- Influenza Virus Research Studies
- Viral gastroenteritis research and epidemiology
- Animal Disease Management and Epidemiology
- Escherichia coli research studies
- Antibiotic Resistance in Bacteria
- Respiratory viral infections research
- Sperm and Testicular Function
- Salmonella and Campylobacter epidemiology
- Pharmaceutical and Antibiotic Environmental Impacts
- interferon and immune responses
- Enterobacteriaceae and Cronobacter Research
- Viral Infections and Vectors
- Aquaculture disease management and microbiota
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive Health and Technologies
- Hepatitis Viruses Studies and Epidemiology
- Molecular Biology Techniques and Applications
- Glutathione Transferases and Polymorphisms
- Viral Infectious Diseases and Gene Expression in Insects
- Silkworms and Sericulture Research
- Probiotics and Fermented Foods
- Hormonal and reproductive studies
- Bacteriophages and microbial interactions
- Biosensors and Analytical Detection
- Recycling and Waste Management Techniques
Chinese Academy of Fishery Sciences
2025
Hangzhou Normal University
2018
Hangzhou Center for Disease Control and Prevention
2007-2016
Zhejiang Center for Disease Control and Prevention
2015-2016
Iowa State University
2016
Centers for Disease Control and Prevention
2009-2015
Dali University
2011-2014
Avian influenza virus A of the novel H7N9 reassortant subtype was recently found to cause severe human respiratory infections in China. Live poultry markets were suspected locations infection sources, based on cases' exposure histories and sequence similarities between viral isolates. To explore role live origin virus, we systematically examined environmental specimens from local farms Hangzhou, using real-time reverse transcription-PCR (RT-PCR) as well high-throughput next-generation...
A novel H7N9 influenza virus has been discovered as the causative identity of emerging acute respiratory infection cases in Shanghai, China. This also identified neighboring area Hangzhou City Zhejiang Province. In this study, epidemiologic, clinical, and virological data from three patients who were confirmed to be infected by collected analyzed. Human specimens chicken feces a contacted free market tested for real-time reverse transcription PCR (RT-PCR) sequencing. The clinical features...
The aim of this study was to characterize fluoroquinolone-resistant Shigella and determine whether the qnr aac(6')-Ib-cr genes could contribute sporadic shigellosis at clinic in Hangzhou area China.A total 202 strains (79 sonnei 123 flexneri ) isolated from cases 1998 2007 were analysed for their antimicrobial susceptibility. gyrA, gyrB, parC, parE, profiles incompatibility plasmids characterized. Chromosomal DNA fingerprinting determined by XbaI-based digestion PFGE.All S. susceptible...
Effluents from hospital and aquaculture are considered important sources of quinolone resistance. However, little information is available on the impact this effluent nearby rivers. In study, 188 ciprofloxacin-resistant bacterial isolates obtained rivers near hospitals were screened for plasmid-mediated resistance (PMQR) genes. Species identification, antibiotic susceptibility testing, PMQR gene transferability assessment conducted PMQR-positive bacteria. Representative qnrS2-encoding...
Toxin-antitoxin (TA) systems are widely distributed in bacteria and play an important role maintaining plasmid stability. The leading foodborne pathogen, Campylobacter jejuni, can carry multiple plasmids associated with antibiotic resistance or virulence. Previously a virulence named pVir was identified C. jejuni 81-176 IA3902, but determining the of pathogenesis has been hampered because cannot be cured. In this study, we report identification two TA that located on respectively. virA...
Abstract Background We examined the clinical and epidemiological characteristics of 30 cases human infection with avian influenza A(H7N9) virus in Hangzhou investigated their external environments to provide evidence for contact tracing disease prevention control. Methods The confirmed from April 1 through May 1, 2013 were studied. Field epidemiologic surveys conducted collect data. Case-related environmental specimens collected etiologic detection. Results Thirty 2013, including one...
KIT/KITLG signaling system is crucial for spermatogenesis, which suggests that KIT and KITLG genes may be involved in spermatogenesis impairment male infertility. To explore the possible association of with infertility having impairment, polymorphism distributions SNP rs3819392 gene as well rs995030 rs4474514 were investigated 372 patients idiopathic azoospermia or oligospermia 205 fertile controls. As a result, significant differences observed between The frequencies allele G (94.2% versus...
The complete sequences of two previously reported plasmids carrying plasmid-mediated quinolone resistance genes from Shigella flexneri in China have not been available. present study using the p5-C3 assembly method revealed that (1) plasmid pSF07201 with aac(6')-Ib-cr had 75,335 bp antibiotic CTX-M-3, TEM-1, and FosA3; (2) seven fragments more than 99% homology corresponding plasmids; (3) other pSF07202 qnrS 47,669 gene TEM-1 99.95% a segment pKF362122, which has location 162,490 to 163,146....
To investigate and report on the clinical epidemiological characteristics of first case human infection with avian influenza A(H7N9) virus in Hangzhou, China. A field survey was used to study Hangzhou. The patient a 39-year-old male chef history exposure farm product market poultry prior onset disease 15 March 2013. He had diarrhea, chills, pyrexia, intermittent cough freshly red foamy bloody sputum early his disease. His fever > 39 °C continued for week rapid progression. Computed...