- Retinal Diseases and Treatments
- Reproductive tract infections research
- Intraocular Surgery and Lenses
- Complement system in diseases
- Reproductive System and Pregnancy
- Galectins and Cancer Biology
- Substance Abuse Treatment and Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Glycosylation and Glycoproteins Research
- Natural Antidiabetic Agents Studies
- Pharmaceutical studies and practices
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Glaucoma and retinal disorders
- Vestibular and auditory disorders
- HIV, Drug Use, Sexual Risk
- Cell Adhesion Molecules Research
- Retinal Imaging and Analysis
- Adipokines, Inflammation, and Metabolic Diseases
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Retinal and Macular Surgery
- Global Health and Surgery
- Signaling Pathways in Disease
- Inflammatory mediators and NSAID effects
- Genetic Associations and Epidemiology
Guru Nanak Dev University
2014-2024
Aravind Eye Hospital
2003-2024
Unitec Institute of Technology
2024
Lovely Professional University
2024
Government Medical College, Amritsar
2011-2022
Uniformed Services University of the Health Sciences
2021
Wayne State University
2009-2020
University Hospitals of North Midlands NHS Trust
2020
Yale University
2018
University of Pittsburgh
2015-2017
Piperine, a major active component of black and long peppers, has been reported to enhance drug bioavailability. The present studies were aimed at understanding the interaction piperine with enzymatic biotransforming reactions in hepatic tissue vitro vivo. Piperine inhibited arylhydrocarbon hydroxylation, ethylmorphine-N-demethylation, 7-ethoxycoumarin-O-deethylation 3-hydroxy-benzo(a)pyrene glucuronidation rat postmitochondrial supernatant dose-dependent manner. inhibition these from...
We characterized the role of structural variants, a largely unexplored type genetic variation, in two non-Alzheimer's dementias, namely Lewy body dementia (LBD) and frontotemporal (FTD)/amyotrophic lateral sclerosis (ALS). To do this, we applied an advanced variant calling pipeline (GATK-SV) to short-read whole-genome sequence data from 5,213 European-ancestry cases 4,132 controls. discovered, replicated, validated deletion
Acamprosate with dual mechanism of action as glutamate antagonist and GABA agonist can be a potential target to decrease the severity sensorineural tinnitus.(1)To study effectiveness acamprosate in providing subjective relief objective improvement patients having tinnitus origin. (2) To evaluate adverse events related use also determine change quality life (QOL) parameters.The was randomized double-blind, placebo controlled, crossover. Forty adult subjects (>18 years age), either sex origin,...
Abstract Background: The current standard treatment for sudden sensorineural hearing loss (SSNHL) comprises of tapered course oral corticosteroids. Intratympanic steroids are introduced as another modality treatment, but management SSNHL continues to be debatable. present study was designed evaluate the efficacy given orally and by intratympanic route. Methods: A prospective, randomized, open-labeled conducted involving 42 patients. These were randomly divided into two groups; group I...
The bgl operon of Escherichia coli is transcriptionally inactive in wild‐type cells. DNA insertion sequences (IS) constitute a major class spontaneous mutations that activate the cryptic promoter. In an attempt to study molecular mechanism activation mediated by sequences, transcription promoter was carried out vitro . Stimulation observed when plasmid containing insertionally activated used as template absence proteins other than RNA polymerase. Deletions remove upstream promoter, and 1.2...