- Pancreatic and Hepatic Oncology Research
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neuroendocrine Tumor Research Advances
- Gastrointestinal Tumor Research and Treatment
- Maritime Transport Emissions and Efficiency
- Atmospheric chemistry and aerosols
- Pancreatitis Pathology and Treatment
- Metastasis and carcinoma case studies
- Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Vehicle emissions and performance
- Renal cell carcinoma treatment
- Gastrointestinal disorders and treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal Cancer Surgical Treatments
- Peptidase Inhibition and Analysis
- Cancer Research and Treatments
- Esophageal and GI Pathology
- MicroRNA in disease regulation
- Colorectal and Anal Carcinomas
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Crystallization and Solubility Studies
- Cancer and Skin Lesions
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2025
Qingdao University
2025
Qingdao Municipal Hospital
2025
Suzhou University of Science and Technology
2024
Zhejiang A & F University
2024
Molecular Oncology (United States)
2023
Shanxi Medical University
2022-2023
South China University of Technology
2022-2023
State Key Laboratory of Molecular Oncology
2023
Fujian Provincial People's Hospital
2022
Ship activity patterns depicted by the International Comprehensive Ocean−Atmosphere Data Set (ICOADS), Automated Mutual-Assistance Vessel Rescue System (AMVER) data set, and their combination demonstrate different spatial statistical sampling biases. These differences could significantly affect accuracy of ship emissions inventories atmospheric modeling. We (using ICOADS) a method to improve global-proxy representativeness trimming over-reporting vessels that mitigates bias, augment sample...
The waterway network ship traffic, energy, and environment model (STEEM) is applied to geographically characterize energy use emissions for interport movement North America, including the United States, Canada, Mexico. STEEM advances existing approaches by (i) estimating large regions on basis of nearly complete data describing historical movements, attributes, operating profiles individual ships, (ii) solving distances an empirical each pair ports considering draft width constraints, (iii)...
Diabetes has become the second most severe disease to human health. Probiotics are important for maintaining gastrointestinal homeostasis and energy balance, have been demonstrated play positive role in prevention treatment of metabolic syndrome like obesity, inflammation, dyslipidemia hyperglycemia. The objective this study was screen potential anti-diabetic strains vitro evaluate its effects vivo. For section, dipeptidyl peptidase IV inhibitory antioxidant activities 14 candidate...
We apply the global climate model ECHAM5/MESSy1-MADE with detailed aerosol and cloud microphysics to study impact of shipping on tropospheric burdens, clouds, radiation budget for four near-future ship emission policy scenarios year 2012. compare a "No Control" scenario sulfur limits regionally applied reductions. show that, if no control measures are taken, near surface sulfate increases by about 10−20% over main transoceanic routes from 2002 A reduction maximum fuel (S) content allowed...
Aim. To evaluate the clinical risk factors influencing overall survival of patients with duodenal adenocarcinoma after potentially curative resection. Methods. A series 201 primary who underwent surgery from 1999 to 2014 at Chinese Medical Academic Cancer Hospital were studied by retrospective chart review and subsequent telephone follow-up. Results. Resectional was performed in 138 attempt treatment, while 63 treated palliative surgery. Median resectional operation 57 months, whereas that...
AIMTo examine the impact of aging on short-term outcomes following pancreatic resection (PR) in elderly patients. METHODSA retrospective cohort study using prospectively collected data was conducted at China National Cancer Center.Consecutive patients who underwent PR from January
Hepatocellular carcinoma (HCC) has poor prognosis and is usually diagnosed only at an advanced stage. Identification of novel biomarkers critical to early diagnosis better for HCC patients. N6-methyladenosine (m6A) RNA methylation regulators play important roles in the development many tumors. However, m6A writer complex, a key executor modification, not been independently investigated, its specific bioinformatics analysis yet performed HCC. In this study, we used multiple public databases...
Background. Identifying diagnostic and prognostic biomarkers that could be targeted in the therapy of pancreatic cancer is essential. Objective. Investigations were conducted with respect to plasma miRNA (miR-21, miR-210, miR-155, miR-196a, miR-20a, miR-25) expression clinicopathologic factors evaluate value miRNAs ductal adenocarcinoma (PDAC). Methods. Plasma detected by real-time quantitative PCR, association was subsequently performed univariate multivariate analyses. Results. Six...
Background: Phyllodes tumors of the breast are rare fibroepithelial lesions, so relatively little is known about this disease entity. The present study was designed to identify differences in clinical features between benign borderline and malignant phyllodes tumors. Materials Methods: Data from 246 women with treated Cancer Hospital Chinese Academy Medical Sciences 2002 2012 were collected analyzed, including age at presentation, treatment, course, size primary tumor, location, histological...
Background . The prognostic relevance of gastric tumor location has been reported and debated. Our study was conducted to examine the differences in clinicopathological features, factors, overall survival (OS) between patients with proximal cancer (PGC) distal (DGC). Patients Methods PGC or DGC were identified from China National Cancer Center Gastric Database (NCCGCDB) during 1997–2017. Survival analysis performed via Kaplan-Meier estimates Cox proportional hazards models. Results We...
Abstract Objective Accurate delineation of the hippocampal region via magnetic resonance imaging (MRI) is crucial for prevention and early diagnosis neurosystemic diseases. Determining how to accurately quickly delineate hippocampus from MRI results has become a serious issue. In this study, pixel-level semantic segmentation method using 3D-UNet proposed realize automatic brain results. Methods: Two hundred three-dimensional T1-weighted (3D-T1) nongadolinium contrast-enhanced (MR) images...
We model cost-effectiveness of control strategies for reducing SO2 emissions from U.S. foreign commerce ships traveling in existing European or hypothetical West Coast SO(x) Emission Control Areas (SECAs) under international maritime regulations. Variation among marginal costs individual choosing between fuel-switching and aftertreatment reveals cost-saving potential economic incentive instruments. Compared to regulations prescribing low sulfur fuels, a performance-based policy can save up...
Fingerprint matching is the most important step in fingerprint identification. This paper presents new results on alignment and scheme based Delaunay Triangulation approach. In order to compare with other techniques, we develop an efficient global comparisons of minutiae sets singular points fingerprints. Alternative approaches for were implemented showcase advantages proposed algorithm. New experimental provide a compelling evidence better performance higher accuracy rates achieved by triangulation
AIM:To identify clonality and genetic alterations in focal nodular hyperplasia (FNH) the nodules derived from it.METHODS: Twelve FNH lesions were examined.Twelve hepatocellular adenomas (HCAs) 22 carcinomas (HCCs) used as references.Nodules of different types identified isolated by microdissection.An X-chromosome inactivation assay was employed to describe their status.Loss heterozygosity (LOH) detected, using 57 markers, for alterations. RESULTS:Nodules altered hepatocytes (NAH), putative...
To assess prognostic benefits of intraoperative electron beam radiation therapy (IOERT) in patients with nonmetastatic locally advanced pancreatic cancer (LAPC) and evaluate optimal adjuvant treatment after IOERT. A retrospective cohort study using prospectively collected data was conducted at the Cancer Hospital Chinese Academy Medical Sciences, China National Center. Two hundred forty-seven consecutive LAPC who underwent IOERT between January 2008 May 2015 were identified included study....