A5031515123- Chronic Obstructive Pulmonary Disease (COPD) Research
- High Altitude and Hypoxia
- Asthma and respiratory diseases
- Air Quality and Health Impacts
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Pulmonary Hypertension Research and Treatments
- Respiratory Support and Mechanisms
- Respiratory viral infections research
- Cardiovascular and exercise physiology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Occupational and environmental lung diseases
- Cardiovascular and Diving-Related Complications
- Occupational exposure and asthma
- Energy and Environment Impacts
- Climate Change and Health Impacts
- Health and Lifestyle Studies
- Neonatal Respiratory Health Research
- Occupational Health and Safety Research
- Pneumonia and Respiratory Infections
- Biosimilars and Bioanalytical Methods
- Cytomegalovirus and herpesvirus research
- Inhalation and Respiratory Drug Delivery
- HER2/EGFR in Cancer Research
- Monoclonal and Polyclonal Antibodies Research
Fundación Neumológica Colombiana
2016-2025
Universidad de La Sabana
2012-2025
Universidad El Bosque
2022-2024
Hospital Universitario San Ignacio
2024
Universidad Nacional de Córdoba
2019
Universidad de Oviedo
2016
Hospital Universitario Araba
2015
University of the Basque Country
2015
Universidad de Los Andes
2013
Instituto Cajal
1999
There are differences in the prevalence and risk factors of asthma around world. The epidemiological situation adults 40 years older is not well established. Our aim was to determine prevalence, underdiagnosis wheezing Colombia.A cross-sectional, population-based study including 5539 subjects from 93 selected by a probabilistic sampling technique five cities conducted.respiratory symptoms questionnaire spirometry.(a) Wheezing: Affirmative answer question "have you ever had two or more...
OBJECTIVE: Wood smoke exposure is a risk factor for COPD. For given degree of airway obstruction, the reduction in DLCO smaller individuals with wood smoke-related COPD than those smoking-related COPD, suggesting that there less emphysema former. The objective this study was to compare HRCT findings between women and METHODS: Twenty-two severe (FEV1/FVC ratio < 70% FEV1 50%) were divided into two groups: (n = 12) 10). groups compared regarding scores involvement (as determined by HRCT);...
Was to describe 14 cases of a proliferative verrucous leukoplakia as clinical evolution oral lichen planus.The and histopathological characteristics OLP that progress towards plaque-like form were indicated, with monitoring over period six 24.3 years.The female/male ratio was 11/3, (78.6 21.4%). The mean age when the first biopsy undertaken 56.4 years old. None patients smoked during study. As bilateral reticular clinically diagnostic criterion, second most frequent plaque (n=10; 71.4%),...
Purpose: Chronic obstructive pulmonary disease (COPD) related to wood smoke exposure is characterized by important inflammation of the central and peripheral airways without significant emphysema. The objective this study describe bronchial hyperresponsiveness (BHR) level in women with COPD compare it BHR tobacco smoking. Materials methods: Two groups stable were studied: (1) exposed (WS-COPD); (2) (TS-COPD). A methacholine challenge test (MCT) was performed all patients according American...
COPD prevalence is highly variable and geographical altitude has been linked to it, yet with conflicting results. We aimed investigate this association, considering well known risk factors. A pooled analysis of individual data from the PREPOCOL-PLATINO-BOLD-EPI-SCAN studies was used disentangle population effect on prevalence. Post-bronchodilator FEV1/FVC below lower limit normal defined airflow limitation consistent COPD. High as >1500 m above sea level. Undiagnosed considered when...
REM-associated OSA (REM OSA) has a prevalence of 17-74% all cases. At high altitude and in Latin America, there are no data on REM its relationship to daytime sleepiness comorbidities. This study aimed determine the differences clinical polysomnographic characteristics between population living at 2640 m. A retrospective cross-sectional was conducted adults Bogotá, Colombia January December 2022. Patients were considered have REM- if they had sleep duration least 30 minutes ratio REM-AHI...
Idiopathic pulmonary fibrosis (IPF) is the most common Interstitial Lung Disease (ILD). It characterized by dyspnoea and a progressive decline in lung function, which negatively affects life. This study aimed to evaluate Health-Related Quality of Life (HRQoL) IPF patients Latin American countries. Six countries (Argentina, Bolivia, Colombia, Chile, Mexico, Dominican Republic) enrolled with IPF. They answered Saint George's Respiratory Questionnaire for Pulmonary Fibrosis (SGRQ-I) Hospital...
Asthma and chronic obstructive pulmonary disease overlap patients (ACO) have more exacerbations a worse prognosis than pure asthma or COPD, it is of great interest to identify differential biomarkers ACO. We compared blood eosinophil counts, plasma IgE protein levels among with asthma, ACO, healthy subjects those associated 397 adults (age 40-90 years) were recruited from two Colombian cities: (n=123), COPD (n=100), ACO (n=74) control (HC, n=100). Plasma measured using the Proximity...
Abstract The queen snapper ( Etelis oculatus Valenciennes in Cuvier & Valenciennes, 1828) is a deep-sea whose commercial importance continues to increase the US Caribbean. However, little known about biology and ecology of this species. In study, presence fine-scale population structure genetic diversity from Puerto Rico was assessed through 16,188 SNPs derived Restriction site Associated DNA Sequencing (RAD-Seq) technique. Summary statistics estimated low (HO = 0.333–0.264) did not...
Introduction. International asthma management and prevention recommendations emphasize the importance of early accurate diagnosis adequate disease control. However, these aspects remain a serious concern, especially in children with low socioeconomic status.Objective. To describe prevalence, underdiagnosis, severity, control among status Bogotá, Colombia.Materials methods. We conducted cross-sectional study using Study Asthma Allergies Questionnaire aged 7-11 two public schools. The...
Objective: To determine the prevalence of viral and atypical bacteria Mycoplasma pneumoniae infection in children experiencing asthma exacerbation compare positive negative subjects with regard to severity, need for hospitalization, treatment. Methods: One hundred sixty-nine asthmatic aged 2–15 years old who were admitted emergency rooms Bogota, Colombia acute interviewed. Nasopharyngeal aspirates taken DNA RNA extraction. M. virus detected by PCR using specific primers. Results: The study...
We report a case of acute cholestatic hepatitis in an immunocompetent young male with cytomegalovirus (CMV) primoinfection episode. The severity the clinical symptoms led to high-dose treatment parenteral ganciclovir, immediate response and total resolution symptoms. Therapeutic options are discussed, particularly use even patients when could demand it.
Pulmonary hypertension (PH) is associated with poor prognosis for patients chronic obstructive pulmonary disease (COPD). Most of the knowledge about PH in COPD has been generated at sea level, limited information high altitude (HA). To assess prevalence and severity living a HA city (2,640 m). Cross-sectional study forced expiratory volume first second / vital capacity ratio (FEV1/FVC) post-bronchodilator <0,7. Transthoracic echocardiography (TTE), spirometry, carbon monoxide diffusing...
González-García, Mauricio and Luis Ernesto Téllez. Adaptation to living at high altitude in patients with COPD. Comparative study of exercise capacity ventilatory variables between residing low altitudes the Andes. High Alt Med Biol. 00:000–000, 2024. Introduction: Although some related oxygen transport utilization such as ventilation, pulmonary vascular responses hypoxia, heart rate (HR), cardiac output, hemoglobin (Hb), saturation (SpO2) are used compare adaptation populations, peak...
The objective of the article was to establish prevalence, underdiagnosis, and risk factors chronic bronchitis (CB) in a general population five Colombian cities. Cross-sectional study using probabilistic sampling technique cities adopted. CB definition “cough expectoration for three or more months per year at least two consecutive years.” Underdiagnosis considered subjects with clinical without previous medical diagnosis. Univariate χ 2 Student’s t-test logistic regression analysis were...
Exercise intolerance, desaturation, and dyspnea are common features in patients with chronic obstructive pulmonary disease (COPD). At altitude, the barometric pressure (BP) decreases, therefore inspired oxygen partial of arterial (PaO2) also decrease healthy subjects even more COPD. Most studies evaluating ventilation blood gas (ABG) during exercise COPD have been conducted at sea level small populations people ascending to high altitudes. Our objective was compare capacity, exchange,...