A5082187438- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Respiratory Support and Mechanisms
- Natural Antidiabetic Agents Studies
- Immune Response and Inflammation
- Phytochemicals and Antioxidant Activities
- Neonatal Respiratory Health Research
- Natural product bioactivities and synthesis
- Bone Metabolism and Diseases
- Wnt/β-catenin signaling in development and cancer
- Hippo pathway signaling and YAP/TAZ
- Hedgehog Signaling Pathway Studies
- Tumors and Oncological Cases
- Phytochemical Studies and Bioactivities
- Ovarian function and disorders
- Bioactive natural compounds
- Respiratory and Cough-Related Research
- Ethics and Legal Issues in Pediatric Healthcare
- Epigenetics and DNA Methylation
- Diverse Scientific Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Helicobacter pylori-related gastroenterology studies
- Vitamin C and Antioxidants Research
- Ethnobotanical and Medicinal Plants Studies
Islamia University of Bahawalpur
2019-2025
University of Alabama at Birmingham
2024-2025
Zhejiang University
2016-2024
Sir Run Run Shaw Hospital
2021
Bahauddin Zakariya University
2015-2019
University of Faisalabad
2014-2019
National Medical Products Administration
2017-2019
The First People's Hospital of Wenling
2017
Children's Hospital of Zhejiang University
2017
Polycystic ovarian syndrome is a multidisciplinary endocrinopathy of reproductive-aged women that provokes insulin resistance, hyperandrogenism, cardiovascular problems, obesity, and menstrual complications. The present study was designed to investigate the effectiveness ethanolic extract Fagonia indica in letrozole-induced PCOS young adult female rats. HPLC carried out find phenolic flavonoid content indica. Twenty-five rats were taken initially divided into two groups: group I (control...
Dracaena reflexa, a traditionally significant medicinal plant, has not been extensively explored before for its phytochemical and biological potential. The present study was conducted to evaluate the bioactive phytochemicals in vitro activities of D. perform silico molecular docking validation reflexa. were assessed by preliminary testing, total contents, GC-MS analysis. For evaluation, antioxidant (DPPH, ABTS, CUPRAC, ABTS), antibacterial, thrombolytic, enzyme inhibition (tyrosinase...
Traditional medicine uses the roots and rhizomes of Polygonum bistorta L. (Polygonaceae) to treat cough, bronchitis, other respiratory infections. Our goal was gain insights into lung protective effects P. against lipopolysaccharide-induced acute injury in rats, along with possible mechanism(s). The outcomes revealed deliberate quantities total phenolic flavonoid contents 156.2 ± 5.13 GAE/g 179.45 2.08 mg QE/g, respectively. Crude extract possesses a maximum inhibitory potential 81.77% 0.62%...
A comparative study between methanolic extract and n-hexane fraction of Typha domingensis (Typhaceae) was conducted for the evaluation phytochemical potential, in vitro biological activities, in-silico molecular docking studies. The composition estimated by total phenolic flavonoid contents, GC–MS analysis. Several activities were performed such as antioxidant assays (ABTS, FRAP, DPPH, & CUPRAC), enzyme inhibition activity (Tyrosinase, Acetylcholinesterase Butyrylcholinesterase),...
Cdc42, a member of Rho family small guanosine triphosphatases (GTPases), is critical for cartilage development. We investigated the roles Cdc42 in osteoarthritis and explored potential mechanism underlying Cdc42-mediated articular degeneration subchondral bone deterioration. highly expressed both mouse model with surgical destabilization medial meniscus (DMM) knee joints. Specifically, genetic disruption knockdown expression, or inhibition activity robustly attenuates DMM-induced...
Bambusa arundinacea (RETZ.) Willd. is distributed in tropical regions of Pakistan, India, and China. It has been used for a long time as folk remedy cirrhosis, urinary tract ailments, various other abdominal cavity disorders. antioxidant, free-radical-scavenging, anti-inflammatory effects. The aims objectives this study were to validate the folkloric uses evaluate its nephroprotective potential on scientific grounds. Gentamycin (G.M, 40 mg/kg) was induce nephrotoxicity animal model. Two...
M2 polarized tumor-associated macrophages (TAMs) have a multifunctional role in cancer initiation, progression, metastasis, and contribute to chemotherapeutic resistance. Therefore, identifying TAMs is potential target for therapeutic intervention. The underlying mechanism that the remains primarily uncharacterized; however, only few compounds been identified inhibit macrophages. In this research, we investigated lapatinib could effectively suppress expression of IL_13-induced surface...
The Wnt/β-catenin signaling pathway appears to be particularly important for bone homeostasis, whereas nuclear accumulation of β-catenin requires the activation Rac1, a member Rho small GTPase family. aim present study was investigate role RhoA/Rho kinase (Rock)-mediated in regulation aging-associated loss. We find that Lrp5/6-dependent and Lrp5/6-independent RhoA/Rock by Wnt3a activates Jak1/2 directly phosphorylate Gsk3β at Tyr216, resulting subsequent destabilization. In line with these...
Jasminum sambac (L.) is a South Asian folkloric medicinal plant that has traditionally been used to treat cardiovascular problems. The current investigation was meticulously organized explore the pharmacological foundation for uses of J. pertaining ailments and investigate core mechanisms. Mechanistic revealed crude leaf extract produced ex-vivo vasorelaxant effects in endotheliumintact aorta ring preparation hypotensive effect recorded via pressure force transducers coupled Power Lab Data...
Human diseases are becoming more prevalent, necessitating the development of modalities to overcome challenges treating various disorders. In current research, we analyzed biomedicinal role Typha domingensis which is an important medicinal plant. The species traditionally used in treatment neurological disorders and skin malignancies. chloroform (CFTD) n-butanol fractions T. (BFTD) were subjected chemical profiling through determination total polyphenolic contents GC-MS analysis. oral...
Launaea fragilis (Asso) Pau (Family: Asteraceae) is a wild medicinal plant that has been used in the folklore as potential treatment for numerous ailments such skin diseases, diarrhea, infected wounds, inflammation, child fever and hepatic pain. This study explored chemical constitution, in-vivo toxicity, antimicrobial, antioxidant, enzyme inhibition of ethanolic extract L. (EELF). Additionally, in-silico docking studies predominant compounds were performed against in-vitro tested enzymes....
Patient satisfaction can be used to assess the quality of services provided at pharmacies. Our aim was determine level patient with pharmacy and related factors community pharmacies located in Punjab, Pakistan.A questionnaire-based cross-sectional study conducted from May 2021 July by administering questionnaire patients using stratified random sampling method. Survey instrument comprised 4 sections including demographics, towards provision facilities, information, their accessibility...