A5058298199- Mosquito-borne diseases and control
- Malaria Research and Control
- COVID-19 epidemiological studies
- HIV/AIDS drug development and treatment
- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Parasitic Diseases Research and Treatment
- Evolution and Genetic Dynamics
- Parasites and Host Interactions
- Mathematical and Theoretical Epidemiology and Ecology Models
Swiss Tropical and Public Health Institute
2020-2023
University of Basel
2020-2022
Abstract Due to the COVID-19 pandemic, many key neglected tropical disease (NTD) activities have been postponed. This hindrance comes at a time when NTDs are progressing towards their ambitious goals for 2030. Mathematical modelling on several NTDs, namely gambiense sleeping sickness, lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminthiases (STH), trachoma, and visceral leishmaniasis, shows that impact of this disruption will vary across diseases. Programs face...
Abstract Malaria cases can be classified as imported, introduced or indigenous cases. The World Health Organization’s definition of malaria elimination requires an area to demonstrate that no new have occurred in the last three years. Here, we present a stochastic metapopulation model transmission distinguishes between and cases, used test impact interventions setting with low ongoing case importation. We use human movement prevalence data from Zanzibar, Tanzania, parameterise model....
Malaria persists at low levels on Zanzibar despite the use of vector control and case management. We a metapopulation model to investigate role human mobility in malaria persistence Zanzibar, impact reactive detection. The was parameterized using survey data prevalence, detection, travel history. find that absence imported cases from mainland Tanzania, would likely cease persist Zanzibar. also potential intervention scenarios may lead elimination, especially through changes While we some...
Gambiense human African trypanosomiasis is a deadly disease that has been declining in incidence since the start of Century, primarily due to increased screening, diagnosis and treatment infected people. The main regimen currently use requires lumbar puncture as part diagnostic process determine stage hospital admission for drug administration. Fexinidazole new oral 1 non-severe 2 trypanosomiasis. World Health Organization recently incorporated fexinidazole into its guidelines does not...
Abstract Malaria cases can be classified as imported, introduced or indigenous cases. The World Health Organization definition of malaria elimination requires an area to demonstrate no new have occurred in the last three years. Here, we present a transmission model that incorporates human mobility and distinguishes between We test impact several interventions on Zanzibar such reactive case detection, drug administration, treating infected travellers, reduction mainland Tanzania. find...
Abstract Malaria persists at low levels on Zanzibar despite the use of vector control and case management. We a metapopulation model to investigate role human mobility in malaria persistence Zanzibar, impact reactive detection. The was parameterized using survey data prevalence, detection, travel history. find that absence imported cases from mainland Tanzania, would likely cease persist Zanzibar. also potential intervention scenarios may lead elimination, especially through changes While we...
Abstract Gambiense human African trypanosomiasis is a deadly disease that has been declining in incidence since the start of Century, primarily due to increased screening, diagnosis and treatment infected people. The main regimen currently use requires lumbar puncture as part diagnostic process determine stage hospital admission for drug administration. Fexinidazole new oral 1 non-severe 2 trypanosomiasis. World Health Organization recently incorporated fexinidazole into its guidelines does...