Huan Huang

ORCID: 0000-0001-9220-3910
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Research Areas
  • Lung Cancer Research Studies
  • Gynecological conditions and treatments
  • Cancer Treatment and Pharmacology
  • Uterine Myomas and Treatments
  • Neutropenia and Cancer Infections
  • Advanced Breast Cancer Therapies
  • Breast Cancer Treatment Studies
  • Antibiotic Resistance in Bacteria
  • Reproductive System and Pregnancy
  • Asthma and respiratory diseases
  • Endometriosis Research and Treatment
  • Intestinal and Peritoneal Adhesions
  • HER2/EGFR in Cancer Research
  • Sexual function and dysfunction studies
  • Reproductive tract infections research
  • Diabetes Treatment and Management
  • Genital Health and Disease
  • Diabetes Management and Research
  • Chronic Myeloid Leukemia Treatments
  • Rheumatoid Arthritis Research and Therapies
  • Medication Adherence and Compliance
  • Acute Myeloid Leukemia Research
  • Pneumonia and Respiratory Infections
  • Head and Neck Cancer Studies
  • Myeloproliferative Neoplasms: Diagnosis and Treatment

Zhejiang International Studies University
2025

Chengdu University of Technology
2025

Central South University
2017-2023

Third Xiangya Hospital
2017-2023

G1 Therapeutics (United States)
2021-2023

Triangle
2021-2023

Weatherford College
2023

IQVIA (United States)
2015-2022

Renji Hospital
2017-2020

Shanghai Jiao Tong University
2014-2020

Intrauterine adhesion (IUA) prevalence is difficult to measure, but appears have increased over the last few decades. The reproductive outcomes following hysteroscopic adhesiolysis (HA) for moderate-severe IUAs were unsatisfactory, and studies analyzed clinical characteristics pre-, intra- post-HA determine main risk factors infertility in patients with IUAs.This retrospective observational study included 406 patients, desiring fertility, who had undergone HA between January 1st, 2016 May...

10.21037/atm.2019.11.115 article EN Annals of Translational Medicine 2020-02-01

The objective of this study was to explore the association between disordered vaginal microbiota and missed abortion ascertain potential causes related microbiology.This a prospective cohort with comparison group (reference group). Vaginal secretions from posterior fornix women in early stages pregnancy were collected Xiangya Third Hospital Central South University Changsha, Hunan, China, November 2018 2019. A total 54 cases (case group) 50 normal requiring induced analyzed. Bacterial DNA...

10.1111/aogs.14410 article EN cc-by-nc-nd Acta Obstetricia Et Gynecologica Scandinavica 2022-07-24

Iatrogenic injury to endometrial tissue is the main cause of intrauterine adhesions (IUA) and infection can also damage endometrium. The microbiota plays an important role in health female reproductive tract. However, mechanism still unclear. In total, 908 patients with IUA 11,389 healthy individuals were retrospectively selected for this clinical study. Participant information including vaginal microecological results human papillomavirus (HPV) status collected. Univariate multivariate...

10.1038/s41598-022-25471-0 article EN cc-by Scientific Reports 2023-01-11

Abstract With the continuous acceleration of social rhythm, health quality and problems public have become more prominent, physical exercise has been increasingly emphasized as a mainstream means to enhance benefits groups. In order explore impact activity on group benefits, this paper puts forward research hypotheses, determines data sources methods, eliminates bias caused by self-selection with help propensity score matching, combines Bivariate Probit model two-stage least squares put...

10.2478/amns-2025-0467 article EN Applied Mathematics and Nonlinear Sciences 2025-01-01

This study is the first to use Bayesian Estimator of Abrupt Change, Seasonality, and Trend (BEAST) algorithm detect trend change points in nexuses between green bond index (Green Bond) WTI crude oil, gasoline, as well natural gas futures. The COVID-19 pandemic Russia–Ukraine war are identified common significant points, total sample subsequently divided into three stages based on these points. Utilizing a skewed MF-DCCA method, this analyzed multifractal characteristics Green Bond energy...

10.3390/fractalfract9050327 article EN cc-by Fractal and Fractional 2025-05-20

BackgroundTyrosine-kinase inhibitors (TKIs) can be associated with vascular events (VEs). The expected VE rates in patients chronic myeloid leukemia (CML) are unknown. present study examined the event and mortality among elderly without CML.Materials MethodsLinked Surveillance, Epidemiology, End Results cancer registry Medicare claims data were used to identify aged ≥ 66 years an incident (index) diagnosis of CML from 2004 2009. A comparison cohort was matched 1:1 cohort. All followed up 12...

10.1016/j.clml.2016.01.006 article EN cc-by-nc-nd Clinical Lymphoma Myeloma & Leukemia 2016-02-07

Intrauterine adhesion (IUA) is one of the most important causes female infertility, while iatrogenic endometrial injury main, but not entire, cause IUA. The microorganisms reproductive tract play an role in its health and disease. imbalance immune regulation caused by dysbacteriosis may be link formation mechanism uterine cavity adhesion.We prospectively enrolled 30 patients diagnosed with IUA women a history intrauterine surgery, without IUA, as control subjects. All participants were...

10.21037/atm.2019.11.124 article EN Annals of Translational Medicine 2020-02-01

Background: Intrauterine adhesion (IUA), also referred to as Asherman syndrome, is a complication with partial or complete of the uterine cavity due fibrotic proliferation after endometrial and wall injury newly pregnant uterus. Currently, all IUA research models are based on non-pregnant animals which ill-suited in mimicking its pathogenesis. This study aimed establish an animal model caused by surgical abortion curettage rats that more line clinical etiology, provide ideal for further...

10.21037/atm.2020.01.134 article EN Annals of Translational Medicine 2020-02-01

BackgroundU.S. guidelines recommend that patients with severe asthma be referred to specialists (allergists/immunologists or pulmonologists) for systematic assessment comanagement; however, contemporary, real-world data on the frequency and impact of specialist care among U.S. are lacking.ObjectivesTo quantify visits asthma, identify patient demographic clinical characteristics associated describe health outcomes following care.MethodsSevere aged 6 years older were identified between January...

10.1016/j.jaip.2021.05.003 article EN cc-by-nc-nd The Journal of Allergy and Clinical Immunology In Practice 2021-06-17

Intrauterine adhesion (IUA) is caused by of the uterine cavity due to damage endometrium. Hysteroscopic adhesiolysis (HA) main treatment. The objective study was investigate obstetrical outcome in third trimester women who previously underwent HA.We performed a retrospective cohort university-affiliated hospital. A total 146 with history HA had given birth their from May 2012 2019 were enrolled (study group), while 292 negative matched for maternal age, gravidity, parity, and delivery year....

10.21037/atm.2019.09.123 article EN Annals of Translational Medicine 2020-02-01

Objective The pregnancy patterns and other factors of live birth for patients with intrauterine adhesions (IUAs) were identified by analyzing the clinical features pre-, intra-, post-hysteroscopic adhesiolysis (HA). Design A total 742 IUAs who wanted to become pregnant underwent HA from January 2017 May 2018 at Third Xiangya Hospital Central South University. patient follow-up period was 2 years post-HA. logistic regression performed analyze characteristics associated a IUAs. Pre-operative...

10.3389/fphys.2022.822845 article EN cc-by Frontiers in Physiology 2022-03-11

The prevalence of Klebsiella pneumonia bloodstream infections (KP-BSIs) is increasing worldwide. Few study reports focus on the KP-BSIs published in Mainland China over previous years. This aimed to describe risk factors mortality from KP-BSIs.A retrospective was conducted a teaching hospital Shanghai, China, for period 4 Risk related patient were analyzed using binary logistic regression model.Of 104 patients with KP-BSIs, overall 30-day rate 25%. analysis revealed that thrombocytopenia...

10.1097/md.0000000000007924 article EN cc-by-nc Medicine 2017-08-29

Abstract This cross-sectional study investigated the characteristics of cervical HPV infection in Changsha area and explored influence Candida vaginitis on this infection. From 11 August 2017 to September 2018, 12,628 outpatient participants ranged from 19 84 years old were enrolled analyzed. DNA was amplified tested by GenoArray Test Kit. The vaginal ecology detected microscopic biochemistry examinations. diagnosis based examination (spores, and/or hypha) biochemical testing (galactosidase)...

10.1038/s41598-021-94635-1 article EN cc-by Scientific Reports 2021-07-23

Background: Biliary tract infection (BTI) is a common cause of bacteremia, and associated with high morbidity mortality. The clinical epidemiology outcomes BTI caused by Klebsiella pneumoniae ( KP ) have not been well investigated. Methods: This was retrospective study performed at university teaching hospital in China from May 2012 to June 2017 that analyzed data for 119 patients KP. We identified bile cultures obtained before endoscopic or surgical treatment. Patients' demographic...

10.21037/atm.2019.06.03 article EN Annals of Translational Medicine 2019-07-01

Intrauterine adhesions (IUAs), also known as Asherman syndrome, was first reported by in 1894 (1). The prevalence ranges from 1.73% to 40%, and the symptoms include hypomenorrhea, amenorrhea, periodic lower quadrant abdominal pain. IUAs affect pregnancy, having various presentations; for example, infertility, repeated pregnancy loss, poor implantation, abnormal placentation (2-6). Surgery has been standard treatment choice management of syndrome. Since surgical wounds are prone re-adhesion,...

10.21037/atm.2019.12.82 article EN Annals of Translational Medicine 2020-02-01

Management of intrauterine adhesions (IUAs) is challenging, mainly because there no ideal method to prevent its recurrence. Recurrence moderate severe IUAs after conventional treatments entails a poorer prognosis in these patients. This study aimed assess the safety and effectiveness patented stent as barrier treatment recurrent with poor prognosis.This was retrospective, observational 13 women IUAs, admitted Third Xiangya Hospital Central South University from June 2018 September 2019....

10.21037/atm.2020.01.77 article EN Annals of Translational Medicine 2020-02-01

Abstract Introduction Treatments for Peyronie's disease (PD) include surgical management and collagenase clostridium histolyticum (CCH). Aims To evaluate PD treatment trends after CCH approval compare clinical outcomes in CCH- surgery-treated cohorts. Methods Patients newly diagnosed with between January 2011 December 2017 were identified a U.S. claims database. Cohorts initiating or surgery 2014 June included. continuously enrolled ≥6 months before ≥12 index date. Post-treatment penile...

10.1016/j.esxm.2021.100321 article EN cc-by Sexual Medicine 2021-03-05

Journal Article Klebsiella pneumoniae sepsis with unusual cutaneous presentation of generalized pustulosis Get access H. Y. Huang, Huang Department Dermatology Mackay Memorial Hospital Taipei Taiwan Search for other works by this author on: Oxford Academic Google Scholar Wu, Wu TaiwanMackay Medicine Nursing and Management College Medical New City Correspondence: Dr Yu‐Hung 92, Sec. 2, Zhongshan N. Road, District, Taipei, 10449, E‐mail: yuhung_wu@yahoo.com C. F. Kuo Division Infectious...

10.1111/ced.12092 article EN Clinical and Experimental Dermatology 2013-07-10

To estimate the proportion of patients with moderate to severe chronic kidney disease (CKD) whose initial dipeptidyl-peptidase-4 inhibitor (DPP4-i) dosage was concordant prescribing information (label) recommendations in United States.Adult type 2 diabetes mellitus (T2DM) who initiated a DPP4-i (linagliptin, sitagliptin, saxagliptin) between 1 January 2011 and 30 June 2014 were identified using electronic medical records administrative claims, index date being first observed treatment....

10.1080/03007995.2017.1416346 article EN Current Medical Research and Opinion 2017-12-12

This study aims at investigating the effect of growth hormone (GH) on human endometrial glandular cells (hEGCs) and preliminary exploring its mechanism.HEGCs were isolated from biopsies exposed to different dose GH (0, 50, 100, 200 ng/mL). Cell proliferation cell cycle assay, migration assay was performed investigate motivation hEGCs, respectively. Reverse transcription-polymerase chain reaction (RT-PCR), immunocytochemistry (ICC), western blot (WB) processed related gene or protein...

10.21037/atm.2019.12.08 article EN Annals of Translational Medicine 2020-02-01

Abstract Background Few studies have evaluated survival, treatment, resource use, and costs among women with stage IV ER + breast cancer (BC) who did not receive HER2 targeted therapy. Methods Using linked Surveillance, Epidemiology, End Results (SEER) Medicare data from 2006-2009, aged 66+ years an incident diagnosis of BC (index date) in 2007 no therapy were identified. A comparison cohort without was created the SEER 5% sample matched 1:1 to study based on age, sex, race. All patients had...

10.1186/1472-6963-14-298 article EN cc-by BMC Health Services Research 2014-07-09
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