A5102917094- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Retinal Development and Disorders
- Retinal and Macular Surgery
- Ocular Surface and Contact Lens
- Retinal and Optic Conditions
- Retinopathy of Prematurity Studies
- Intraocular Surgery and Lenses
- Corneal Surgery and Treatments
- Neonatal Respiratory Health Research
- Ophthalmology and Eye Disorders
- Cerebrovascular and genetic disorders
- Ocular Oncology and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Ocular Infections and Treatments
- S100 Proteins and Annexins
- Systemic Lupus Erythematosus Research
- Photoreceptor and optogenetics research
- Ocular and Laser Science Research
- Blood Coagulation and Thrombosis Mechanisms
- Allergic Rhinitis and Sensitization
- Vascular Malformations Diagnosis and Treatment
- Angiogenesis and VEGF in Cancer
Osaka University
2016-2025
Gifu University
2025
Osaka Women's and Children's Hospital
2024
Frontier Medical College
2024
Osaka University Hospital
2014-2024
RELX Group (United States)
2009
Mayo Clinic in Florida
2009
Abstract Intravitreal injection of aflibercept (IVA) has successfully treated polypoidal choroidal vasculopathy (PCV), and polyp morphology is an important indicator treatment efficacy. However, many studies have not reported the presence or absence regression outcomes, few reduction outcomes in cases with residual polyps. We retrospectively measured area on indocyanine green angiography images before after IVA loading phase investigated polyps 81 eyes PCV IVA. relationship between complete...
Introduction: Proliferative vitreoretinopathy (PVR) is a condition in which proliferation forms after rhegmatogenous retinal detachment (RRD) surgery or old RRD, and sometimes, PVR can occur under silicone oil (SO). Here, we report 2 cases of evaluated preoperative B-scan images SO using ultra-widefield swept-source OCT (UWF-SS-OCT). Case Presentation: The first case was 61-year-old male who presented with tamponade multiple pars plana vitrectomies (PPVs) at the previous hospital, second...
Glaucoma is a series of irreversible and progressive optic nerve degenerations, often accompanied by astrocyte remodeling as the disease progresses, process that insufficiently understood. Here, we investigated morphology retinal head (ONH) astrocytes under mechanical stress, explored whether specific phase present precedes remodeling. A mouse model transient ocular hypertension (OHT) an in vitro cell stretch were established to mimic pathological conditions increased intraocular pressure...
Purpose: To compare the visual outcomes of intravitreal (IVT) aflibercept with pneumatic displacement vs without for submacular hemorrhage (SMH) associated polypoidal choroidal vasculopathy (PCV). Methods: This retrospective study assessed patients SMH PCV who were treated and gas (aflibercept+gas group) or alone (monotherapy group). Patients followed at least 12 months, best-corrected acuity (BCVA) months primary outcome measure. Results: Forty-seven eyes 47 retrospectively analyzed from...
Abstract Rapid and precise identification discrimination of causative pathogens are required in the treatment infectious diseases. Quantitative real-time polymerase chain reaction is used to detect identify viruses before treatment. Although it an established modality, results take several hours, even well-equipped hospitals. It difficult simultaneously many pathogen types because only a single virus genome can be amplified per reaction. Recently, artificial intelligence (AI)-based nanopore...
Purpose: Detection of the exact area corneal neovascularization using slit-lamp photography is often difficult. Thus, we evaluated in patients with limbal stem cell deficiency optical coherence tomography angiography (OCTA). Methods: Five 5 eyes showing partial or total were enrolled. Three had severe scarring. 6- × 6-mm images (frontal, upper, lower, nasal, and temporal) obtained by OCTA. Slit-lamp was performed for all on same day. Results: OCTA has 2 advantages over clear demonstration...
To compare chorioretinal atrophy (CRA) progression in myopic choroidal neovascularization (mCNV) between intravitreal injections of ranibizumab (IVR) and aflibercept (IVA) the eyes with mCNV. Thirty (28 patients) treatment-naïve mCNV were included this study. IVR or IVA was administered for up to 1 year. The best-corrected visual acuity (BCVA) measured, fundus photographs autofluorescence obtained before 1, 3, 6, 12 months after initial treatment. clinical characteristics including macular...
Despite extensive exploration of potential biomarkers cardiovascular diseases (CVDs) derived from retinal images, it remains unclear how images contribute to CVD risk profiling and the results can inform lifestyle modifications. Therefore, we aimed determine performance prediction model via explicitly estimating 10 traditional factors compared with based on actual measurements.
We describe a case of fish-eye disease (FED) where the clinical features and visual function were investigated using anterior segment optical coherence tomography (OCT) quantitative measurements. A 36-year-old Japanese woman with FED presented bilateral corneal opacities complaints. Both contrast sensitivity straylight measured OCT imaging was performed. Contrast measurements revealed remarkably decreased function, despite good acuity. demonstrated homogenously hyper-reflective...
Purpose: To determine the relevance of epiretinal membranes (ERMs) in primary open-angle glaucoma (POAG) and potential risk for severity. Methods: Sixty eyes 30 patients with POAG who had a unilateral ERM were analyzed; 60 nonglaucomatous also recruited this institutional cross-sectional study. Patients underwent swept-source (SS) optical coherence tomography (OCT) imaging visual field testing. Intraindividual differences SS-OCT retinal nerve fiber layer (RNFL) disc cupping area measurements...
To compare ocular surface squamous neoplasia (OSSN) and pterygium using anterior segment optical coherence tomography angiography (AS-OCTA).Flow patterns of conjunctival vessels in patients with OSSN were investigated AS-OCTA. In case 1, slit-lamp examination a 72-year-old woman revealed an elevated lesion increased permeability fluorescein the inferior nasal conjunctiva her left eye. AS-OCTA showed markedly meandering large blood both superficial deep layers. Histopathological evaluation...
To document enlarged neovascularization elsewhere (NVE) quantitatively and morphologically using widefield swept-source (SS) OCT angiography (OCTA) with vitreoretinal interface (VRI) slab images.Retrospective, observational imaging study.The study included 46 NVE examples in 25 eyes of 21 consecutive patients who demonstrated severe proliferative diabetic retinopathy between March 2018 June 2020 at Osaka University Hospital.All underwent ophthalmologic examination, including ultra-widefield...