A5034552993- Invertebrate Immune Response Mechanisms
- Crustacean biology and ecology
- Genomics and Phylogenetic Studies
- Environmental DNA in Biodiversity Studies
- Insect symbiosis and bacterial influences
- Neurobiology and Insect Physiology Research
- Insects and Parasite Interactions
- Parasite Biology and Host Interactions
- Genetic diversity and population structure
- Invertebrate Taxonomy and Ecology
- Chromosomal and Genetic Variations
- Tardigrade Biology and Ecology
- Aquaculture disease management and microbiota
- Cell Image Analysis Techniques
- Bioinformatics and Genomic Networks
- Gene expression and cancer classification
- Protist diversity and phylogeny
- Aquaculture Nutrition and Growth
- Aquatic Invertebrate Ecology and Behavior
- Fish Ecology and Management Studies
- Molecular Biology Techniques and Applications
- Coral and Marine Ecosystems Studies
- Plant Disease Resistance and Genetics
- Cancer Diagnosis and Treatment
- Antimicrobial Peptides and Activities
Justus-Liebig-Universität Gießen
2024
Centre National de la Recherche Scientifique
2022-2024
LOEWE Centre for Translational Biodiversity Genomics
2021-2024
Senckenberg Biodiversity and Climate Research Centre
2021-2024
Université de Strasbourg
2022-2024
University of Koblenz and Landau
2023-2024
Institute for Environmental Sciences
2023
Senckenberg Society for Nature Research
2022
University of Zagreb
2020-2021
Progress in genome sequencing now enables the large-scale generation of reference genomes. Various international initiatives aim to generate genomes representing global biodiversity. These provide unique insights into genomic diversity and architecture, thereby enabling comprehensive analyses population functional genomics, are expected revolutionize conservation genomics.
Austropotamobius torrentium is a freshwater crayfish species native to central and south-eastern Europe, with an intricate evolutionary history the highest genetic diversity recorded in northern-central Dinarides (NCD). Its populations are facing declines, both number size across its entire range. By extanding current knowledge on of this species, we aim assist conservation programmes. Multigene phylogenetic analyses were performed using different divergence time estimates based...
Abstract Background The advancement of sequencing technologies results in the rapid release hundreds new genome assemblies a year providing unprecedented resources for study evolution. Within this context, significance in-depth analyses repetitive elements, transposable elements (TEs) particular, is increasingly recognized understanding Despite plethora available bioinformatic tools identifying and annotating TEs, phylogenetic distance target species from curated classified database element...
For over a century, scientists have studied host-pathogen interactions between the crayfish plague disease agent Aphanomyces astaci and freshwater crayfish. It has been hypothesised that North American hosts are disease-resistant due to long-lasting coevolution with pathogen. Similarly, increasing number of latent infections reported in historically sensitive European seems indicate similar coevolutionary processes occurring A. astaci. Our current understanding these is largely focused on...
Abstract Soil invertebrates are among the least understood metazoans on Earth. Thus far, lack of taxonomically broad and dense genomic resources has made it hard to thoroughly investigate their evolution ecology. With MetaInvert we provide draft genome assemblies for 232 soil invertebrate species, representing 14 common groups 94 families. We show that this data substantially extends taxonomic scope DNA- or RNA-based identification. Moreover, confirm theories cannot be generalised across...
Pontastacus leptodactylus is a native European crayfish species found in both freshwater and brackish environments. It has commercial importance for fisheries aquaculture industries. Up till now, most studies concerning P. have focused onto gaining knowledge about its phylogeny population genetics. However, little known the chromosomal evolution genome organization of this species. Therefore, we performed clustering analysis low coverage genomic dataset to identify characterize repetitive...
Abstract Background Biodiversity in freshwater ecosystems is declining due to an increased anthropogenic footprint. Freshwater crayfish are keystone species and play a crucial role shaping the structure function of their habitats. The Idle Crayfish Austropotamobius bihariensis native European with narrow distribution range, endemic Apuseni Mountains (Romania). Although its area small, populations anthropogenically fragmented. In this context, assessment conservation status timely. Results...
Invasive alien crayfish threaten the diversity of freshwater ecosystems and native fauna. In Europe, this is largely due to transmission plague susceptible crayfish. Many invasive species tolerate plague, but infection still has potential reduce fitness a tolerant host energy trade-offs between immune response maintenance life-history traits, such as growth reproduction. combination with other unfavourable conditions, could alter further invasion success an otherwise successful invader. We...
Abstract Soil invertebrates are among the least understood metazoans on Earth. Thus far, lack of taxonomically broad and dense genomic resources has made it hard to thoroughly investigate their evolution ecology. With MetaInvert we provide draft genome assemblies for 232 soil invertebrate species, representing 14 common groups 94 families. We show that this data substantially extends taxonomic scope DNA- or RNA-based identification. Moreover, demonstrate theories cannot be generalised across...
Repetitive elements are a major component of DNA sequences due to their ability propagate through the genome. Characterization Metazoan repetitive profiles is improving; however, current pipelines fail identify significant proportion divergent repeats in non-model organisms. The Decapoda order, for which repeat content analyses largely lacking, characterized by extremely variable genome sizes that suggest an important presence elements. Here, we developed new standardized pipeline annotate...
Crayfish plague disease, caused by the oomycete pathogen Aphanomyces astaci represents one of greatest risks for biodiversity freshwater crayfish. This data article covers de novo transcriptome assembly and annotation noble crayfish marbled challenged with Ap. astaci. Following controlled infection experiment (Francesconi et al. in Front Ecol Evol, 2021, https://doi.org/10.3389/fevo.2021.647037 ), we conducted a differential gene expression analysis described (Boštjančić BMC Genom, 2022,...
Repetitive elements are a major component of DNA sequences due to their ability propagate through the genome. Characterization Metazoan repetitive profiles is picking up, however, current pipelines failing identify significant proportion divergent repeats in non-model organisms. The order Decapoda, for which repeat content analyses largely lacking, characterized by extremely variable genome sizes that suggest an important presence elements. Here we developed new standardized pipeline...
Transcriptional silencing of 35S rDNA loci inherited from one parental species is occurring relatively frequently in allopolyploids. However, molecular mechanisms by which it selected for transcriptional remain unclear. We applied NGS, silver staining and bisulfite sequencing to study the structure, expression methylation landscape two allopolyploids common origin, allotetraploid Anemone multifida (2n = 4x 32, genome composition BBDD) allohexaploid A. baldensis 6x 48, AABBDD), their donors,...
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Introduced into Europe from North America 150 years ago alongside its native crayfish hosts, the invasive pathogen Aphanomyces astaci is considered one of main causes European population decline. For past two centuries, this oomycete has been extensively studied, with more recent efforts focused on containing and monitoring spread across continent. However, after introduction new strains, newly-discovered diversity A. in several coevolution host, a assessment traits linked to pathogen's...
Transcription factors (TFs) have an important role in the regulation of gene expression network. The TFs immune response freshwater crayfish is poorly understood, but leveraging regulatory mechanisms could augment resistance against invasive oomycete pathogen, Aphanomyces astaci. Previous studies indicated that CCAAT/enhancer-binding protein (C/EBP) and putative Krüppel homolog-1 (Kr-h1) might play a stress noble (Astacus astacus). Here, we aimed to further characterise these two products...
Abstract Introduction of invasive North American crayfish species and their pathogen Aphanomyces astaci has significantly contributed to the decline European freshwater populations. In this study, noble crayfish, a susceptible native species, marbled an disease-resistant were challenged with haplogroup A (low virulence) B (high strain A. . Hepatopancreatic tissue was isolated 3 21 days post-challenge. Our results revealed strong up-regulation in expression levels prophenoloxidase cascade...
Abstract The advancement of sequencing technologies results in the rapid release hundreds new genome assemblies a year providing unprecedented resources for study evolution. Within this context, significance in-depth analyses repetitive elements, transposable elements (TEs) particular, is increasingly recognized understanding Despite plethora available bioinformatic tools identifying and annotating TEs, phylogenetic distance target species from curated classified database element sequences...