A5100323447- Cholangiocarcinoma and Gallbladder Cancer Studies
- Bladder and Urothelial Cancer Treatments
- Knee injuries and reconstruction techniques
- Cholesterol and Lipid Metabolism
- Gallbladder and Bile Duct Disorders
- Total Knee Arthroplasty Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatic and Hepatic Oncology Research
- Surgical Simulation and Training
- Medical Research and Treatments
- Genomics, phytochemicals, and oxidative stress
- Coenzyme Q10 studies and effects
- Adhesion, Friction, and Surface Interactions
- Pancreatitis Pathology and Treatment
- Augmented Reality Applications
- Vascular Malformations and Hemangiomas
- Cancer Mechanisms and Therapy
- Anatomy and Medical Technology
- Genetic and Kidney Cyst Diseases
- Circular RNAs in diseases
- Autophagy in Disease and Therapy
- Mesenchymal stem cell research
- Head and Neck Anomalies
- Testicular diseases and treatments
- Nausea and vomiting management
Hebei Medical University
2023
Fourth Hospital of Hebei Medical University
2023
Beijing Jishuitan Hospital
2022
Peking University
2012-2022
Affiliated Hospital of Qingdao University
2022
Qingdao University
2022
Tianjin Nankai Hospital
2019
Xi’an Children’s Hospital
2017
First Hospital of Shanxi Medical University
2017
Shanxi Medical University
2017
Mesenchymal stem cells (MSCs) can be successfully induced to differentiate into insulin-producing （IPCs) by a variety of small molecules and cytokines in vitro. However, problems remain, such as low transdifferentiation efficiency poor maturity trans-differentiated cells. The damaged pancreatic secreted large amount soluble proteins, which were able promote pancreative islet regeneration MSCs differentiation. In this study, we utilized the rat injured tissue extract modulate bone...
/Objective: Biological factors such as platelet-rich plasma (PRP) combined with anterior cruciate ligament (ACL) primary repair technology are used to treat ACL injury. However, the protective mechanism of PRP for fibroblasts under hypoxia condition is still unknown. The aim this study was investigate effect on and illustrate regulating condition.The cells were divided into three groups: control group, group pretreatment group. Lethal dose (LD) 50 induction time maximum efficacy...
The Image-Guided Surgery Toolkit (IGSTK) is an open source C++ software library that provides the basic components needed to develop image-guided surgery applications. focus of toolkit on robustness using a state machine architecture. This paper presents overview project based recent book which can be downloaded from igstk.org. includes introduction projects, discussion our development process and best practices were developed, requirements. also architecture framework main components....
Virtual environments for training manipulative skills in laparoscopic surgery are now well established as research areas. Tissue dissection however has not yet been adequately addressed. We have developed a virtual module which the task is to dissect 3D tissue model using simulated L-hook. Three metrics designed assess performance. 1) Total deviation of actual cut path from drawn path. 2) contact time between instrument and tissue. 3) Contact discontinuity. The objective was design basic...
Analysis of the change cells in bile is an evolving research field biliary pathophysiology and has potential value diagnosis therapy. However, laboratory studies cell across world are scarce. Bile was collected from clinical patients with cholangiocarcinoma (CC). To optimize separation method CC, we studied factors that may affect vitality including dilution buffer, centrifugal force, time, store time temperature. Then these were modified performance evaluated by flow cytometry respect to...
Results In this study, we found that LPL-deficient mice exhibited increased latency to escape platform and mistake frequency. Decreased in the stepdown passive avoidance test was observed, consistent with impaired learning memory these mice. Transmission electron microscopy revealed a significant decrease number of pre-synaptic vesicles hippocampus The levels marker synaptophysin were also reduced while post-synaptic PSD-95 remained unchanged LPL deficiency frequency miniature excitatory...
The present study aimed to clarify the association between ezrin-radixin-moesin-binding phosphoprotein-50 (EBP50) expression level and tumor phenotype clinicopathological features of extrahepatic bile duct carcinoma. Tissue samples from patients with carcinoma (54 cases) normal epithelia gallbladder cholecystitis (20 were collected, immunohistochemical staining was used detect levels EBP50 in these tissues. In addition, small interfering (si)RNA-EBP50 knock down QBC939 human...
Abstract Objective : The aim of the present study was to investigate specific mechanism by which MSCs protect against SA-AKI. Methods Male C57BL/6 mice underwent cecal ligation and puncture operation induce sepsis then received either normal IgG or (1* 10 6 cells intravenously) plus Gal-9 soluble-Tim-3 3h after surgery. Results After operation, injection with had a higher survival rate than treatment group. Treatment decreased serum creatinine blood urea nitrogen levels improved recovery...
Fragestellung: Gegenuber dem Huft- und Kniegelenk hat die Endoprothetik des Radiokarpalgelenks bis heute keinen vergleichbaren Durchbruch erlangen konnen. Dieses liegt u.a. daran, dass praklinische Prufungen dieser Prothesen unter realitatsgetreuen Bedingungen nicht moglich[for full text, please go to the a.m. URL]
Little information is available regarding the therapeutic efficacy of immune checkpoint inhibitors and prediction DNA damage-repair (DDR) genes in mixed testicular germ-cell tumors (TGCTs). Here we report a pretreated patient with metastatic TGCT harboring variations three important DDR - BRCA2, MSH6 PMS2 identified by next-generation sequencing using plasma-based circulating tumor DNA. He obtained stable clinical benefit from PD-1 blockade. At latest follow-up, he had progression-free...
<p>Knockdown of circ0008399/WTAP/TNFAIP3 pathway decreases the chemosensitivity BC cells to CDDP.</p>
<p>Knockdown of circ0008399/WTAP/TNFAIP3 pathway decreases the chemosensitivity BC cells to CDDP.</p>
<p>Knockdown of circ0008399/WTAP/TNFAIP3 pathway inhibits the viability and anchorage-independent growth BC cells.</p>
<p>Knockdown of circ0008399/WTAP/TNFAIP3 pathway inhibits the viability and anchorage-independent growth BC cells.</p>
Objective To investigate the efficacy of endoscopy for treatment benign biliary stricture after surgery.Methods The clinical data 127 patients with surgery at First Hospital Lanzhou University from January 2007 to December 2011 were retrospectively analyzed.According Bismuth classification,there 60 type Ⅰ,35 Ⅱ,21 Ⅲ and 11 Ⅳ.The efficacies different subtypes analyzed.Results location severity confirmed by endoscopic retrograde cholangiopancreatography (ERCP) + cholangiography.Sixteen (...