A5048121358- Quantum and electron transport phenomena
- Semiconductor Quantum Structures and Devices
- Physics of Superconductivity and Magnetism
- Graphene research and applications
- Topological Materials and Phenomena
- 2D Materials and Applications
- 3D Printing in Biomedical Research
- Quantum Information and Cryptography
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- MXene and MAX Phase Materials
- Liver physiology and pathology
- Natural product bioactivities and synthesis
- Advancements in Semiconductor Devices and Circuit Design
- Bioactive Natural Diterpenoids Research
- Advanced Photocatalysis Techniques
- Electrochemical sensors and biosensors
- Phytochemistry and Biological Activities
- Advanced Thermoelectric Materials and Devices
- Cell death mechanisms and regulation
- Advanced Semiconductor Detectors and Materials
- Histone Deacetylase Inhibitors Research
- Ethnobotanical and Medicinal Plants Studies
- Alkaloids: synthesis and pharmacology
- Medicinal Plant Pharmacodynamics Research
Beijing Academy of Quantum Information Sciences
2019-2025
Dalian University
2024
Dalian University of Technology
2024
Beijing Zhongke Science and Technology (China)
2023
China University of Mining and Technology
2022
Kunming University of Science and Technology
2017-2021
Kunming Medical University
2020
Jinan University
2020
Peking University
2017-2019
Zhejiang Provincial People's Hospital
2018
Abstract Superconducting diodes, characterized by the nonreciprocal supercurrent flow, have gained significant attention for their potential in dissipationless electronics. This study presents a superconducting quantum interference device (SQUID) composed of two Al-InSb nanosheet Josephson junctions. Utilizing prepatterned local backgates, we achieve gate- and flux-tunable diode with controllable efficiency both amplitude sign. Numerical simulations attribute effect to higher harmonics...
The maintenance of hepatocyte phenotype and functions remains as a great challenge in the generation functional liver tissue vitro model for drug metabolism studies. use coculture systems plays essential roles establishment cell–cell cell–extracellular matrix communications similar to native tissues. In current study, micropatterned electrospun fibrous mats were created load hepatocytes, fibroblasts, endothelial cells (ECs), which precisely assembled establish their spatially controlled...
Trichostatin A (TSA) possess histone deacetylase (HDAC) inhibitory potential, can reverse the deactivation of tumor suppressor genes and inhibit cell proliferation. We evaluated effect TSA on HDAC expression, proliferation, cancer stem cells (CSCs) activities in pancreatic ductal adenocarnoma (PDAC) cells. The PDAC lines MiaPaCa-2 PANC-1 were distinctly sensitive to TSA, with enhanced apoptosis, compared SAHA. or SAHA inhibited vimentin, HDACs 1, 7 8, upregulated E-cadherin mRNA protein...
Abstract Van der Waals magnets have emerged as a fertile ground for the exploration of highly tunable spin physics and spin-related technology. Two-dimensional (2D) magnons in van are collective excitation spins under strong confinement. Although considerable progress has been made understanding 2D magnons, crucial magnon device called valve, which signal can be completely repeatedly turned on off electrically, yet to realized. Here we demonstrate such valves based antiferromagnetic...
Spatial arrangement of multiple cell types plays a critical role in maintaining the viability cells and functionality tissues. Micropatterning has been used to fabricate scaffolds modulate distribution, growth, functions for reconstructing anisotropy native In current study, glass substrate patterned with an electrically conductive circuit was prepared by lithography as collector electrospinning. Densely packed fibers were deposited on top silver strips fibrous mats obtained distinct ridge...
Colorectal cancer (CRC) is one of the most prevalent malignancies in world and developed drug resistance has represented challenging tasks for management. The current therapeutic regimens may select enrich stem-like cells (CSCs) resulting increased against treatment, metastatic potential mortality. Regorafenib a multi-kinase inhibitor, an FDA-approved last-of-line treatment patients with chemo-refractory CRC. However, regorafenib's effects on CSCs have not been fully elucidated.Here, we two...
Abstract The observation of Josephson diode effect (JDE) is reported in hybrid devices made from semiconductor InAs nanosheets and superconductor Al contacts. By applying an in‐plane magnetic field ( B xy ), non‐reciprocal superconducting switching current as well retrapping are detected. strength the JDE depends on angle between bias I b reaching its maximum when ⊥ dropping to nearly zero ∥ . Additionally, efficiency tunable via electrostatic gate with a complete suppression at certain...
P-glycoprotein (P-gp) plays a significant role in multi-drug resistance (MDR) of cancer cells, resulting the failure chemotherapy. Lathyrane diterpene was class promising MDR modulator. The phytochemical investigation on seeds Euphorbia lathyris L. aff ;orded four new lathyrol-type diterpenoids (1-4), together with seventeen known ones (5-23). structures these compounds were elucidated by using 1D and 2D NMR spectroscopy. All evaluated reversing activity HepG2/ADR cells. Compounds 2-4, 7-9,...
Under certain symmetry-breaking conditions, a superconducting system exhibits asymmetric critical currents, dubbed the ``superconducting diode effect.'' Recently, systems with ideal efficiency or unidirectional superconductivity have received considerable interest. In this work, we report study of Al-InAs nanowire-Al Josephson junctions under microwave irradiation and magnetic fields. We observe an enhancement effect driving, featured by horizontal offset zero-voltage step in voltage-current...
We report the observation of Josephson diode effect (JDE) in hybrid devices made from semiconductor InAs nanosheets and superconductor Al contacts. By applying an in-plane magnetic field ($B_{\mathrm{xy}}$), we detect non-reciprocal superconducting switching current as well retrapping current. The strength JDE depends on angle between bias ($I_{\mathrm{b}}$), reaching its maximum when $B_{\mathrm{xy}} \perp I_{\mathrm{b}}$ dropping to nearly zero $B_{\mathrm{xy}}\parallel I_{\mathrm{b}}$....
Abstract Strong band engineering in two-dimensional (2D) materials can be achieved by introducing moiré superlattices, leading to the emergence of various novel quantum phases with promising potential for future applications. Presented works create patterns have been focused on a twist embedded inside channel or between and substrate. However, effects substrate unaligned are much less explored. In this work, we report realization superlattice multi-Dirac cones coexistence main Dirac cone...
The establishment of a reliable in vitro liver model for drug screening remains challenging with respect to tethering the growth hepatocyte spheroids and adapting current high-throughput system. In study, short fibers are utilized as scaffolds generation size-controlled that recapitulate vivo hepatic phenotypes functions. spheroid formation is modulated by length galactose/RGD grafts fibers, 50 μm long motivate optimal function. Short distribute throughout entire form compact spheroids....
A series of Y 1.55 Ti 2 O 7 :0.45 Eu 3+ phosphors with orange‐red emission under near ultraviolet excitation were prepared in solid‐state reaction NH 4 Cl , F H 3 BO LiF and NaF as flux, respectively. Comparative studies showed that flux could not only modify the morphology grain size, but have a significant influence on spatial distribution activator across host. best one among five materials, helped phosphor particles to sphere‐like morphology, micrometer‐level size well uniform activator,...
It remains as a great challenge to maintain the viability and functions of hepatocytes in vitro, construction various scaffold materials establishment hepatocyte coculture systems are essential for reconstruction engineered liver devices. In our previous study, micropatterned electrospun fibrous mats were developed control cellular behaviors, indicating that cell growth extracellular matrix deposition confined patterned regions. current primary rat fibroblasts was established on scaffolds...
Three new compounds (1 - 3), including a sesterterpenoid, aspterpenacid C (1), with an unusual 5/3/7/6/5 pentacyclic skeleton, together seven known ones (4 10), were isolated from the ethanol extract of traditional Chinese medicinal plant Swertia bimaculata. Their structures elucidated on basis methods spectroscopic NMR, MS, and computational chemistry. The structure 1 was further confirmed by single-crystal X-ray diffraction analysis. Compounds 10 tested for activities inhibition nitric...
Much effort has been devoted to the electronic properties of relatively thick $\mathrm{Zr}{\mathrm{Te}}_{5}$ crystals, focusing on their three-dimensional topological effects. Thin other hand, were much less explored experimentally. Here we present detailed magnetotransport studies few-layer devices, in which electron-electron interactions and weak antilocalization are observed. The coexistence two effects manifests itself corroborating evidence presented temperature magnetic field...
We report an experimental study of a 1D quintuple-quantum-dot array integrated with two charge sensors in InAs nanowire. The device is studied by measuring double quantum dots formed consecutively the array, and corresponding stability diagrams are revealed both direct current measurements sensor signals. one-dimensional then tuned up, its configurations fully mapped out sensors. energy level each dot can be controlled individually using virtual gates. After that, four selected to form dots,...