Xiang Ao

ORCID: 0000-0001-8851-7706
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About
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Research Areas
  • Animal Nutrition and Physiology
  • Vasculitis and related conditions
  • Meat and Animal Product Quality
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Tryptophan and brain disorders
  • Rabbits: Nutrition, Reproduction, Health
  • Chronic Kidney Disease and Diabetes
  • Renal Diseases and Glomerulopathies
  • Agriculture, Soil, Plant Science
  • Moringa oleifera research and applications
  • Aquaculture Nutrition and Growth
  • Mycotoxins in Agriculture and Food
  • Animal Behavior and Welfare Studies
  • Stress Responses and Cortisol
  • Sarcoidosis and Beryllium Toxicity Research
  • Acute Kidney Injury Research
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Garlic and Onion Studies
  • Gut microbiota and health
  • Dialysis and Renal Disease Management
  • Liver Disease Diagnosis and Treatment
  • Wheat and Barley Genetics and Pathology
  • Insect Utilization and Effects
  • Stock Market Forecasting Methods
  • Hormonal Regulation and Hypertension

Southwest University of Science and Technology
2019-2025

South China Agricultural University
2023-2025

Key Laboratory of Guangdong Province
2023-2025

Ministry of Agriculture and Rural Affairs
2023-2025

Yibin University
2024-2025

Inner Mongolia Medical University
2025

Qingdao University
2025

University of Chinese Academy of Sciences
2024

Ruijin Hospital
2024

Hunan Normal University
2024

The study was conducted to determine the effects of probiotics (Bacillus subtilis endospore and Clostridium butyricum complex) supplementation different energy nutrient densities on growth performance, digestibility, meat quality in growing-finishing pigs. A total 96 pigs with initial BW 47.50 ± 1.14 kg were used a 10-wk experiment. Pigs randomly allotted 1 4 treatments 2 × factorial arrangement levels density (low high energy, CP, Lys) 0.2% according their sex (6 pens, gilts barrows/pen)....

10.2527/jas.2009-2308 article EN Journal of Animal Science 2010-09-08

The molecular mechanisms underlying renal damage of IgA nephropathy (IgAN) remain incompletely defined. Here, single-cell RNA sequencing (scRNA-seq) was applied to kidney biopsies from IgAN and control subjects define the transcriptomic landscape at resolution. We presented a comprehensive scRNA-seq analysis human IgAN. showed for first time that mesangial cells displayed increased expression several novel genes including MALAT1, GADD45B, SOX4, EDIL3, which were related cell proliferation...

10.3389/fimmu.2021.645988 article EN cc-by Frontiers in Immunology 2021-04-16

Abstract Since December 2019, a novel coronavirus named 2019 (2019-nCoV) has emerged in Wuhan of China and spread to several countries worldwide within just one month. Apart from fever respiratory complications, acute kidney injury been observed some patients with 2019-nCoV. In short period time, angiotensin converting enzyme II (ACE2), have proposed serve as the receptor for entry 2019-nCoV, which is same severe syndrome (SARS). To investigate possible cause damage 2019-nCoV patients, we...

10.1101/2020.02.08.939892 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-02-18

This study was conducted to evaluate the effects of grape seed extract (GSE) on growth performance, immunity, antioxidant capacity, relative organ weight, jejunum morphology, ileal microflora, and meat quality in Pekin ducks. A total 1,500 female 1-day-old ducklings (52.0 ± 0.2 g) were blocked based body weight (BW) randomly allocated into 3 treatments with 10 replicates 50 birds each. The experiment lasted for 6 wk, dietary included corn-soybean meal-based diet supplemented 0, 0.01, 0.02%...

10.1016/j.psj.2019.12.014 article EN cc-by-nc-nd Poultry Science 2020-02-25

Zearalenone (ZEA) is a resorcylic acid lactone derivative derived from various Fusarium species that are widely found in food and feeds. The molecular structure of ZEA resembles the mammalian hormone 17β-oestradiol, thus zearalenone its metabolites known to compete with endogenous hormones for estrogen receptors binding sites activate transcription oestrogen-responsive genes. However, effect long-term low-dose exposure on reproductive response Bacillus subtilis ANSB01G culture first-parity...

10.1186/s40104-022-00686-3 article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2022-04-06

Cardiovascular and renal inflammation induced by Aldosterone (Aldo) plays an important role in the pathogenesis of hypertension fibrosis. Toll-like receptor 4 (TLR4) signaling contributes to inflammatory cardiovascular diseases, but its Aldo-induced damage is not clear. In current study, rats were treated with Aldo-salt combined TAK-242 (a TLR4 antagonist) for weeks. Hemodynamic, cardiac parameters assayed at indicated time. We found that Aldo-salt-treated present hypertrophy dysfunction....

10.1371/journal.pone.0142456 article EN cc-by PLoS ONE 2015-11-10

Rapidly progressive glomerulonephritis caused by antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is typically characterized as pauci-immune glomerulonephritis. However, immune complex (IC) deposition in the glomerulus has been reported a growing number of studies. Here, we assess presence glomerular deposits alongside renal outcome myeloperoxidase (MPO)-ANCA associated (MPO-ANCA GN). Clinical and histopathologic characteristics 97 patients with MPO-ANCA GN classified...

10.3389/fimmu.2021.625672 article EN cc-by Frontiers in Immunology 2021-03-25

This study was conducted to determine the effects of maize naturally contaminated with aflatoxin B1 (AFB1) on growth performance, intestinal morphology, relative digestive organs weight, enzymes activities, and biochemical index development in ducks. A total 640 ducks blocked basis sex body then allocated randomly 2 treatments 20 pens per treatment 16 pen. The experiment lasted for 5 wk, dietary included basal diet (CON) diets 100% normal replaced by AFB1 maize. Detectable levels other...

10.3382/ps/pew420 article EN cc-by-nc-nd Poultry Science 2016-12-06

This study was conducted to determine the effect of astaxanthin (AX) produced by Phaffia rhodozyma (PR) on growth performance, antioxidant activities, relative organ weight, and meat quality in Pekin ducks. A total 1,440 female one-day-old ducklings (52.3 ± 0.4 g) were blocked based body weight (BW), randomly allotted 3 treatments with 8 replicates 60 birds each. The experiment lasted for 6 wk, dietary included corn–soybean meal-based diet supplemented 0, 0.15, 0.3% PR. supplementation AX...

10.3382/ps/pez256 article EN cc-by-nc-nd Poultry Science 2019-06-01

Water security is under threat worldwide from climate change. A warming would accelerate evaporation and cryosphere melting, leading to reduced water availability unpredictable supply. However, the crisis in Northern Slope of Tianshan Mountains (NSTM) faces dual challenges because demands for fast-growing urban areas have put heavy pressure on resources. The mountain-oasis-desert system features glacier-fed rivers that sustain intensive use oasis end desert as fragile terminal lakes. complex...

10.1016/j.geosus.2022.08.004 article EN cc-by Geography and sustainability 2022-09-01

The H5N1 subtype highly pathogenic avian influenza virus (HPAIV) reveals high variability and threatens poultry production public health. To prevent the spread of HPAIV, we developed an virus-like particle (VLP) vaccine based on insect cell-baculovirus expression system. Single immunization VLP vaccines induced levels HI antibody titres provided effective protection against homologous challenge comparable to commercial inactivated vaccine. Meanwhile, assessed relative efficacy different...

10.1080/22221751.2023.2287682 article EN cc-by Emerging Microbes & Infections 2023-11-23

The exacerbation of IgA nephropathy (IgAN) is related to respiratory tract infection with hemolytic streptococcus (HS), but the mechanism unknown. In this study we investigated role chemokine ligand 20 (CCL20) in response effect T helper 17 (Th17) cells pathogenesis IgAN associated HS.Thirty mice were randomly divided into five groups: control (control), (IgAN), HS-infected (HS-IgAN), CCL20-treated (CCL20-IgAN), and HS infected (CCL20-HS-IgAN). induced lipopolysaccharide, carbon...

10.1371/journal.pone.0108723 article EN cc-by PLoS ONE 2014-09-29

This study was conducted to evaluate the effects of Achyranthes bidentata polysaccharide (ABP) on growth performance, antioxidant capacity, immune function, relative organ weight, ileal microflora, and meat quality in Pekin ducks. A total 1,200 female 1-day-old ducklings (51.2 ± 0.2 g) were blocked based body weight (BW) randomly allocated into 3 treatments with 10 replicates 40 birds each. The experiment lasted for 6 wk, dietary included corn–soybean meal–based diet supplemented 0, 0.02,...

10.1016/j.psj.2020.06.026 article EN cc-by-nc-nd Poultry Science 2020-07-01

This study was conducted to evaluate the alleviation of Bacillus subtilis ANSB01G culture as zearalenone (ZEA) biodegradation agent on oxidative stress, cell apoptosis and fecal ZEA residue in first parity gestation sows during gestation. A total 80 first-parity gilts (Yorkshire × Landrace) were randomly allocated 4 dietary treatments with 20 replications per treatment one gilt replicate. The follows: CO (positive control); MO (negative control, level at 246 μg/kg diet); COA (CO + B. 2 109...

10.1016/j.aninu.2020.03.011 article EN cc-by-nc-nd Animal nutrition 2020-07-07

Two experiments with growing pigs were conducted to investigate the effects of two distinct multienzyme preparations on nutrient digestibility, growth performance and blood profiles.In Exp. 1, a total 96 (29.7±0.69 kg) utilized in 42-day digestibility trial using four dietary treatments: CON (control diet), ENDO (control+0.10%Endopower), NSPase1 (control+0.10%NSPase) NSPase2 (control+0.20%NSPase).Endopower was commercial preparation which contained α-galactosidase, galactomannase, xylanase...

10.5713/ajas.2010.10123 article EN cc-by Asian-Australasian Journal of Animal Sciences 2010-10-25

This study was conducted to evaluate the effects of dietary supplementation with chito-oligosccharide (COS) on egg production, nutrient digestibility, quality and blood profiles in laying hens.A total 240 Hy-line Brown hens were randomly allocated into one following 5 treatments: i) CON, basal diet; ii) ANT, diet+44 mg/kg avilamycin; iii) COS0.2, diet+200 COS; iv) COS0.4,basal diet+400 v) ANTCOS, COS+22 avilamycin.The experiment lasted for 6 wk.No change weight (p>0.05) observed during trial...

10.5713/ajas.2010.10025 article EN cc-by Asian-Australasian Journal of Animal Sciences 2010-10-25
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