A5100712567- Biofield Effects and Biophysics
- Acupuncture Treatment Research Studies
- Heart Rate Variability and Autonomic Control
- Traditional Chinese Medicine Studies
- Complementary and Alternative Medicine Studies
- Cardiac Health and Mental Health
- Cancer survivorship and care
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- Sphingolipid Metabolism and Signaling
- Stoma care and complications
- Cancer Mechanisms and Therapy
- Titanium Alloys Microstructure and Properties
- Health and Wellbeing Research
- Cell death mechanisms and regulation
- Medicinal Plant Pharmacodynamics Research
- Ginseng Biological Effects and Applications
- Laser-Ablation Synthesis of Nanoparticles
- Protein Structure and Dynamics
- Cellular Mechanics and Interactions
- 3D Printing in Biomedical Research
- Cytokine Signaling Pathways and Interactions
- Enzyme Structure and Function
- Erythrocyte Function and Pathophysiology
- Developmental Biology and Gene Regulation
Chongqing Medical University
2025
Chongqing Medical and Pharmaceutical College
2025
Guangzhou University of Chinese Medicine
2014-2024
Guangdong Provincial Hospital of Traditional Chinese Medicine
2024
Affiliated Hospital of North Sichuan Medical College
2024
University of Michigan
2021-2024
Shanxi Medical University
2024
Muskingum University
2017
China Pharmaceutical University
2012-2014
Virginia Commonwealth University
2012-2014
Linker structures are a crucial component of proteolysis-targeting chimeras (PROTACs) and have traditionally been designed based on empirical methods, which presents significant challenges in the development PROTACs. Current optimization strategies typically focus reducing number rotatable bonds linker to limit conformational freedom. However, this approach overlooks complexity target protein degradation process. Retrospective analyses suggest that merely adjusting is insufficient control...
Cholangiocarcinoma (CCA) is an often fatal primary malignancy of the intra- and extrahepatic biliary tract that commonly associated with chronic cholestasis significantly elevated levels conjugated bile acids (CBAs), which are correlated duct obstruction (BDO). BDO has also recently been shown to promote CCA progression. However, whereas there increasing evidence linking abnormal acid profiles development progression, specific mechanisms by may be acting cholangiocarcinogenesis invasive...
The purpose of this study was to examine the effects Baduanjin sequential therapy (BST) on quality life and cardiac function in patients with AMI after PCI.96 PCI were randomly assigned as subjects two groups: BST group who received 24 weeks training control no training.The methods used included changes SF-36 subscales, measures left ventricular ejection fraction (LVEF), N-terminal pro-B-type natriuretic peptide (NT-pro-BNP), body mass index (BMI), abdominal circumference.Of 96 participants,...
Rationale: Seated-Baduanjin as adjuvant rehabilitation treatment in a patient with Dysfunctional ventilatory weaning response(DVWR) is extremely rare, and we report case of patient's exercise who suffered from DVWR. Patient concerns: A 62-year-old was admitted for dyspnea more than month after surgery. Diagnoses: On arrival, the conscious but anxious, he had difficulty breathing. When attempting to disconnect ventilator, autonomous respiration > 25 times /min, heart rate 120 /min. He rely on...
Abstract Traditional Chinese medicine assigns individuals into different categories called “constitutions” to help guide the clinical treatment according subjective physiologic, psychologic analyses, large-scale observations, and epidemiologic studies. To further explore more objective expressions of constitutions, antibody microarrays were used analyze serologic protein profiles two a balanced (or healthy) constitution (BC) dampness (DC) comprising phlegm-dampness damp-heat constitutions....
Micro Retail Enterprises (MREs) are ubiquitous in cities and countryside of China.They however generally ignored the literature lumped with Small Medium (SMEs).MREs unique a number key ways how they have responded to slowing economy China has yet be examined.This paper seeks shed light on MREs dealt changes China's economy.Not all sectors same "new normal" growth during past year.The authors conducted 1,440 surveys seven gathered data access bank loans, acceptance credit cards, which...
<title>Abstract</title> Symptom cluster and quality of life are negatively associated, but the prospective inter-relationship between them were unknown,which may provide a mechanism insight for symptom management. A longitudinal study was conducted among 140 patients who undergoing laparoscopic-assisted sphincter-preserving surgery rectal cancer 2021 to 2022. We investigated associations change with trajectories life. These assessed clusters at specific time points: 2 weeks (T1), 1 month...
Objective: Titanium implants are widely used in surgeries for their biocompatibility and mechanical properties. However, excessive titanium particle release can cause implant failure. This study explores Atomic Layer Deposition (ALD) to coat commercially pure (Cp-Ti) with TiO 2 , aiming improve its frictional corrosion resistance while reducing release. By comparing films varying ALD cycle numbers, we assess surface properties, release, friction, performance, providing insights into...
Background Constitution is a valuable part of traditional Chinese medicine theory; it defined as the internal foundation for occurrence, development, transformation and outcome diseases, has its characteristic gut microbiota. Previous study showed that deficiency constitution was related to lower Hb counts. However, no research examined how alterations in microbiome induced by may increase tendency anemia. Methods We used multiomics strategy identify quantify taxonomies compounds found under...
Although it is generally recognized that symptom clusters and quality of life are related, major ambiguity arises from the difficulty in determining their causal relationship. The present study aimed to investigate longitudinal relationships between life. 128 patients with rectal cancer Nanchong City, Sichuan Province who underwent laparoscopic anus-preserving surgery completed 4 follow-up visits, survey time point 2 weeks after (T1), 1 month (T2), 3 months (T3), 6 (T4). We used Anderson...
Abstract Background: S i nce December 2019, an epidemic caused by novel coronavirus(2019-nCoV) infection has occurred unexpectedly in China. Because of the sudden nature outbreak and infectious power virus, it will inevitably cause people anxiety other stress reactions. Previous studies showed that Baduanjin exercise was effective for insomnia. The purpose this study to evaluate potential benefits on insomnia COVID-2019 patients. Methods: This is a Case-Control Study. patients including 39...
Our previous studies suggest that the HIV protease inhibitor (PI)‐induced ER stress and inflammatory response in macrophages represents an important cellular mechanism of highly active anti‐retroviral therapy (HAART)‐induced dyslipidemia atherosclerosis. Raltegravir is first member newest class anti‐HIV drugs, integrase inhibitor. recent indicate raltegravir has less hepatic toxicity could prevent PI‐induced dysregulation lipid metabolism by inhibiting hepatocytes. However, whether also able...
Objective To evaluate the satisfaction of conscious patients in ICU, and discuss how to promote efficiently. Methods All matched ICU from January December 2015 were included self-designed questionnaire scales used investigate these before their discharging ICU.The results, reliability validity analyzed. Results The overall Cronbach's α Coefficient was 0.931, split-half 0.887, construct KMO(MSA) 0.863, differences statistically significant.The analysis results showed that...
<sec> <title>BACKGROUND</title> Acute myocardial infarction (AMI) is a serious type of coronary artery disease (CAD) with the potential for substantial morbidity and mortalit. Percutaneous intervention (PCI) an effective treatment. However, most patients still suffer from angina pectoris, anxiety, depression reduced cardiac function after PCI. </sec> <title>OBJECTIVE</title> The purpose this study was to examine effects Baduanjin sequential therapy (BST) on quality life in AMI...