A5079279144- Vestibular and auditory disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Glaucoma and retinal disorders
- Ear Surgery and Otitis Media
- Facial Nerve Paralysis Treatment and Research
- Ophthalmology and Eye Disorders
- Meningioma and schwannoma management
- Spinal Cord Injury Research
- Allergic Rhinitis and Sensitization
- Head and Neck Cancer Studies
- Brain Metastases and Treatment
- Inflammasome and immune disorders
- Advanced Radiotherapy Techniques
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cystic Fibrosis Research Advances
- Neurofibromatosis and Schwannoma Cases
- Neuroblastoma Research and Treatments
- Nasal Surgery and Airway Studies
- Craniofacial Disorders and Treatments
- Ion Channels and Receptors
- Hearing Loss and Rehabilitation
- Ocular Surface and Contact Lens
- Transcranial Magnetic Stimulation Studies
- Management of metastatic bone disease
- Nerve Injury and Rehabilitation
Konkuk University Medical Center
2020-2025
Seoul National University
2019-2022
Seoul National University Bundang Hospital
2018-2020
Seoul Metropolitan Government
2019
Boramae Medical Center
2019
Sungkyunkwan University
2007-2014
Samsung Medical Center
2014
Korea Institute of Radiological and Medical Sciences
2006-2009
Endotype in chronic rhinosinusitis (CRS) has been established the last decade. However, exact immunologic profile of CRS still controversy because it a considerable heterogeneity. Therefore, we investigated various inflammatory mediators according to different nasal tissues and compared them within same subject.We collected uncinate process mucosa (UP) polyp (NP) from controls, without NP (CRSsNP) with (CRSwNP). Expression levels 28 including T helper (Th) 1, Th2, Th17, proinflammatory...
Gradually progressive sensorineural hearing loss (SNHL) is a prevalent sensory defect. It generally untreatable, making rehabilitation by aid or cochlear implantation the only option. However, SNHL as one of symptoms hereditary autoinflammatory systemic disease cryopyrin-associated periodic syndrome, symptom cochlea-specific form (DFNA34), was suggested to respond IL-1 antagonist (anakinra) therapy, which ameliorates NLRP3 variants-induced over-secretion IL-1β. We analysed genotypic and...
Background/Objectives: Aural toilet using microsuction is a common procedure in ENT clinics, and vertigo frequent complaint during this procedure. This study aimed to investigate the characteristics incidence of microsuction-induced nystagmus based on appearance tympanic membrane (TM). Methods: In 85 patients with various TM appearances, were assessed. Results: Microsuction elicited 95% (81 85) 36% (31 85). The direction was towards ipsilateral ear bowing position contralateral leaning...
Background/Objectives: Aural toilet using microsuction is a common procedure in ENT clinics, and vertigo frequent complaint during this procedure. This study aimed to investigate the characteristics incidence of microsuction-induced nystagmus based on appearance tympanic membrane (TM). Methods: In 85 patients with various TM appearances, were assessed. Results: Microsuction elicited 95% (81 85) 36% (31 85). The direction was towards ipsilateral ear bowing position contralateral leaning...
Meniere's disease is thought to be a disorder of the inner ear function, affected by genetic and environmental factors. Several recent studies have shown that air pollution could affect middle diseases. The purpose this study was investigate relationship between occurrence status in Korea. This used time-stratified case-crossover design. Hospital visit data were collected from Korea National Health Insurance Service-National Sample Cohort (NHIS-NSC) database. Daily for sulfur dioxide (SO2),...
To evaluate the prognostic value of 18F-fluorodeoxyglucose positron-emission tomography (FDG PET) with computed (CT) before and during radiotherapy (RT) in patients head neck cancer.Twenty primary squamous cell carcinoma were enrolled this study, whom 6 had oropharyngeal cancer, 10 hypopharyngeal 4 laryngeal cancer. Fifteen received concurrent cisplatin 2 cetuximab chemotherapy. FDG PET/CT was performed RT 4th week RT. The parameters maximum standardized uptake value, metabolic tumor volume,...
<h3>Importance</h3> Permanent surgical treatment for unilateral vocal fold paralysis (UVFP) should be performed when further neural recovery is improbable. Conservative delay of the procedure may cause unnecessary deterioration patient's quality life. Knowledge natural course UVFP important better management and counseling. <h3>Objective</h3> To evaluate UVFP, focusing on time according to injury level assess optimal timing permanent intervention. <h3>Design, Setting, Participants</h3> This...
With the advancement and successful treatment of metastatic spinal cord disease, newer treatments are needed for long-term survivors recurrent disease. The lack a standardized re-treatment regimen difficulty in delineating tumor margins among patients who have received with metallic fixation conventional radiation two challenges to be faced In these patients, we applied hypofractionated stereotactic radiosurgery by defining margin (18)F-fluorodeoxyglucose (FDG) positron emission tomography...
Abstract Objective To examine the treatment effects of repositioning maneuvers with head turned 45° downwards (Gufoni maneuver) and upwards (Appiani in 25 patients ageotropic horizontal semicircular canal (HSCC) benign paroxysmal positional vertigo (BPPV). Methods Patients were randomly assigned to Gufoni or Appiani maneuvers, their immediate short‐term efficacy was investigated. Results The response successful four 16 who treated maneuver not any nine maneuver. showed spontaneous resolution...
Introduction The aim of the present study was to evaluate characteristics brain injury and assess relationship between them treatment outcomes in patients with traumatic benign paroxysmal positional vertigo (t-BPPV).
There are debates on whether mastoid oscillation has any benefit or harm in treating horizontal semicircular canal (HSCC) cupulolithiasis. The goal of this study was to investigate the therapeutic effects new maneuver using only inertia and gravity compare it with previously reported cupulolith repositioning vibration (CuRM). We enrolled 57 patients diagnosed HSCC Patients were randomly allocated CuRM (briefly, 30° head rotation affected side thereafter bidirectional side-lying) simply...
BACKGROUND Hearing loss (HL) in children may adversely affect their development. HL is more prevalent patients with chronic kidney disease (CKD) than the general population. This study evaluated prevalence of and its underlying diseases childhood-onset CKD. METHODS In this retrospective a tertiary referral center, CKD (stage 2-5, age at onset renal symptom < 18 years) were recruited. We referred to syndromic as cases genetic or diseases, extra-renal anomalies addition RESULTS A total 421...
Hearing loss is a highly penetrant phenotype in NLRP3 (Nod-Like-Receptor-Pyrin containing 3) gene-related autoinflammatory disorders. A recent study revealed potential medical treatment of hearing with anakinra (anti-interleukin 1 receptor antagonist) selected cases. However, for severely aggravated not responsive to anakinra, cochlear implantation (CI) would be the last resort rehabilitation. Outcome CI clearly elucidated yet this emerging type related NLRP3-related disorders, which has...
Abstract This study aimed to investigate the incidence of mastoid effusion on temporal bone magnetic resonance imaging (MRI) in patients with Bell’s palsy (BP) and Ramsay Hunt syndrome (RHS), evaluate usefulness early differential diagnosis between BP RHS. The 3.0 T—temporal MRI, which was conducted within 10 days after onset acute facial nerve palsy, compared 131 33 Findings cavity MRI were classified into three groups as normal mastoid, effusion, sclerotic change, ipsilesional...
Background Dizziness is not a common symptom in the lateral semicircular canal (LSCC) dysplasia, and nystagmus findings has been rarely described LSCC dysplasia.Objective To investigate characteristics of spontaneous positional patients with dysplasia.Methods Patterns twelve who visited our clinic chief complaint dizziness, were investigated.Results dysplasia was observed unilaterally 4, bilaterally 8 patients. Non-rotatory dizziness various onset times most description unilateral caloric...
There have been no reports regarding nystagmus observed immediately after the end of an acute vertiginous attack in patients with Meniere’s disease. The aim this study was to demonstrate positional direction-changing disease, and discuss mechanism that underlies nystagmus. Video-nystagmography recorded two definite who showed during period a vertigo attack. In one patient, video-nystagmographic recording conducted 5 h episode attack, it very weak, persistent geotropic other 23 apogeotropic...
Benign paroxysmal positional vertigo (BPPV) is the most common cause of and nystagmus. Direction-changing nystagmus (DCPN), which refers to change in direction with different head positions, a well-known characteristic horizontal semicircular canal BPPV. The supine roll test commonly used diagnose However, persistent geotropic DCPN observed during this cannot be explained by conventional mechanisms canalolithiasis or cupulolithiasis. concept “light cupula” has been proposed account for...
When air irrigation is used for caloric stimulation in patients with a perforated ear, warm may elicit nystagmus that initially beats the opposite direction of what expected irrigations, which referred to as "caloric inversion". This study aimed investigate disease group inversion appeared who underwent testing and classify patterns inversion. We conducted retrospective review bithermal test results were collected our dizziness clinic between 2005 2022. Caloric was defined when induced by...