A5045880853- Dementia and Cognitive Impairment Research
- Health, Medicine and Society
- Aging, Elder Care, and Social Issues
- Health Systems, Economic Evaluations, Quality of Life
- Neurogenetic and Muscular Disorders Research
- Healthcare Systems and Practices
- Health disparities and outcomes
- Alzheimer's disease research and treatments
- Psychoanalysis and Psychopathology Research
- Amyotrophic Lateral Sclerosis Research
- Family and Disability Support Research
- Frailty in Older Adults
- Genetic Neurodegenerative Diseases
- Chronic Disease Management Strategies
- Muscle Physiology and Disorders
- Nutrition and Health in Aging
- Reliability and Agreement in Measurement
- Memory Processes and Influences
- Prion Diseases and Protein Misfolding
- Family Support in Illness
- Sexual function and dysfunction studies
- Geriatric Care and Nursing Homes
- Parkinson's Disease and Spinal Disorders
- Delphi Technique in Research
- Memory and Neural Mechanisms
Université de Reims Champagne-Ardenne
2009-2023
Centre Hospitalier Universitaire de Reims
2006-2023
Hôpital Maison Blanche
2002-2023
Cognition, Santé, Société
2018
Hôpital Boucicaut
2001-2006
Université Lumière Lyon 2
2006
Evaluation of health-related quality life (HRQoL) in patients with Alzheimer's disease (AD) is necessary to ensure optimal management. Several scales for assessing HRQoL AD exist, particular the Quality Life Disease (QoL-AD), which includes an evaluation by caregiver patient's HRQoL. The aim this study was identify factors associated patient, and overall as assessed QoL-AD. Cross-sectional multicenter subjects aged 65 years older, mild moderate AD. scores from QoL-AD were recorded (3 scores,...
Abstract Objective The aim of the study was to examine agreement between patient reports and their proxy (family care provider proxies) on Health Status in a sample patients with dementia. Method Ninety‐nine mild moderate dementia proxies completed 38‐item Nottingham Profile (NHP) questionnaire. Results Completion rates for different NHP dimensions ranged from 78 90% subjects. Inter‐rater subject good physical assessment (ICCs 0.54 0.78 mobility scales). Patient/family concordance five out...
<i>Objective:</i> The study was designed to determine the acceptability, feasibility and validity of measuring quality life in a representative sample dementia patients with generic instrument, Duke Health Profile. <i>Method:</i> French version Profile administered 148 subjects mental disorder according DSM-III-R diagnostic criteria. acceptability employing instrument were determined by refusal rate, type administration, percentage distribution missing data....
Objective: To assess the burden on family carers of persons with muscular dystrophy living in their homes and to determine factors contributing carer burden. Methods: The study included 56 dyads people carers. variables for were compared by logistic regression 2 groups (burden //burden � ). Results: mean age patients was 32.7 years (median 26.7, range 15 65 years) that 51 48, 30 80 years). reported care using Zarit Burden Inventory score 23, 0 57/88). Multivariate analysis produced 3...
The aim of this study was to assess the psychometric properties and transcultural adaptation into French quality-of-life in Alzheimer's disease (QoL-AD).A total 120 patient-proxy pairs were recruited six hospitals one French-speaking Swiss hospital take part study. patients presented mild moderate AD (MMSE > or = 10). QoL-AD administered by an interviewer for self-administered caregiver proxies. Thus, validation enabled feasibility, acceptability, reliability convergent discriminant validity...
Objective: The Dementia Quality of Life (DQoL) and the in Alzheimer's Disease (QoL-AD) are two most widely used dementia-specific QoL instruments world. We aimed to compare psychometric properties these identify which is adapted use geriatric consultations.Methods: To evaluate French language validation DQoL QoL-AD, 123 patients aged 65 years over suffering from AD (Mini Mental State Examination score ≥10) were recruited seven hospitals one Switzerland hospital. comprises 29 items, ranked on...
The inhibitory deficit hypothesis has often been cited as a possible explanation for cognitive changes related to age. aim of this study was develop new procedure evaluating effortful inhibition on the basis comprehension metaphors. Our experiment carried out younger and older adults, in whom we also measured capacity, working memory, processing speed. results show that participants required longer time made more frequent errors rejecting metaphors versus literally false statements....
A qualitative work is conducted to enable later the construction of a health-related quality life (HRQL) questionnaire for patients with slowly-progressive neuromuscular disease (NMD) such as myopathies and muscular dystrophies.The formation focus groups an efficient method perform in-depth exploration aspects HRQL potentially impaired by NMD. Patients were recruited in France 4 NMD reference centers. To ensure adequate representativeness terms severity, three types formed: (1) able walk...
Aim: To determine predictive factors associated with rapid cognitive decline (RCD) in elderly patients suffering from Alzheimer disease (AD). Methods: Patients mild to moderate AD were included. RCD was defined as the loss of at least 3 points on Mini-Mental State Examination (MMSE) over 12 months. Factors identified by logistic regression. Results: Among 123 included, 61 followed up until occurred 46% (<i>n</i> = 28). Polymedication (<i>p</i> &#x3c; 0.0001), fact...
Abstract Objective To identify factors predictive of rapid cognitive decline (RCD) among elderly subjects aged 75 or over suffering from dementia. Methods The analysis concerned 250 patients drawn the ‘Sujet Agé Fragile – Evaluation et Suivi’ (SAFES) cohort, presenting a dementia syndrome at inclusion and followed‐up for least 1 year. RCD was defined as loss 3 points on Mini‐Mental State Examination (MMSE) in follow‐up period 12 months. All underwent standardised geriatric evaluation....
Background:Because cognitive processes decline in the earliest stages of Alzheimer's disease (AD), driving abilities are often affected. The naturalistic approach is relevant to study habits and behaviors normal or critical situations a familiar environment particip ants. Objective:This pilot analyzed in-car video recordings patients with early-stage AD healthy controls, special focus on tactical self-regulation behavior. Methods:Twenty (Diagnosis Statistical Manual Mental Disorders, Fourth...
Background. The level of efficiency implicit memory in Alzheimer's disease remains unclear as previous studies using stem completion tasks have led to contradictory results. Method. present study used target words embedded significant short texts that subjects were required read aloud (i.e. enhance semantic processing). Texts presented two perceptual situations: ‘simple’ (blank spaces delimitating words) and ‘complex’ (spaces filled by ‘8’s). In the phase, patients had write first word came...