A5059188997- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Inflammasome and immune disorders
- Ferroptosis and cancer prognosis
- interferon and immune responses
- Cardiovascular Disease and Adiposity
- Cancer, Lipids, and Metabolism
- Antiplatelet Therapy and Cardiovascular Diseases
- MicroRNA in disease regulation
- Cerebrovascular and Carotid Artery Diseases
- Heme Oxygenase-1 and Carbon Monoxide
- Cardiac Fibrosis and Remodeling
- Acute Ischemic Stroke Management
- Peripheral Artery Disease Management
- Neuropeptides and Animal Physiology
- Cardiac Valve Diseases and Treatments
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Anhui University of Traditional Chinese Medicine
2022-2025
Child Trends
2023
Handan College
2021-2022
Ferroptosis is a newly identified form of non-apoptotic programmed cell death, characterized by the iron-dependent accumulation lethal lipid reactive oxygen species (ROS) and peroxidation membrane polyunsaturated fatty acid phospholipids (PUFA-PLs). unique among other death modalities in many aspects. It initiated excessive oxidative damage due to iron overload compromised antioxidant defense systems, including system Xc-/ glutathione (GSH)/glutathione peroxidase 4 (GPX4) pathway...
Brain-derived neurotrophic factor (BDNF) exerts protective roles against dyslipidemia, atherosclerosis, and inflammation in cardiovascular diseases; meanwhile, it retards CD4+ T cell differentiation into helper (Th)1 Th17 cells. Hence, this study aimed to investigate the linkage of serum BDNF with Th1/Th2 ratio, Th17/regulatory (Treg) major adverse events (MACE) risk coronary heart disease (CHD) patients.This prospective detected 210 CHD patients, 50 controls (DCs), healthy (HCs) using an...
Background/Objectives: Studies have shown that Atractylenolide I (AT-I) can exert anti-inflammatory and anti-oxidative effects, protecting against the development of various kinds cardiovascular diseases. However, whether AT-I prevents nicotine-induced atherogenesis is unknown. This study was designed to explore effects on macrophage pyroptosis progression atherosclerosis. Methods: RT-qPCR Western blot were used detect mRNA protein levels TXNIP pyroptosis-related factors in THP-1-derived...
MicroRNA-34a (miR-34a) plays an essential role in regulating blood lipid, inflammation, cell adhesion molecules, and atherosclerosis, the latter factors are closely involved etiology of coronary heart disease (CHD). However, clinical value miR-34a CHD patients' management is rarely reported. Hence, this study aimed to assess correlation with risk, artery stenosis, inflammatory cytokines, molecules CHD.A total 203 patients 100 controls were recruited study, then their plasma samples collected...
Long non-coding RNA KQT-like subfamily, member 1 opposite strand/antisense transcript (KCNQ1OT1) could regulate lipid metabolism, vascular smooth muscle cell function, inflammation, and atherosclerosis. This study aimed to evaluate whether lncRNA KCNQ1OT1 serve as a biomarker for reflecting coronary heart disease (CHD) patients' situation prognosis.LncRNA expression was determined in peripheral blood mononuclear cells from 267 CHD patients, 50 controls (DCs) (unexplained chest pain), healthy...
Panvascular diseases are a group of vascular system diseases, mainly including the heart, brain, neck, and other parts lesions. As non-pharmacological intervention, exercise therapy could prevent treat diseases. However, few bibliometric analyses in disease exist. This study aimed to analyze trends hotspots over past decade provide insights into latest state art global research, thereby contributing further research field. We systematically searched Web Science Core Collection (WOSCC) for...