A5101995595- Electrospun Nanofibers in Biomedical Applications
- Plant Virus Research Studies
- Nerve injury and regeneration
- Tissue Engineering and Regenerative Medicine
- Photosynthetic Processes and Mechanisms
- RNA Interference and Gene Delivery
- Toxin Mechanisms and Immunotoxins
- Graphene and Nanomaterials Applications
- Liver physiology and pathology
- CRISPR and Genetic Engineering
- Bone Metabolism and Diseases
- Organ Transplantation Techniques and Outcomes
- Plant Genetic and Mutation Studies
- MicroRNA in disease regulation
- Immunotherapy and Immune Responses
- DNA Repair Mechanisms
- Advanced biosensing and bioanalysis techniques
- Hemostasis and retained surgical items
- Virus-based gene therapy research
- Epigenetics and DNA Methylation
- Wound Healing and Treatments
- interferon and immune responses
- Genomics and Chromatin Dynamics
- Silk-based biomaterials and applications
- Ferroptosis and cancer prognosis
Guangdong Ocean University
2023-2025
Affiliated Hospital of Youjiang Medical University for Nationalities
2024
University of Birmingham
2024
Shenzhen Institutes of Advanced Technology
2019
Chinese Academy of Sciences
2019
Jinan University
2019
University of Hong Kong
2018
Southwest Jiaotong University
2011-2012
Deep or chronic skin wounds are difficult to heal spontaneously due the lack of scaffold guide cell growth and reduced levels activities endogenous factors. Emulsion electrospinning process integrated with DNA condensation techniques indicated potentials gradually release DNA, but no attempt has been made clarify advantages in promoting tissue regeneration wound recovery. In this study, polyplexes basic fibroblast factor-encoding plasmid (pbFGF) poly(ethylene imine) were incorporated into...
Electrospun fibrous scaffolds have been extensively used as cell-supporting matrices or delivery vehicles for various biomolecules in tissue engineering. Biodegradable with tunable degradation behaviors are favorable resorbable replacements. In nerve engineering, of growth factors (GFs) such factor (NGF) and glial cell line-derived neurotrophic (GDNF) from can be to promote peripheral repair. this study, using the established dual-source dual-power electrospinning technique, bicomponent...
To ensure timely duplication of the entire eukaryotic genome, thousands replication machineries (replisomes) act on genomic DNA at any time during S phase. In final stages this process, replisomes are unloaded from chromatin. Unloading is driven by polyubiquitylation MCM7, a subunit terminated replicative helicase, and processed p97/VCP segregase. Most our knowledge termination comes model organisms, little known about how process executed regulated in human somatic cells. Here we show that...
Scaffolds capable of providing dual neurotrophic factor (NTF) delivery with different release kinetics, spatial NTFs at loci and topographical guidance are promising for enhanced peripheral nerve regeneration. In this study, we have designed fabricated multi-layered aligned-fiber scaffolds through combining emulsion electrospinning, sequential electrospinning high-speed (HS-ES) to modulate the behavior glial cell line-derived growth factor(GDNF) (NGF). GDNF NGF were incorporated into...
Abstract High photosynthetic efficiency is the basis of high biomass and harvest index in castor ( Ricinus communis L.). Understanding genetic law traits will facilitate breeding for efficiency. In this study, dynamic QTL mapping was performed with populations F 2 BC 1 derived from parents significant difference net rate (Pn) at 3 stages, order to reveal structure traits. population, 26 single-locus QTLs were identified, including 3/3/1 (the number stage I/II/III, same below), 1/2/0, 1/2/2,...
Electrospun fibers are excellent delivery vehicles enabling a sustained release of growth factors to elicit favorable cell responses and increasingly used in tissue engineering. Scaffolds with specific physical/topographical features can also guide migration maturation. Therefore, factor-loaded electrospun scaffolds designed topography promising for regeneration. In this investigation, aligned-fiber composed poly(lactic-co-glycolic acid) nanofibers incorporating glial line-derived factor...
The major curative remedy for advanced liver failure is hepatic transplantation. However, the conventional medicine still shows limitations and obstacles regeneration. Importantly, it unclear whether we can get a rapid high efficacy platform to facilitate reprogram capability. main work of this study was develop nanomedicine-based gene-delivery novel nanoparticles (NNPs) efficiently function recovery.In study, studied feasibility efficiency NNP produced multiple abilities NNPs potential gene...