A5101563201- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Graphene and Nanomaterials Applications
- Cardiovascular Health and Disease Prevention
- Inflammatory Biomarkers in Disease Prognosis
- Additive Manufacturing and 3D Printing Technologies
- Advanced biosensing and bioanalysis techniques
- Mesenchymal stem cell research
- Antiplatelet Therapy and Cardiovascular Diseases
- Nanoplatforms for cancer theranostics
- Molecular Communication and Nanonetworks
Chinese PLA General Hospital
2019-2024
Chinese People's Armed Police Force
2016
Chinese People's Armed Police General Hospital
2016
Police General Hospital
2014
Tissue engineering exploring the combination of scaffolds and seeding cells was proposed as a promising strategy for myocardial repair. However, therapeutic outcomes varied greatly due to different selection cells. Herein, potential combining bioactive extracellular matrix (ECM) hydrogels high cardiomyogenic explored repair in vitro vivo. Temperature-sensitive ECM were prepared from decellularized rat hearts, isolated brown adipose (brown adipose-derived stem (BADSCs)). The studies...
Stimuli-responsive nanoparticles (NPs), so-called "smart" NPs, possess great potentials in drug delivery. Presently, the intelligence of smart NPs is mainly based on their chemical or physical changes to stimuli, which are usually "mechanical" and fundamentally different from biological intelligence. Inspired by mitochondria (MT), a biosmart nanoparticle with microenvironment targeting self-adaptive capacity (MTSNP) was fabricated for ischemic tissue repair. The were designed as...
Abstract Background The niche of tissue development in vivo involves the growth matrix, biophysical cues and cell-cell interactions. Although natural extracellular matrixes may provide good supporting for seeding cells vitro, it is evitable to destroy during decellularization. Reconstructing bioactivities matrix-based scaffolds essential their usage repair. Results In study, a hybrid hydrogel was developed by incorporating single-wall carbon nanotubes (SWCNTs) into heart-derived matrixes....
Cardiac tissue engineering (CTE) has developed rapidly, but a great challenge remains in finding practical scaffold materials for the construction of engineered cardiac tissues. Carbon nanohorns (CNHs) may be potential candidate due to their special structure and properties. The purpose this study was assess effect CNHs on biological behavior neonatal rat ventricular myocytes (NRVMs) CTE applications. were incorporated into collagen form growth substrates NRVMs. Transmission electron...
Background The necrosis of a large number myocardial cells after acute infarction (AMI) results in decrease cardiac function and ventricle remodeling. Stem cell transplantation could improve AMI, but the involving mechanisms have not been completely understood. present study aimed to investigate effects autologous bone marrow mononuclear (BM-MNC) mesenchymal stem (MSCs) via coronary artery on remodeling AMI as well different Methods A total 36 male pigs were enrolled this study, which...
Figure S1. Immunofluorescence staining of α-actinin in NRVMs for identification on day 7 (bar = 30 um). S2. Cx-43 and NC expression. Representative western blotting bands proteins cultured CNH-Col collagen substrates days 3 7, n = 3. Table Summary the electrical conductivity (S/m). (DOCX 343 kb)