A5037554512- Chronic Disease Management Strategies
- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Primary Care and Health Outcomes
- Diabetes Management and Education
- Medication Adherence and Compliance
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 and Mental Health
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Clinical practice guidelines implementation
- Helicobacter pylori-related gastroenterology studies
- Interprofessional Education and Collaboration
- Hip and Femur Fractures
- Health and Medical Studies
- Diverticular Disease and Complications
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Liver Disease Diagnosis and Treatment
- Physical Activity and Health
- Cardiovascular Effects of Exercise
- Chemotherapy-related skin toxicity
- Colorectal Cancer Screening and Detection
- Hemodynamic Monitoring and Therapy
- Geriatric Care and Nursing Homes
- Gastrointestinal disorders and treatments
Paracelsus Medical University
2016-2025
University of Salzburg
2022-2023
Paracelsus Medizinische Privatuniversität
2018-2021
Committee on Publication Ethics
2020
Universität für Weiterbildung Krems
2013-2014
Universitätsklinikum Krems
2013
Kinokuniya
2012
New York University Press
2012
Columbia University Irving Medical Center
2011
University of Rostock
2011
Disease management programmes (DMPs) are costly and impose additional work load on general practitioners (GPs). Data their effectiveness inconclusive. We therefore conducted a cluster-randomised controlled trial to evaluate the of Austrian DMP for diabetes mellitus type 2 HbA1c quality care adult patients in primary care. All GPs Salzburg-province were invited participate. After cluster-randomisation by district, all with recruited consecutively from 7-11/2007. The DMP, consisting mainly...
Self-management support is a key component of effective chronic care management, yet in practice appears to be the least implemented and most challenging. This study explores whether how self-management integrated into approaches 13 European countries. In addition, it investigates level barriers implementation strategies health practice. We conducted review among participating countries, based on common data template informed by Chronic Care Model. Key informants presented sample...
Chronic diseases affect more than half of the population ≥75 years age in developed countries. Prescription medication use increases with age. Depending on definition, 25–80% elderly are exposed to polypharmacy. Polypharmacy risk hospitalization, interactions and adverse drug reactions. To examine frequency errors patients polypharmacy treated general practice. The medications 169 22 GP surgeries Austria were analysed. analysis identified (i) errors, including non-evidence-based medications,...
Abstract Objective To evaluate the effects of a computerised decision support tool for comprehensive drug review in elderly people with polypharmacy. Design Pragmatic, multicentre, cluster randomised controlled trial. Setting 359 general practices Austria, Germany, Italy, and United Kingdom. Participants 3904 adults aged 75 years older using eight or more drugs on regular basis, recruited by their practitioner. Intervention A newly developed electronic comprising to practitioners...
Multimorbidity is increasing in aging populations with a corresponding increase polypharmacy as well inappropriate prescribing. Depending on definitions, 25-50 % of patients aged 75 years or older are exposed to at least five drugs. Evidence that polypharmacy, even when guidelines advise the prescribing each drug individually, can potentially cause more harm than benefit patients, due factors such drug-drug and drug-disease interactions. Several approaches reducing have been proposed, but...
Rheumatoid arthritis (RA) is a chronic autoimmune disease marked by systemic inflammation. While RA primarily affects the joints, its effects may lead to an increased cerebro- and cardiovascular risk. Atherosclerosis of carotid arteries significant risk factor for cerebrovascular events serves as surrogate marker This study explores link between artery atherosclerosis with data from Paracelsus 10,000 Study. Baseline assessments were conducted on individuals randomly selected Salzburg...
Patients do not always receive guideline-adherent therapy, yet little is known about the underlying causes on patients' side. We quantified non-guideline-adherent treatment of chronic diseases (diabetes mellitus, hypertension, cardiovascular disease, heart failure, atrial fibrillation) in primary care and analysed from physician's as well patient's view.With intention to analyze frequency patients with diseases, we drew a random sample 124 general practitioners (GP) Salzburg, Austria, which...
Background Laboratory tests, electrocardiogram ( ECG ) and chest X ‐rays still serve as part of the routine assessment before elective surgery in many institutions, even though there is little evidence their predictive value relating to perioperative complications. This study investigates correlation abnormal findings pre‐operative tests pathologic medical history with Methods Patients scheduled for a secondary care hospital were included this prospective cohort study. Abnormal significant...
Abstract Background Persons with dementia (PwD) need support to remain in their own homes as long possible. Family caregivers, homecare nurses and general practitioners (GPs) play an important role providing this support, particularly rural settings. Assessing caregiver burden is prevent adverse health effects among population. This study analysed perceived needs of family caregivers PwD areas from the perspectives healthcare professionals caregivers. Methods was a sequential explanatory...
Abstract Background Uncoordinated interprofessional communication in nursing homes increases the risk of polypharmacy and inappropriate medication use. This may lead to augmented frequency adverse drug events, hospitalizations mortality. The aims this study were (1) improve safety using a combined intervention thus, (2) appropriateness health-related outcomes included residents. Methods single-arm interventional (2014–2017) was conducted Muenster, Germany involved healthcare professionals...
Background Coronavirus disease 2019 (COVID-19) represents a significant challenge to health care systems around the world. A well-functioning primary system is crucial in epidemic situations as it plays an important role development of system-wide response. Methods 2,187 Austrian and German GPs answered internet survey on preparedness, testing, staff protection, perception risk, self-confidence, decrease number patient contacts, efforts control spread virus practice during early phase...
Abstract Purpose Post-COVID-19-Syndrome (PCS) frequently occurs after an infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, the understanding of causative mechanisms is still limited. Aim this study was to determine PCS rate among SARS-CoV-2 seropositive blood donors as representatives supposedly healthy adults, who had experienced asymptomatic or mild COVID-19 disease course, and examine whether Epstein-Barr virus (EBV) reactivated in individuals reporting...
To date, DNA-binding factors with a developmental pattern of expression have not been described in human erythroid cells to explain the switch from fetal (gamma-) adult (delta- and beta-) globin gene expression. Here we describe factor present nuclear extracts mouse hematopoietic that binds an oligopyrimidine repeat approximately 960 base pairs upstream delta-globin gene. The binding site for is within unusual 250-base-pair domain greater than 95% pyrimidines on one strand. This...
COPD prevalence is highly variable and geographical altitude has been linked to it, yet with conflicting results. We aimed investigate this association, considering well known risk factors. A pooled analysis of individual data from the PREPOCOL-PLATINO-BOLD-EPI-SCAN studies was used disentangle population effect on prevalence. Post-bronchodilator FEV1/FVC below lower limit normal defined airflow limitation consistent COPD. High as >1500 m above sea level. Undiagnosed considered when...
Dementia is a progressive disease that puts substantial strain on caregivers. Many persons with dementia (PwDs) receive care from relative. Since male and female caregivers experience different issues related to stress, it important meet their needs prevent the early nursing home placement of PwDs. This study investigated multifactorial aspects caregiver burden explored gender differences in rural setting. was cross sectional administered anonymous questionnaires family Caregiver assessed...
Abstract Objectives Helicobacter pylori ( H. ) and cardiovascular (CV) disease share common symptoms underlie many general medical complaints. Preliminary studies suggest an association between positivity CV risk, gastroenterological guidelines recommend eradication of in patients with manifest atherosclerosis. Therefore, the aim this study was to examine reciprocal risk for their independence shared factors. Methods We included 3284 asymptomatic participants a colorectal cancer screening...
Abstract Introduction Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality. SCORE2 may underestimate risk in those classified as low-to-moderate risk. Polygenic scores (PGS) capture genetic predisposition to CVD could enhance traditional models. This study examines whether integrating PGS with improves the prediction significant subclinical coronary atherosclerosis, defined artery calcium (CAC) >100. Methods We analyzed data from 1,420 participants...