A5042250848- Cerebrospinal fluid and hydrocephalus
- Epilepsy research and treatment
- Fetal and Pediatric Neurological Disorders
- Vascular Malformations Diagnosis and Treatment
- Pharmacological Effects and Toxicity Studies
- Neurosurgical Procedures and Complications
- Child Abuse and Related Trauma
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Intracerebral and Subarachnoid Hemorrhage Research
- Genetics and Neurodevelopmental Disorders
- Functional Brain Connectivity Studies
- Intracranial Aneurysms: Treatment and Complications
- Meningioma and schwannoma management
- Heavy Metal Exposure and Toxicity
- Moyamoya disease diagnosis and treatment
- Reproductive Health and Technologies
- Neonatal and fetal brain pathology
- Spinal Dysraphism and Malformations
- Neurofibromatosis and Schwannoma Cases
- Neuroblastoma Research and Treatments
- Restraint-Related Deaths
- EEG and Brain-Computer Interfaces
- Head and Neck Surgical Oncology
Hôpital Necker-Enfants Malades
2013-2024
Assistance Publique – Hôpitaux de Paris
2013-2024
Université Paris Cité
2013-2024
University of South Florida
2013-2024
Pfizer (France)
2024
Inserm
1995-2023
Institut des Maladies Génétiques Imagine
2023
Florida State University
2022
Hospices Civils de Lyon
2020
Institute of Avian Research
2020
The authors undertook a study to evaluate the effectiveness of endoscopic third ventriculostomy in management hydrocephalus before and after surgical intervention for posterior fossa tumors children.Between October 1, 1993, December 31, 1997, total 206 consecutive children with underwent surgery at Hĵpital Necker-Enfants Malades Paris. Excluded were 10 patients whom shunts had been placed referring hospital. medical records neuroimaging studies remaining 196 reviewed categorized into three...
The authors have previously described less activation of left speech-related temporal areas in adults with autism when listening to speech-like sounds than normal adults. Here, they investigated whether this abnormal cortical processing was also present children primary autism.Regional cerebral blood flow measured positron emission tomography after premedication 11 autistic and six nonautistic mentally retarded during rest while were sounds.As adults, direct comparison between the two groups...
Several types of glioneuronal tumors are known to induce intractable partial seizures in children and adults. The most frequent dysembryoplastic neuroepithelial (DNETs) gangliogliomas. We report here a new clinicopathological entity within the spectrum observed 10 who underwent surgery for refractory epilepsy. These demonstrate unique, pathognomonic histological pattern specific appearance at magnetic resonance imaging (MRI). striking neuropathological feature is an angiocentric polarity...
Chemistry educators have a responsibility to teach students about the essential role field of chemistry has in sustainable future for planet. Chemical products, such as pharmaceuticals, plastics, electronics, agrochemicals, and building materials, all benefit society yet unintended consequences resulting from production use these products compel chemists develop new technologies which minimize their harm. The Committee on Professional Training (CPT)'s recently adopted Supplement "Green...
Cerebellar astrocytomas are benign tumors of childhood known to be associated with excellent long-term survival in patients whom complete surgical resection is possible. However, the roles other factors--clinical, radiological, histological, and therapeutic--in patient, tumor recurrence, patient outcome remain imprecise. The goal this study was examine these factors their relationships.To clarify issues a retrospective review conducted 168 children who were surgically treated for cerebellar...
The clinical relevance of MR scanning in children with autism is still an open question and must be considered light the evolution this technology. MRI was judged to insufficient value included standard evaluation according guidelines American Academy Neurology Child Society 2000. However, statement based on results obtained from small samples patients and, more importantly, mostly sequences. Our main objective evaluate prevalence brain abnormalities a large group non-syndromic autistic...
Childhood intracerebral hemorrhage is mainly attributable to underlying brain arteriovenous malformations (bAVMs). Multimodal treatment options for bAVMs include microsurgery and embolization, allowing an immediate cure, radiosurgery, entailing longer obliteration times. Follow-up data on pediatric ruptured are scarce, making it difficult assess the risk of subsequent hemorrhage. Our aim was clinical angiographic outcome analyze factors rebleeding during after combined bAVMs.A prospectively...
Abstract Epilepsy presurgical investigation may include focal intracortical single-pulse electrical stimulations with depth electrodes, which induce cortico-cortical evoked potentials at distant sites because of white matter connectivity. Cortico-cortical provide a unique window on functional brain networks they contain sufficient information to infer dynamical properties large-scale connectivity, such as preferred directionality and propagation latencies. Here, we developed biologically...
The incidence of epilepsy among children with hydrocephalus and its relation to shunts their complications, raised intracranial pressure (ICP), developmental outcome are explored in a retrospective study.The authors studied series 802 due varying causes, who were treated by ventriculoperitoneal shunt placement between 1980 1990, mean follow-up period 8 years. Patients had tumoral those whose files lacked significant data excluded. Data extracted from medical records, including history the...
Fetal valproate syndrome affects one in 10 children born to mothers who ingest sodium regularly during pregnancy. It has been described as producing a combination of typical dysmorphic features and major organ system anomalies. Trigonocephaly is caused by premature fusion the metopic suture not previously feature syndrome. The authors reviewed cases 2,220 with craniosynostosis examine effect maternal use on fetus.Case files all were reviewed. type severity each patient's was assessed....
Object The authors sought to analyze the success rate of surgery in management medically intractable epilepsy children with Sturge–Weber syndrome and determine whether extent timing affected seizure developmental outcomes. Methods performed a retrospective review 27 who underwent at their institution for resistant epilepsy, they examined outcomes regard control neuropsychological development. Seventeen (63%) experienced onset when were younger than 1 year age. These patients significantly...
The authors' aim in this study was to review their experience the use of indirect revascularization alone a series 14 children with moyamoya disease, which numerous bur holes and arachnoid openings were made over each affected hemisphere.Revascularization through multiple performed (mean age at diagnosis 6.5 years [range 3-15 years]) who suffered from progressive disease. authors surgery total 24 hemispheres during 18 procedures. Ten underwent bilateral hole procedures, three unilateral...
Surgery in children with epilepsy is a new, evolving field. The important practical issues have been to define strategies for choosing the most suitable candidates and type optimal timing of surgery. This study was undertaken elucidate these points.To identify factors that correlated outcome, authors analyzed series 200 (aged 1-15 years (mean 8.7 years) who underwent surgery between 1981 1996 at Hôpital Necker-Enfants Malades. In 171 cases (85.5%) medically refractory associated focal...
Suprasellar arachnoid cysts (SAC) represent between 9% and 21% of pediatric cysts. Recent improvements in magnetic resonance imaging, as well increasing prenatal diagnosis, have allowed more precise knowledge follow-up.To describe a novel classification SAC.We present 35 cases SAC treated 1996 2014. Patient records imaging studies were reviewed retrospectively to assess symptomatology, radiological findings, treatment, long-term follow-up.Fourteen diagnosed prenatally (39%). We observed 15...
<h3>BACKGROUND AND PURPOSE:</h3> The severity of Moyamoya disease is generally scaled with conventional angiography and nuclear medicine. Arterial spin-labeling MR imaging now acknowledged for the noninvasive quantification cerebral blood flow. This study aimed to analyze CBF modifications statistical parametric mapping arterial in children undergoing an operation disease. <h3>MATERIALS METHODS:</h3> We included 15 treated by indirect revascularization multiple burr-holes between 2011 2013....
The COVID-19 pandemic and the containment mitigation measures taken were feared to be associated with increased child abuse.
Alterations in autonomic control of cardiac activity epileptic patients have been reported by several studies the past, and both ictal interictal modifications heart rate regulation described. can play an important role sudden unexplained death with epilepsy (SUDEP). However, presence specific changes variability (HRV) during sleep, not correlated seizures, has assessed children epilepsy; for this reason, we evaluated features function sleep without epileptiform electroencephalogram (EEG) a...
Five children presented in the first months of life with progressive megalencephaly and leukodystrophy characterized by diffuse swelling white matter, cystic cavitations frontal temporal lobes, a slow course contrasting intensity leukodystrophic process. Four had epilepsy. Two were brothers three consanguineous parents. No metabolic defect was detected. The clinical magnetic resonance imaging features are similar to those patients previously reported. These five new cases add arguments...