A5035835682- Functional Brain Connectivity Studies
- Autism Spectrum Disorder Research
- Attention Deficit Hyperactivity Disorder
- Tactile and Sensory Interactions
- Multisensory perception and integration
- Advanced Neuroimaging Techniques and Applications
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Visual perception and processing mechanisms
- Fetal and Pediatric Neurological Disorders
- Neonatal and fetal brain pathology
- Neurobiology of Language and Bilingualism
- Olfactory and Sensory Function Studies
- Cerebral Palsy and Movement Disorders
- Music Technology and Sound Studies
- Action Observation and Synchronization
- Child Development and Digital Technology
- Advanced MRI Techniques and Applications
- Children's Physical and Motor Development
- Anesthesia and Neurotoxicity Research
- Language, Metaphor, and Cognition
- Face Recognition and Perception
- Advanced Optical Imaging Technologies
- Neuroscience and Music Perception
- Child and Animal Learning Development
San Diego State University
2016-2024
Indiana University Bloomington
2014-2015
Indiana University
2013-2014
National Academy of Sciences
1969
National Academies of Sciences, Engineering, and Medicine
1969
The second iteration of the Autism Brain Imaging Data Exchange (ABIDE II) aims to enhance scope brain connectomics research in Spectrum Disorder (ASD). Consistent with initial ABIDE effort I), that released 1112 datasets 2012, this new multisite open-data resource is an aggregate resting state functional magnetic resonance imaging (MRI) and corresponding structural MRI phenotypic datasets. II includes from additional 487 individuals ASD 557 controls previously collected across 16...
Autism spectrum disorder (ASD) is a complex and prevalent neurodevelopmental characterized by social communicative deficits, as well repetitive behaviors atypical sensitivity to sensory stimulation. Alterations in network connectivity are widely recognized, but their interplay with symptoms remains largely unclear. Here, functional magnetic resonance imaging diagnostic behavioral assessments were used cohort of children adolescents ASD (n = 40) matched typically developing (TD, n 38)...
Autism spectrum disorders (ASD) are pervasive developmental characterized by impairments in language development and social interaction, along with restricted stereotyped behaviors. These behaviors often include atypical responses to sensory stimuli; some children ASD easily overwhelmed stimuli, while others may seem unaware of their environment. Vision audition two modalities important for interactions language, differentially affected ASD. In the present study, 16 adolescents typically...
Resting state fMRI (rsfMRI) is frequently used to study brain function, including in clinical populations. Similarity of blood-oxygen-level-dependent (BOLD) fluctuations during rsfMRI between regions thought reflect intrinsic functional connectivity (FC), potentially due history coactivation. To quantify similarity, studies have almost exclusively relied on Pearson correlation, which assumes linearity and can therefore underestimate FC if the hemodynamic response function differs regionally...
Autism spectrum disorders (ASDs) are neurodevelopmental associated with atypical brain connectivity. Although language abilities vary widely, they impaired or in most children ASDs. Underlying mechanisms, however, not fully understood. The present study examined intrinsic functional connectivity (iFC) of the extended network a cohort 52 and adolescents ASDs (ages 8–18 years), using resting‐state magnetic resonance imaging. We found that, comparison to typically developing peers ( n = 50),...
Autism spectrum disorders (ASDs) are increasingly prevalent neurodevelopmental characterized by sociocommunicative impairments. Growing consensus indicates that neurobehavioral abnormalities require explanation in terms of interconnected networks. Despite theoretical speculations about increased local and reduced distal connectivity, links between functional connectivity have not been systematically investigated ASDs. Specifically, it remains open whether hypothesized overconnectivity may...
Journal Article Neuro-Muscular Tests of Aging in Hiroshima Subjects Get access Dorothy R. Hollingsworth, Hollingsworth Assoc. Prof. Pediatrics 2University Kentucky College MedicineLexington, Ky. 40506. Search for other works by this author on: Oxford Academic PubMed Google Scholar J. William and Chairman 3Department Medicine, University Seymour Bogitch, Bogitch 4Atomic Bomb Casualty Comm., U.S. Marine Corps Air Station, FPO SeattleWash. 98764. Robert Keehn 5National Research Council,...
Individuals with autism spectrum disorder (ASD) frequently present impairments in motor skills (e.g., limb coordination, handwriting and balance), which are observed across the lifespan but remain largely untreated. Many adults ASD may thus experience adverse outcomes aging, when physical decline naturally occurs. The 'hand knob' of sensorimotor cortex is an area that critical for control fingers hands. However, this region has received little attention research, especially after midlife....
Abstract Neuroimaging studies have revealed atypical activation during language and executive tasks in individuals with autism spectrum disorders (ASD). However, the spatiotemporal stages of processing associated these dysfunctions remain poorly understood. Using an anatomically constrained magnetoencephalography approach, we examined event-related theta oscillations a double-duty lexical decision task that combined demands on lexico-semantic functions. Relative to typically developing...
Neuroimaging studies of autism spectrum disorder (ASD) have been predominantly unimodal. While many fMRI reported atypical activity patterns for diverse tasks, the MEG literature in ASD remains comparatively small. Our group recently atypically increased event-related theta power individuals with during lexicosemantic processing. The current multimodal study examined relationship between BOLD signal and anatomically-constrained (aMEG) power. Thirty-three adolescents 23 typically developing...
Individuals with autism spectrum disorders (ASD) vary in their language abilities, associated atypical patterns of brain activity. However, few studies have examined the spatiotemporal profiles lexico-semantic processing ASD, particularly as a function heterogeneity. Thirty-nine high-functioning adolescents ASD and 21 typically developing (TD) peers took part lexical decision task that combined semantic access demands on cognitive control. Spatiotemporal characteristics stages were...
Background/Introduction: Autism spectrum disorder (ASD) is characterized by atypical functional connectivity (FC) within and between distributed brain networks. However, FC findings have often been inconsistent, possibly due to a focus on static rather than dynamics. Lagged analyses aim at evaluating temporal latency, presumably neural propagation, regions. This approach may, therefore, reveal more detailed picture of network organization in ASD traditional methods. Methods: The current...
Abstract Individuals with autism spectrum disorder (ASD) frequently present impairments in motor skills (e.g., limb coordination, handwriting and balance), which are observed across the lifespan but remain largely untreated. Many adults ASD may thus experience adverse outcomes aging, when physical decline naturally occurs. The ‘hand knob’ of sensorimotor cortex is an area that critical for control fingers hands. However, this region has received little attention research, especially after...
Abstract Autism spectrum disorder (ASD) is highly heterogeneous in etiology and clinical presentation. Findings on intrinsic functional connectivity (FC) or task-induced FC ASD have been inconsistent including both over- underconnectivity diverse regional patterns. As patterns change across different cognitive demands, a novel more comprehensive approach to network architecture examine the between rest task states, referred as reconfiguration. This suitable for investigating inefficient that...
Areas of the putative visual cortex are involved in combining multisensory information about object shape. In particular, lateral occipital complex (LOC) is a known region visuohaptic recognition. Relative to adult research, there have been few studies investigating development crossmodal perception and haptic information, fewer still exploring neural substrates this ability. present study, BOLD fMRI was measured children aged 7 8.5 years adults during intramodal (visual-to-visual,...