conductive cationic poly(fluorene- co -phenylene) derivative. The modular design broke pathway synthesize...
The regulation of oxidative stress in living cells is essential for maintaining cellular processes and signal transduction. However, developing straightforward strategies to activate stress-sensitive membrane channels situ poses significant challenges. In this study, we present a chemiluminescence resonance energy transfer (CRET) system based on conjugated oligomer, oligo(p-phenylenevinylene)-imidazolium (OPV-Im), designed the activation transient receptor potential melastatin 2 (TRPM2)...
The Copenhagen Psychosocial Questionnaire (COPSOQ) is an international instrument designed for the assessment and improvement of psychosocial conditions in workplaces research purposes. After International COPSOQ Network took over responsibility development COPSOQ, a new version was published 2019 (COPSOQ III). However, there no widely recognized measuring work factors, insufficient exists regarding use III within Chinese setting. This study seeks to conduct preliminary validation long III....