Sadahiko Nishizawa

ORCID: 0000-0001-9391-882X
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About
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Research Areas
  • Medical Imaging Techniques and Applications
  • Advanced MRI Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Radiopharmaceutical Chemistry and Applications
  • Cerebrovascular and Carotid Artery Diseases
  • MRI in cancer diagnosis
  • Glioma Diagnosis and Treatment
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Hearing Loss and Rehabilitation
  • Functional Brain Connectivity Studies
  • Lung Cancer Diagnosis and Treatment
  • Intracranial Aneurysms: Treatment and Complications
  • Cancer, Hypoxia, and Metabolism
  • Lanthanide and Transition Metal Complexes
  • Acute Ischemic Stroke Management
  • Neurobiology of Language and Bilingualism
  • Neuroscience and Neuropharmacology Research
  • Cardiac Imaging and Diagnostics
  • Cerebrospinal fluid and hydrocephalus
  • Head and Neck Cancer Studies
  • Medical Imaging and Pathology Studies
  • Advanced Neuroimaging Techniques and Applications
  • Salivary Gland Tumors Diagnosis and Treatment
  • Pituitary Gland Disorders and Treatments
  • Thyroid Cancer Diagnosis and Treatment

Hamamatsu Photonics (Japan)
2004-2022

Hamamatsu Medical Center
2010-2022

Hamamatsu University School of Medicine
2022

Kyoto University
1995-2009

Translational Research Informatics Center (Japan)
2005-2009

University of Fukui
2000-2004

Montreal Neurological Institute and Hospital
1996-2004

Shiga Medical Center for Adults
1999

McGill University
1996-1998

Tohoku University
1995

Brain activity associated with voluntary muscle relaxation was examined by applying event-related functional magnetic resonance imaging (fMRI) technique, which enables us to observe change of fMRI signals a single motor trial. The subject voluntarily relaxed or contracted the right upper limb muscles. Each mode had two conditions; one required joint movement, and other did not. Five axial images covering primary area (M1) supplementary (SMA) were obtained once every second, using an...

10.1523/jneurosci.19-09-03527.1999 article EN cc-by-nc-sa Journal of Neuroscience 1999-05-01

10.1007/s00259-004-1703-x article EN European Journal of Nuclear Medicine and Molecular Imaging 2004-12-14

With a large database, we aimed to evaluate sex-specific distinctive changes in brain glucose metabolism and morphology during normal aging using MRI (18)F-FDG PET.A total of 963 cognitively healthy adults were included this study. All subjects completed medical questionnaire, took the mini-mental state examination, underwent whole-body PET. The MR PET images statistically analyzed 3-dimensional stereotactic surface projection. corrected for whole-brain pixel value identify regions with...

10.2967/jnumed.115.166439 article EN Journal of Nuclear Medicine 2015-11-25

Recently, two methods have been proposed for regional cerebral blood flow (rCBF) quantitation using [ 123 I]iodoamphetamine (IMP) and single-photon emission computed tomography (SPECT). The table look-up (TLU) method has shown to provide both rCBF volume of distribution, V d , images from SPECT scans, while a single-scan autoradiographic (ARG) technique provided fixed assumed . In methods, single sample was referred calibrate the previously determined standard input function present...

10.1097/00004647-199609000-00003 article EN Journal of Cerebral Blood Flow & Metabolism 1996-09-01

In order to validate the use of technetium-99m– d,l-hexamethylpropyleneamine oxime (HM-PAO) as a flow tracer, total 21 cases were studied with single photon emission computerized tomography (SPECT), and compared regional cerebral blood (rCBF) measured by position (PET) using oxygen-15 CO 2 inhalation technique. Although HM-PAO SPECT rCBF PET images showed similar distribution pattern image less contrast between high low activity regions than nonlinear relationship was shown. Based on...

10.1038/jcbfm.1988.36 article EN Journal of Cerebral Blood Flow & Metabolism 1988-12-01

The aim of this study was to survey the 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET) cancer screening program conducted in Japan.The "FDG-PET program" included both FDG-PET and positron with computed (PET/CT) or without other combined tests that were performed for asymptomatic subjects. A total 155,456 subjects who underwent during 2006-2009 analyzed.Of subjects, positive findings suggesting possible noted 16,955 (10.9 %). number cases detected 1,912 (1.23 % screened cases,...

10.1007/s12149-012-0660-x article EN cc-by Annals of Nuclear Medicine 2012-10-19

As 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is becoming a common imaging modality, the number of thyroid incidentalomas identified by FDG-PET (PET incidentaloma) increasing. The purpose this study was to elucidate risk cancer in focal PET incidentaloma healthy subjects relatively younger age as well usefulness repeated FDG-PET. conducted with an observation period three years. A total 1,501 volunteers (mean age, 43.5+/-9.7 years) underwent first from August 2003 July...

10.1507/endocrj.k10e-008 article EN Endocrine Journal 2010-01-01

WE tried to identify the mechanisms directly related syntactic processing in an fMRI experiment using strictly controlled sets of verbal stimuli. In two conditions, center-embedding and left-branching same words were used construct stimulus sentences, while only word order reflecting their structure was different. The subject's task understand relationship among three characters mentioned sentences. A difference activation Broca's area (BA44 45) between conditions found. This result suggests...

10.1097/00001756-199810050-00032 article EN Neuroreport 1998-10-01

Purpose To prospectively evaluate the utility of whole-body cancer screening with multiple modalities including [ 18 F]fluorodeoxyglucose positron emission tomography (FDG-PET) in a healthy population. This report summarizes results first three annual screenings. Participants and Methods A total 1,197 volunteers ≥ 35 years old were enrolled between August 2003 July 2004 offered for 5 subsequent long-term follow-up. Screening included FDG-PET, chest abdominal computed (CT), brain pelvic...

10.1200/jco.2008.18.2238 article EN Journal of Clinical Oncology 2009-03-03

Mitochondrial dysfunction has been implicated in the pathophysiology of autism spectrum disorder (ASD) previous studies postmortem brain or peripheral samples. The authors investigated whether and where mitochondrial occurs living brains individuals with ASD to identify clinical correlates detected dysfunction.This case-control study used positron emission tomography (PET) 2-tert-butyl-4-chloro-5-{6-[2-(2-[18F]fluoroethoxy)-ethoxy]-pyridin-3-ylmethoxy}-2H-pyridazin-3-one ([18F]BCPP-EF), a...

10.1176/appi.ajp.22010014 article EN American Journal of Psychiatry 2022-09-07

To use magnetic resonance (MR) imaging to evaluate the morphologic changes of pituitary gland during development hypothyroidism.Fourteen patients who had undergone thyroidectomy were evaluated before radioactive iodine 131 therapy. In each patient, MR and measurement serum hormone levels performed twice: 5 weeks 131I treatment as "euthyroid state" with thyroid supplementation on day "hypothyroid after a 3-week depletion supplements. Nine healthy volunteers also underwent twice at an interval...

10.1148/radiology.213.2.r99nv02383 article EN Radiology 1999-11-01

We used 15O-labelled water in a PET study to test the efficiency of cochlear implants (Cls) transmitting auditory information brain 10 profoundly deaf subjects. Five were postlingually deaf, and five prelingually deaf. All subjects right-handed. White noise verbal stimuli, delivered through CIs, for cortical activation. Similar tasks performed by six right-handed hearing as control group. In subjects, stimulation activated transverse temporal gyri (primary cortices) mainly on side...

10.1093/brain/119.4.1297 article EN Brain 1996-08-01
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