A5100674297- Nanoparticle-Based Drug Delivery
- Muscle and Compartmental Disorders
- Global Cancer Incidence and Screening
- Breastfeeding Practices and Influences
- Ocular Diseases and Behçet’s Syndrome
- Microfluidic and Capillary Electrophoresis Applications
- Musculoskeletal pain and rehabilitation
- Cancer-related Molecular Pathways
- Ocular Infections and Treatments
- Thyroid Disorders and Treatments
- Glaucoma and retinal disorders
- HER2/EGFR in Cancer Research
- Oral and Maxillofacial Pathology
- Microfluidic and Bio-sensing Technologies
- Ocular Surface and Contact Lens
- Congenital Anomalies and Fetal Surgery
- Heterotopic Ossification and Related Conditions
- Aerosol Filtration and Electrostatic Precipitation
- Cancer Research and Treatments
- Pain Mechanisms and Treatments
- Advances in Oncology and Radiotherapy
- Advanced Drug Delivery Systems
- Healthcare and Venom Research
- Parathyroid Disorders and Treatments
- Intraocular Surgery and Lenses
Huazhong University of Science and Technology
1993-2025
Tianjin Medical University
2022
United States Food and Drug Administration
2021
Center for Drug Evaluation and Research
2021
Guangdong Medical College
2021
Xuzhou Medical College
2021
Dalian Medical University
2020
Chongqing Medical University
2020
Second Affiliated Hospital of Chongqing Medical University
2020
Nanjing Drum Tower Hospital
2019
First-generation KRAS inhibitors, sotorasib and adagrasib, are approved for treating non-small cell lung cancer colorectal with specific mutations. This study analyzed data from FAERS database to evaluate adverse events (AEs) associated inhibitors. Four disproportionality analysis methods were applied measure risk signals: reporting odds ratio (ROR), proportional (PRR), bayesian confidence propagation neural network (BCPNN), multi-item gamma poisson shrinker (MGPS) algorithms. Between Q2...
Electroacupuncture (EA) has anti-oxidative and anti-inflammatory actions, but whether the neuroprotective effect of EA against cerebral ischemia-reperfusion (I/R) injury involves modulation extracellular regulated kinase 1/2 (ERK1/2) signaling pathway is unclear. Middle artery occlusion (MCAO) was performed in Sprague-Dawley rats for 2 hours followed by reperfusion 24 hours. A 30-minute period stimulation applied to both Baihui (DU20) Dazhui (DU14) acupoints each rat (10 mm penetration...
Prodrug–carboxypeptidase G2 (e.g., ZD2767P+CPG2) can realize a targeted treatment where the specific advantage is lack of CPG2 analogues in humans, but it limited by low efficacy. Here ultrasound was employed to enhance ZD2767P+CPG2 (i.e., ZD2767P+CPG2+US) against chemoresistant human ovarian cancer cells. The release dynamics ZD2767D (activated drug) were investigated. vitro efficacy explored SKOV3 and SKOV3/DDP (cisplatin-resistant subline) cells; spectrophotometry established quantify...
Increasing evidence has shown that nanocarriers have effects on several efflux drug transporters. To date, little is known about whether influx transporters are also modulated. Herein, we investigated the impact of amphiphilic polymer micelles uptake function organic cation (OCTs) and influence pharmacokinetics pharmacodynamics metformin, a well-characterized substrate OCTs. Five types polymeric (mPEG2k-PCL2k, mPEG2k-PCL3.5k, mPEG2k-PCL5k, mPEG2k-PCL7.5k, mPEG2k-PCL10k) were prepared to...
Abstract Background The outbreak of COVID-19 pandemic in China has greatly impacted the radiotherapy (RT) strategy for breast cancer (BC) patients, which might lead to an increased distressing psychological symptom. Thus, we perform a multi-center cross-section survey aiming investigate prevalence fears recurrence (FCR) and explore predictors FCR BC patients referred RT during pandemic. Methods: 542 who between 24th Jan 30th April 2020 were consecutively enrolled from 14 hospitals around...