A5008402542- Genomics, phytochemicals, and oxidative stress
- Inflammatory Bowel Disease
- Autophagy in Disease and Therapy
- Skin Protection and Aging
- Spatial Neglect and Hemispheric Dysfunction
- Migraine and Headache Studies
- Mechanisms of cancer metastasis
- Infective Endocarditis Diagnosis and Management
- Social and Demographic Issues in Germany
- NF-κB Signaling Pathways
- Acute Ischemic Stroke Management
- Helicobacter pylori-related gastroenterology studies
- Innovative Teaching Methodologies in Social Sciences
- Antimicrobial Peptides and Activities
- Antioxidant Activity and Oxidative Stress
- Skin and Cellular Biology Research
- Infant Health and Development
- Pericarditis and Cardiac Tamponade
- Polyomavirus and related diseases
- Drug Transport and Resistance Mechanisms
- Autoimmune and Inflammatory Disorders Research
- Neurosurgical Procedures and Complications
- Pregnancy and Medication Impact
- Microscopic Colitis
- Cardiac Valve Diseases and Treatments
Martin Luther University Halle-Wittenberg
2019
Medical University of Vienna
2008-2015
Robert Bosch (Germany)
2012
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology
2010
University of Tübingen
2010
Cerner (United States)
2009
Istanbul Florence Nightingale Hospital
2000
The family of the organic anion transporting polypeptides forms an increasing group uptake transport proteins with a wide substrate spectrum. Although expression some members this group, such as polypeptide (OATP)-A or C, is limited to special tissues (such liver brain), 2B1 (OATPB/SLCO2B1) expressed in many organs, including liver, placenta, mammary gland, brain, and intestine. However, little known about its function those because only number compounds, dehydroepiandrosterone-sulfate...
5-aminosalicylate (5-ASA) raises levels of 6-thioguanine nucleotides (6-TGN), the active metabolites thiopurines such as azathioprine (AZA). Changes in each individual TGN - 6-thioguanosine mono-, di- and triphosphate (6-TGMP, 6-TGDP, 6-TGTP) 6-methylmercaptopurine ribonucleotides (6-MMPR) after 5-ASA are not known.Effects increasing doses on AZA were investigated prospectively 22 patients with inflammatory bowel disease 4-week study periods. Patients started 2 g daily, then increased to 4...
Antimicrobial peptides (AMPs), an important part of the innate immune system, are crucial for defense against invading microorganisms. Whereas AMPs have been extensively studied in adult skin, little is known about impact developing human skin. We therefore compared expression and regulation fetal, neonatal, keratinocytes (KCs) vitro. The constitutive β-defensin-2 (HBD-2), HBD-3, S100 protein family members, cathelicidin was significantly higher KCs from fetal skin than postnatal capacity to...
6-Thioguanine nucleotides are the sum of 6-thioguanosine 5'-monophosphate (TGMP), -diphosphate (TGDP), and -triphosphate (TGTP) representing essential metabolites involved in drug action thiopurines. Elevated levels TGDP have been associated with poor response to azathioprine therapy patients inflammatory bowel disease. The conversion TGTP is supposed be catalyzed by nucleoside diphosphate kinase (NDPK). aim this work was investigate simultaneously individual phosphate NDPK activity red...
To evaluate the effects of an intervention using robot device PARO on visuospatial hemineglect and activities daily living, its acceptance during stroke rehabilitation. is interactive robotic toy with appearance a baby seal, which can move, produce sounds, react to speech touch.A randomized controlled trial.Hospital for neurorehabilitation.Patients above 60 years old who have suffered their first within previous three months left (n = 39).The group 21) was exposed over period two weeks,...