Biraj Man Karmacharya

ORCID: 0000-0001-8983-0235
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Research Areas
  • Global Public Health Policies and Epidemiology
  • Chronic Disease Management Strategies
  • Diabetes Management and Education
  • Healthcare Systems and Reforms
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Global Maternal and Child Health
  • Cardiovascular Health and Risk Factors
  • Obesity, Physical Activity, Diet
  • Obesity and Health Practices
  • Cerebral Palsy and Movement Disorders
  • COVID-19 epidemiological studies
  • Diabetes Management and Research
  • Vaccine Coverage and Hesitancy
  • COVID-19 and Mental Health
  • Global Health Care Issues
  • Long-Term Effects of COVID-19
  • SARS-CoV-2 and COVID-19 Research
  • Global Health and Epidemiology
  • Antimicrobial Resistance in Staphylococcus
  • Emergency and Acute Care Studies
  • Entomological Studies and Ecology
  • Interprofessional Education and Collaboration
  • Body Composition Measurement Techniques
  • Blood Pressure and Hypertension Studies
  • Antibiotic Use and Resistance

Kathmandu University
2016-2025

Dhulikhel Hospital
2016-2025

Norwegian University of Science and Technology
2018-2024

University of Bergen
2023

Institute for Social and Environmental Research-Nepal
2022

Sun Yat-sen University
2017-2020

University of Washington
2017-2020

University of Massachusetts Boston
2020

New Generation University College
2020

Seoul National University
2020

Introduction Geographical accessibility is important against health equity, particularly for less developed countries as Nepal. It to identify the disparities in geographical three levels of public facilities across Nepal, which has not been available. Methods Based on up-to-date dataset Nepal formal 2021, we measured by calculating travel time nearest facility (ie, primary, secondary and tertiary) at 1×1 km 2 resolution under two modes: walking motorised. Gini Theil L index were used assess...

10.1136/bmjgh-2021-006786 article EN cc-by-nc BMJ Global Health 2021-10-01

In South Asia, data on enteric fever are sparse outside of urban areas. We characterized diagnosis patterns and the burden culture-confirmed cases in peri-urban rural Nepal.We used national reports to estimate rates over 20 years (1994-2014) conducted a prospective study patients presenting with >72-hour history 4 healthcare facilities (during August 2013-June 2016). compared clinical characteristics Salmonella Typhi or Paratyphi infection those without fever. generalized additive models...

10.1093/infdis/jix221 article EN cc-by The Journal of Infectious Diseases 2017-05-10

Background Inappropriate use of antimicrobials is a global public health issue, particularly in developing countries, including Nepal, where over-the-counter sales and self-medication are common. Objectives To explore knowledge, perceptions, practices their resistance among medicine dispensers community members Nepal. Methods The study was conducted three rural five urban municipalities the Kavrepalanchok district from May 2021 to August 2021. Data were collected using two qualitative...

10.1371/journal.pone.0297282 article EN cc-by PLoS ONE 2024-01-19

Abstract Background Type 2 diabetes mellitus (T2DM) has increased globally; with a disproportionate burden in South and Southeast Asian countries, including Nepal. There is an urgent need for clinically cost-effective culturally adapted T2DM management programs. In this study, we aim to assess the effectiveness of community based appropriate lifestyle intervention improving care people T2DM. Methods We will conduct cluster randomized control trial evaluate outcomes. The be conducted 30...

10.1186/s13063-023-07451-5 article EN cc-by Trials 2023-07-04

For the past three decades, burden of diabetes in Nepal has been steadily increasing, with an estimated 3% annual increase since year 2000. Although is methods addressing challenge have remained largely unchanged. This study sought to assess current state services provided by health facilities and identify major barriers that people commonly face Nepal. this qualitative study, we selected five varying levels locations. At each site, employed unique methods: a process evaluation treatment...

10.1093/heapol/czy011 article EN Health Policy and Planning 2018-01-22

Cardiovascular diseases (CVDs) are the leading cause of disease burden globally, disproportionately affecting low and middle-income countries. The continued scarcity literature on CVDs in Nepal has thwarted efforts to develop population-specific prevention management strategies. This article reports including, prevalence, incidence, disability basis as well trends over past two decades by age gender. We used Institute Health Metrics Evaluation's Global Burden Diseases database cardiovascular...

10.1016/j.ijcha.2020.100602 article EN cc-by-nc-nd IJC Heart & Vasculature 2020-07-31

Limited sensitivity and specificity of current diagnostics lead to the erroneous prescription antibiotics. Host-response-based could address these challenges. However, using 4,200 samples across 69 blood transcriptome datasets from 20 countries patients with bacterial or viral infections representing a broad spectrum biological, clinical, technical heterogeneity, we show host-response-based gene signatures have lower accuracy distinguish intracellular than extracellular infections. Using...

10.1016/j.xcrm.2022.100842 article EN cc-by Cell Reports Medicine 2022-12-01

As diabetes increases globally, high mortality due to complications of uncontrolled sugar. Medication adherence is important control blood sugar and prevent its complications. Objective the study was identify factors associated with medication among type 2 patients. A cross-sectional conducted 343 patients visiting Dhulikhel Hospital, Nepal, for their fasting test from September December 2016. Inclusion criteria: diabetes, under past three months (minimum), age ≥ 18 years. The outcome...

10.3390/ijerph20021537 article EN International Journal of Environmental Research and Public Health 2023-01-14

Objective To assess the prevalence and factors associated with cyberbullying cyber-victimisation among high school adolescents of Pokhara Metropolitan City, Nepal. Design A cross-sectional study. Setting Participants We used convenient sampling to enrol 450 aged 16–19 years from four distinct higher secondary schools in City. Outcome measures administered Cyberbullying an Online Aggression Survey determine cyber-victimisation. Univariate multivariate logistic regression analyses were...

10.1136/bmjopen-2023-081016 article EN cc-by-nc BMJ Open 2024-03-01

Background Gallbladder cancer (GBC) is a rare, highly fatal disease with diagnosis in advanced stage and low survival rate. Nepal ranked 4 th position highest rates of GBC for 10 countries 2020. Objective To find the association between socio-demographic, behavioral environmental factors associated development GBC. Method A case-control study was conducted 2021/22 newly diagnosed gallbladder cases from three cancer-specialized hospitals one tertiary (superspeciality) hospital. Controls were...

10.1371/journal.pone.0317249 article EN cc-by PLoS ONE 2025-01-22

Background The COVID-19 pandemic has widened inequities, affecting migrant and refugee populations in vulnerable situations, who may face elevated risks of infection, constrained healthcare access discrimination. Inclusive vaccination campaigns are recommended, but barriers persist. This study aimed to identify facilitators estimate coverage among refugees migrants low- middle-income countries, emphasising inclusive policies for effective rollout. Methods A mixed-method was conducted two...

10.1136/bmjopen-2024-087629 article EN cc-by-nc-nd BMJ Open 2025-01-01

Globally, the burden of cardiovascular disease is on rise. Despite WHO's and UN's frantic efforts, it appears less probable that 25 by aim will be met. Early identification at-risk cases using a risk scoring system can aid in achieving these goals; however, for primary secondary prevention, suitability systems countries with medium to low resources, including Asians, respect accuracies, challenge as majority them are developed from non-Asian cohorts. In light methodological considerations,...

10.1101/2025.02.07.25321756 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2025-02-08

e13858 Background: The global cancer burden disproportionately impacts low- and middle-income countries. In Nepal, breast cervical are the two leading causes of deaths in women. Yet, there is no national screening program, less than 10% eligible women have undergone screening. This qualitative study aims to identify facilitators barriers at individual, community, health system levels. Methods: We conducted 60-90 minute face-to-face in-depth interviews (IDI) (n = 28) with community 30-60...

10.1200/jco.2025.43.16_suppl.e13858 article EN Journal of Clinical Oncology 2025-05-28

Objective To explore the perceptions, enablers and barriers to employees’ healthy eating in a hospital site. Design A qualitative study including focus group discussion in-depth interview, data were analysed using thematic analysis method. Setting The was carried out among employees of Dhulikhel Hospital-Kathmandu University Hospital, located about 30 km east Nepal's capital Kathmandu. Participants Focus discussions conducted 33 participants, who divided into four groups: (a) support staff...

10.1136/bmjopen-2019-031404 article EN cc-by-nc BMJ Open 2020-02-01

Nepal moved from a unitary government to federal system of in 2015 under its constitution. is democratic republic governed by three levels government: federal, provincial, and local level. The response COVID-19 has been majorly led controlled the government. All are performing their responsibilities; however, they face various challenges responding COVID-19. This study aimed critically analyze Nepal's health context response.We conducted semi-structured in-depth interviews telephone among...

10.1016/j.dialog.2023.100142 article EN cc-by Dialogues in Health 2023-06-10

Introduction . We have previously determined the prevalence of human papillomavirus (HPV) infection among women in rural Nepal. In current study, we also wanted to examine and risk factors for other sexually transmitted infections (STIs) same population. Methods Population-based study nonpregnant ≥ 15 years who were married or had a history marriage past, residing five villages Data on sociodemographic characteristics, reproductive history, genitourinary symptoms collected, gynecological...

10.1155/2018/4980396 article EN cc-by Infectious Diseases in Obstetrics and Gynecology 2018-08-26

Health sector priorities and interventions to prevent manage noncommunicable diseases injuries (NCDIs) in low- lower-middle-income countries (LLMICs) have primarily adopted elements of the World Organization Global Action Plan for NCDs 2013-2020. However, there been limited efforts LLMICs prioritize among conditions health-sector NCDIs based on local epidemiology contextually relevant risk factors or that incorporate equitable distribution health outcomes. The Lancet Commission Reframing...

10.9745/ghsp-d-21-00035 article EN cc-by Global Health Science and Practice 2021-08-03

Abstract Background Physiotherapy is a growing profession in Nepal. Despite efforts to promote strengthening and development, there are still challenges providing equitable access availability services, particularly underserved areas. Updated information needed address provide proper planning for resource allocation. Objective To assess implementation of physiotherapy services explore plans, policies the general status Method Implementation was assessed with cross-sectional survey conducted...

10.1186/s12913-024-10747-0 article EN cc-by BMC Health Services Research 2024-03-06

In this study we aimed to determine the overall and type-specific prevalence of cervical human papillomavirus (HPV) infection risk factors for such among women in rural Nepal, investigate distribution HPV by cytology.The was conducted aged ≥15 years five villages within Kavre District Nepal. Sociodemographic data information on cancer were obtained through an interview, a specimen collected DNA detection typing using Anyplex™ ll HPV28 Detection system, Papanicolaou test.Among 1289 whom valid...

10.1111/aogs.13036 article EN Acta Obstetricia Et Gynecologica Scandinavica 2016-10-13

Seasonal Hyperacute Panuveitis (SHAPU) is an eye disease of unclear aetiology occurring cyclically during the autumn in odd years Nepal causing blindness within a week. This study first its type to investigate risk factors SHAPU.A multicentric national level case-control was performed 2017 SHAPU outbreak. Cases were matched controls 1:3 ratio based on age, sex and geographic area.Questionnaire-based personal interview used categorized as biological behavioral. For univariate analysis,...

10.1080/09286586.2020.1820533 article EN Ophthalmic Epidemiology 2020-09-27

Background Nepal, in recent years, is witnessing an increasing problem of type 2 diabetes that has resulted significant premature deaths and disability. Prevention management non-communicable diseases (NCDs) including have been prioritized the national policies guidelines Nepal Government. However, research looking at overview implementation existing for prevention control scarce. Hence, this study reviewed related its process primary health care level Nepal. Methods This involved two...

10.3389/fpubh.2022.763784 article EN cc-by Frontiers in Public Health 2022-02-09

Background Stakeholder engagement is important from the management point of view to capture knowledge, increase ownership, reduce conflict, encourage partnership, as well develop an ethical perspective that facilitates inclusive decision making and promotes equity. However, there dearth literature in process stakeholder engagement. The purpose this paper describe increasing highlight lessons learnt on while designing, implementing, monitoring a study diabetes hypertension prevention...

10.1371/journal.pone.0276478 article EN cc-by PLoS ONE 2022-10-20
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