A5003589720- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Pulmonary Hypertension Research and Treatments
- Respiratory Support and Mechanisms
- Travel-related health issues
- Respiratory and Cough-Related Research
- High Altitude and Hypoxia
- Protease and Inhibitor Mechanisms
- COVID-19 Clinical Research Studies
- Neonatal Respiratory Health Research
- Allergic Rhinitis and Sensitization
- Stress and Burnout Research
- Pediatric health and respiratory diseases
- Peptidase Inhibition and Analysis
- Dermatological diseases and infestations
- Pleural and Pulmonary Diseases
- Health and Lifestyle Studies
- Cystic Fibrosis Research Advances
- Long-Term Effects of COVID-19
Fundación Neumológica Colombiana
2019-2024
Universidad de La Sabana
2022-2023
Approximately 20% of people in Latin American live above 2500 meters sea level. In this ethnically and socioeconomically diverse population, it is challenging to differentiate the effects altitude from population differences lung function. Aim To quantify contribution on variability function measured by spirometry America. Methods Data healthy individuals living nine cities across American, (from level >2500 level) were collated. Z-scores for FEV 1 , FVC, /FVC calculated using available...
Pulmonary hypertension (PH) is associated with poor prognosis for patients chronic obstructive pulmonary disease (COPD). Most of the knowledge about PH in COPD has been generated at sea level, limited information high altitude (HA). To assess prevalence and severity living a HA city (2,640 m). Cross-sectional study forced expiratory volume first second / vital capacity ratio (FEV1/FVC) post-bronchodilator <0,7. Transthoracic echocardiography (TTE), spirometry, carbon monoxide diffusing...
Impulse oscillometry (IOS) is used to measure airway impedance. It an effective tool for diagnosing and treating respiratory diseases, it has the advantage that does not require forced maneuvers. IOS reference values are required each population group.This study aimed determine bronchodilator response in healthy preschool children living Bogotá, Colombia.We performed a cross-sectional who had no history of disease; 96 fit parameters testing normal according American Thoracic Society European...
Laura Gochicoa-Rangel, Santiago C. Arce, Carlos Aguirre-Franco, Wilmer Madrid-Mejía, Mónica Gutiérrez-Clavería, Lorena Noriega-Aguirre, Patricia Schonffeldt-Guerrero, Agustín Acuña-Izcaray, Arturo Cortés-Telles, Luisa Martínez-Valdeavellano, Federico Isaac Hernández-Rocha, Omar Ceballos-Zúñiga, Rodrigo Del Rio Hidalgo, Sonia Sánchez, Erika Meneses-Tamayo, and Iván Chérrez-Ojeda; on Behalf of the Respiratory Physiology Project in COVID-19 (FIRCOV). Effect altitude respiratory functional...
Background There is a lack of information on house dust mite (HDM) sensitization and phenotype distribution in patients with severe asthma (SA) living permanently at high-altitude (HA) tropical regions, which may be different.
Pulmonary hypertension (PH) is associated with decreased exercise tolerance in chronic obstructive pulmonary disease (COPD) patients, but the altitude response to those patients unknown. Our objective was compare capacity, gas exchange and ventilatory alterations between COPD PH (COPD-PH) without (COPD-nonPH) residents at high (2640 m).One hundred thirty-two COPD-nonPH, 82 COPD-PH, 47 controls were included. Dyspnea by Borg scale, oxygen consumption (VO2), work rate (WR), equivalents...
Objective: The goal of this study was to compare the microbiology severe exacerbations chronic obstructive pulmonary disease (COPD) requiring admission intensive care unit (ICU), in patients with pneumonia compared those that did not have. Methods: We conducted a retrospective cross-sectional included COPD exacerbation. took microbiologic and serologic samples etiology exacerbation chest X-ray see whether or it had associated pneumonia. Results: Ninety-one were study. 53/91 (58%) most...
Abstract Background Alpha-1 antitrypsin deficiency (AATD) is an underrecognized genetic disorder associated mainly with pulmonary emphysema and Chronic Obstructive Pulmonary Disease (COPD). All individuals COPD regardless of age or ethnicity should be tested for AATD, but in Colombia its prevalence unknown. Main objective To determine the mutations, present AATD adult patients Colombia, using a genotyping test on cells from oral mucosa. Methods This was multicentre, observational,...
Introducción: La enfermedad pulmonar obstructiva crónica (EPOC) constituye un importante desafío tanto en el ámbito económico como de la salud pública, a nivel mundial contexto colombiano. Esta condición no solo repercute los pacientes que padecen, sino también afecta sus cuidadores y al sistema su conjunto. Se ha observado incremento ausentismo laboral por parte familiares, lo resulta pérdidas económicas oportunidades laborales, agravando aún más impacto adverso individuo entorno familiar....
Introducción: es fundamental garantizar que los instrumentos de medición al ser usados en contextos distintos a fueron desarrollados se ajusten su lenguaje y compresibilidad; el cuestionario principal usado estudio PLATINO, cual estableció la prevalencia enfermedad pulmonar obstructiva crónica áreas metropolitanas Latinoamérica por Asociación Latinoamericana del Tórax, sin incluir población colombiana. Objetivo: realizar validación facial, confiabilidad comprensibilidad PLATINO para...
The Latin American population is widely diverse in race and ethnicity; many individuals identified as mixed ethnicity makes selection of spirometry reference equations difficult. Additionally, 17% Americans live above 2500 meters sea level which may influence lung development during childhood. Our aim was to investigate the role altitude on spirometry, whether a race-neutral equation (GLI-Global) fits subjects living at different altitudes. <b>Methods:</b> Data from 9 cities, classified low...
<b>Background:</b> Preserved ratio impaired spirometry (PRISm) is defined as a FEV<sub>1</sub> of less than 80% predicted and FEV<sub>1</sub>/forced vital capacity (FVC) 0·70 or higher. Previous research has indicated that PRISm associated with respiratory symptoms precursor chronic obstructive pulmonary disease (COPD). However, these findings are based on relatively small selective cohorts short follow-up. We aimed to determine the prevalence, risk...