- Musculoskeletal pain and rehabilitation
- Pain Mechanisms and Treatments
- Pain Management and Placebo Effect
- Pain Management and Opioid Use
- Botulinum Toxin and Related Neurological Disorders
- Opioid Use Disorder Treatment
- Health, Medicine and Society
- Digital Mental Health Interventions
- Anesthesia and Pain Management
- Healthcare Systems and Practices
- Migraine and Headache Studies
- Treatment of Major Depression
- Parkinson's Disease Mechanisms and Treatments
- Trigeminal Neuralgia and Treatments
- Poisoning and overdose treatments
- Urinary Tract Infections Management
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sexual function and dysfunction studies
- Male Breast Health Studies
- Intramuscular injections and effects
- Psychedelics and Drug Studies
- Pneumothorax, Barotrauma, Emphysema
- Antibiotic Resistance in Bacteria
- Cancer Treatment and Pharmacology
- Dental Anxiety and Anesthesia Techniques
Centre Hospitalier Universitaire de Toulouse
2007-2024
Université de Toulouse
2009-2024
Hospices Civils de Lyon
2005-2019
Hôpital Paule de Viguier
2018-2019
Pharmacochimie et Pharmacologie pour le Développement
2019
Hôpital Rangueil
2004-2014
Hôpital de La Grave
2005
Background Long-term opioid use is associated with pharmacological tolerance, a risk of misuse and hyperalgesia in patients chronic pain (CP). Tapering challenging this context, particularly comorbid opioid-use disorder (OUD). The antihyperalgesic effect ketamine, through N-methyl-D-aspartate (NMDA) antagonism, could be useful. We aimed to describe the changes dose opioids consumed over 1 year after 5-day hospitalisation ketamine infusion for CP OUD. Methods performed historical cohort study...
Chronic pain affects approximately 30% of the general population, severely degrades quality life (especially in older adults) and professional (inability or reduction ability to work loss employment), leads billions additional health care costs. Moreover, available painkillers are old, with limited efficacy can cause significant adverse effects. Thus, there is a need for innovation management chronic pain. Better characterization patients could help identify predictors successful treatments,...
Public health issues related to chronic pain management and the risks of opioid misuse abuse remain a challenge for practitioners. Data on prevalence disorders use prescribed opioids in patients suffering from remains rather patchy, particular because absence gold standard their clinical assessment. We estimated prescription (POM), using specific validated scale (POMI-5F scale), adults with non-cancer pain. Nine-hundred-fifty-one (951) followed-up clinics addictology centers (CNCP) completed...
Aim: Patients with chronic non-cancer pain are referred to centres improve their treatment. The discontinuation of medications in case poor efficacy can be difficult accept for patients, particularly opioid analgesics. Previous research has described that from the patients' perspective, psychological relief a negative effect and withdrawal symptoms prescription opioids represent drivers persistent use first stage disorder, despite insufficient relief. There is no validated tool investigate...
Background Chronic pain affects approximately 30% of the general population, severely degrades quality life and professional life, leads to additional health care costs. Moreover, medical follow-up patients with chronic remains complex provides only fragmentary data on painful daily experiences. This situation makes management less than optimal may partly explain lack effectiveness current therapies. Real-life monitoring subjective objective markers using mobile (mHealth) programs could...
<sec> <title>BACKGROUND</title> Chronic pain affects approximately 30% of the general population, severely degrades quality life and professional life, leads to additional health care costs. Moreover, medical follow-up patients with chronic remains complex provides only fragmentary data on painful daily experiences. This situation makes management less than optimal may partly explain lack effectiveness current therapies. Real-life monitoring subjective objective markers using mobile...