A5030108744- Hip and Femur Fractures
- Gynecological conditions and treatments
- Bone fractures and treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Pelvic and Acetabular Injuries
- Bone and Joint Diseases
- MicroRNA in disease regulation
- Intestinal and Peritoneal Adhesions
- Endometrial and Cervical Cancer Treatments
- Cancer-related molecular mechanisms research
- Bone health and osteoporosis research
- Venous Thromboembolism Diagnosis and Management
- Hip disorders and treatments
- Maternal and Perinatal Health Interventions
- Cancer-related gene regulation
- Apelin-related biomedical research
- Signaling Pathways in Disease
- Healthcare and Venom Research
- Intraocular Surgery and Lenses
- Traditional Chinese Medicine Analysis
- Ophthalmology and Visual Impairment Studies
- Nuclear Receptors and Signaling
- Surgical Sutures and Adhesives
Sun Yat-sen University
2016-2025
China-Japan Friendship Hospital
2015-2025
The Seventh Affiliated Hospital of Sun Yat-sen University
2020-2025
Shenzhen Second People's Hospital
2020-2021
Shenzhen University Health Science Center
2020-2021
Eighth Affiliated Hospital of Sun Yat-sen University
2020
The First Affiliated Hospital, Sun Yat-sen University
2016-2019
Nantong University
2019
Huashan Hospital
2015
Fudan University
2015
Intrauterine adhesion (IUA) is a common uterine cavity disease which can be caused by mechanical damage that may eventually lead to infertility and pregnancy abnormalities. Since the effect of therapeutic drugs appears disappointing, cell therapy has emerged as an alternative choice for endometrium regeneration. The aim this study investigate whether combination hydrogel Pluronic F-127 (PF-127), Vitamin C (Vc), bone marrow stromal (BMSC) mixture could feasible strategy improve endometrial...
This study aimed to investigate the effects of estrogen in combination with aspirin and intrauterine balloon on uterine endometrial repair reproductive prognosis patients after surgery for severe adhesion (sIUA). We prospectively recruited 114 sIUA. Intrauterine device (IUD) was placed oral administered surgery. Patients were divided into control group group. In addition, subdivided nonballoon Results showed that, therapy, increase thickness groups superior (<mml:math...
Abstract Background Mesenchymal stem cells (MSCs) have exerted their brilliant potential to promote heart repair following myocardial infarction. However, low survival rate of MSCs after transplantation due harsh conditions with hypoxic and ischemic stress limits therapeutic efficiency in treating cardiac dysfunction. ELABELA (ELA) serves as a peptide hormone which has been proved facilitate cell growth, survival, pluripotency human embryonic cells. Although ELA works an endogenous ligand G...
<title>Abstract</title> Background: Hip fractures are common in elderly patients, with some experiencing contralateral fractures. Even so, information on predictors of hip adults is lacking. In this study, we investigated risk factors for after surgical treatment primary Methods: This was a prospective cohort study 115 patients aged ≥65 years low-energy The clinical parameters evaluated included age, sex, bone mineral density (BMD), T score, and flexor strength deficit. Patients were...
Abstract In males, 95% of testosterone is synthesized by Leydig cells, and a deficiency in this synthesis will cause metabolic disorders multiple organ dysfunction. Testosterone not only affected aged or diseased which have been studied extensively, but also closely related to the development testis. At present, focus on mechanism testis includes epigenetic hormone regulation. However, testicular constrained external tough tunica albuginea, suggesting that mechanical signals may play an...
To evaluate the outcome and efficacy of LISS (Less Invasive Stabilization System; Synthes USA, Paoli, PA) for treatment proximal femoral fractures to find another appropriate minimally invasive surgery these in which intramedullary nailing may be difficult.A consecutive prospective randomized clinical study.University teaching hospital.Between May 2006 March 2008, 64 patients who had a fracture were treated with fixation either or PFNA (Proximal Femoral Nail Anti-rotation; USA).LISS...
Objective: To investigate the frequency of deep vein thrombosis (DVT) in patients aged over 80 years on admission after intertrochanteric femur fracture and to explore risk factors DVT.
This study aimed to develop and evaluate a sustained drug delivery system for the treatment of osteoarticular tuberculosis (TB) address issues surrounding low concentration in lesions bone defects or nonunion after debridement. The effects rifapentine on proliferation cell cycle marrow mesenchymal stem cells (BMSCs) were evaluated by Cell Counting Kit-8 (CCK-8) flow cytometry. Rifapentine polylactic acid (PLA) sustained-release microspheres (RPSMs) prepared through double emulsion solvent...
To investigate the characteristics of deep infiltrating endometriosis (DIE) lesion distribution when associated with ovarian endometrioma (OEM).The present study analyzed retrospective data obtained by First Affiliated Hospital Sun Yat-sen University, between June 2008 to 2016. A total 304 patients underwent laparoscopic surgery for complete removal one experienced surgeon, and histological confirmation OEM DIE was conducted each patient. Clinical were recorded patient from medical,...
Background Formononetin, which is used as neuroprotective medicine, was reported to have benefits for Alzheimer’s disease (AD). However, little known on how Formononetin exerts these beneficial effects. In this study, we investigated the molecular mechanisms through increased soluble-APPa (sAPPa) secretion and thus in human-APP Swedish mutation cell cultures (N2a-APP cell). Method results By using N2a-APP combined with hypoxia treatment, confirmed that chronic treatment could effects,...
Objective To investigate the effect of intraoperative dripping intravenous tranexamic acid (TXA) on perioperative blood loss in elderly patients undergoing hip arthroplasty for femoral neck fracture. Methods From January 2016 to August 2017, 118 with fracture were treated at Department Orthopaedics, China-Japan Friendship Hospital. They 45 males and 73 females, an average age 77.1 years. Of them, 60 (TXA group) subjected TXA over 10 minutes by 2 doses (15 mg/kg dissolved 100 mL...
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Amyloid-β (Aβ) peptide, which can invoke a cascade of inflammatory responses, is considered to play causal role in the development and progress Alzheimer’s disease (AD). Xylocoside G (XG) an active compound isolated from traditional Chinese medicinal plant, Itoa orientalis. We have previously reported that XG has neuroprotective effects, with mechanism yet unknown. In this study, we investigated possible mechanisms underlying neuroprotection against Aβ-induced toxicity SH-SY5Y cells primary...
Results In this study, we found that LPL-deficient mice exhibited increased latency to escape platform and mistake frequency. Decreased in the stepdown passive avoidance test was observed, consistent with impaired learning memory these mice. Transmission electron microscopy revealed a significant decrease number of pre-synaptic vesicles hippocampus The levels marker synaptophysin were also reduced while post-synaptic PSD-95 remained unchanged LPL deficiency frequency miniature excitatory...
Abstract Background: To investigate the characteristics of deep infiltrating endometriosis (DIE) lesion distribution when associated with ovarian endometrioma (OEM). Methods: The present study analyzed retrospective data obtained by First Affiliated Hospital Sun Yat-sen University, between June 2008 to 2016. A total 304 patients underwent laparoscopic surgery for complete removal one experienced surgeon, and histological confirmation OEM DIE was conducted each patient. Clinical were recorded...