Shaohua Gu

ORCID: 0000-0001-9481-2015
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About
Contact & Profiles
Research Areas
  • Neurobiology and Insect Physiology Research
  • Insect and Arachnid Ecology and Behavior
  • RNA modifications and cancer
  • Insect-Plant Interactions and Control
  • Insect Resistance and Genetics
  • Insect and Pesticide Research
  • RNA Research and Splicing
  • Ubiquitin and proteasome pathways
  • Insect Utilization and Effects
  • RNA and protein synthesis mechanisms
  • Insect Pest Control Strategies
  • Cancer-related gene regulation
  • Monoclonal and Polyclonal Antibodies Research
  • Molecular Biology Techniques and Applications
  • ATP Synthase and ATPases Research
  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • vaccines and immunoinformatics approaches
  • interferon and immune responses
  • Immunotherapy and Immune Responses
  • Peptidase Inhibition and Analysis
  • Protein Tyrosine Phosphatases
  • Genetics and Neurodevelopmental Disorders
  • RNA Interference and Gene Delivery
  • Cancer-related Molecular Pathways

Ningbo Center for Disease Control and Prevention
2025

China Agricultural University
2020-2024

Sanya University
2024

State Key Laboratory of Genetic Engineering
2008-2021

Fudan University
2009-2021

Zhejiang University
2021

Sichuan Agricultural University
2021

Dakota State University
2021

North Dakota State University
2021

Peking University
2021

Antennal olfaction is extremely important for insect survival, mediating key behaviors such as host preference, mate choice, and oviposition site selection. Multiple antennal proteins are involved in olfactory signal transduction pathways. Of these, odorant receptors (ORs) ionotropic (IRs) confer specificity on sensory neuron responses. In this study, we identified the gene repertoire of economically agricultural pest moth, Helicoverpa armigera, by assembling adult male female...

10.1371/journal.pone.0048260 article EN cc-by PLoS ONE 2012-10-26

Moths depend on olfactory cues such as sex pheromones to find and recognize mating partners. Pheromone receptors (PRs) binding proteins (PBPs) are thought be associated with signal transduction of pheromonal compounds in peripheral reception. Here six candidate pheromone receptor genes the diamondback moth, Plutella xyllostella were identified cloned. All PR display male-biased expression, which is a typical characteristic receptors. In Xenopus-based functional study situ hybridization,...

10.1371/journal.pone.0062098 article EN cc-by PLoS ONE 2013-04-23

Abstract Background One of the challenges in insect chemical ecology is to understand how pheromones are synthesised, detected and degraded. Genome wide survey by comparative sequencing gene specific expression profiling provide rich resources for this challenge. A. ipsilon a destructive pest many crops further characterization genes involved pheromone biosynthesis transport could offer potential targets disruption their communication crop protection. Results Here we report 454...

10.1186/1471-2164-14-636 article EN cc-by BMC Genomics 2013-09-22

ITP and dITP exist in all cells. is potentially mutagenic, the levels of these nucleotides are controlled by inosine triphosphate pyrophosphatase (EC3.6.1.19). Here we report cloning, expression, characterization a 21.5-kDa human (hITPase), an enzyme whose activity has been reported many animal tissues studied populations but protein sequence not determined before. At optimal pH 10.0, recombinant hITPase hydrolyzed ITP, dITP, xanthosine 5′-triphosphate to their respective monophosphates...

10.1074/jbc.m011084200 article EN cc-by Journal of Biological Chemistry 2001-06-01

Abstract Insect odorant binding proteins (OBPs) are thought to involve in insects’ olfaction perception. In the present study, we identified 38 OBP genes from antennal transcriptomes of Spodoptera litura. Tissue expression profiles analysis revealed that 17 SlitOBP transcripts were uniquely or primarily expressed antennae both sexes, suggesting their putative role chemoreception. The RPKM value seven OBPs ( SlitPBP1-3, SlitGOBP1-2, SlitOBP3 and SlitOBP5 ) highly abundant male female...

10.1038/srep13800 article EN cc-by Scientific Reports 2015-09-08

Abstract Herbivore‐induced terpenes have been reported to function as ecological signals in plant–insect interactions. Here, we showed that insect‐induced cotton volatile blends contained 16 terpenoid compounds with a relatively high level of linalool. The diversity terpene production is derived from large synthase (TPS) gene family. TPS family Gossypium hirsutum and raimondii consist 46 41 members, respectively. Twelve genes ( GhTPS4–15 ) could be isolated, protein expression Escherichia...

10.1111/pce.13088 article EN Plant Cell & Environment 2017-10-18

Insects interact with their environment and respond to the changes in host plant conditions using semiochemicals. Such ecological interactions are facilitated by olfactory sensilla use of recognition proteins. The cotton aphid Aphis gossypii can change its phenotype response conditions. They reproduce mainly as wingless asexual morphs but develop wings find mates or new hosts under influence environmental factors such temperature, nutrition population density. Two groups small soluble...

10.1371/journal.pone.0073524 article EN cc-by PLoS ONE 2013-09-20

Apolygus lucorum (Meyer-Dür) (Hemiptera: Miridae) is one of the most important agricultural pests, with broad host range and cryptic feeding habits in China. Chemosensory behavior plays an role many crucial stages life A. lucorum, such as detection sex pheromone cues during mate pursuit fragrant odorants flowering plant localization. Odorant-binding proteins (OBPs) are involved initial biochemical recognition steps semiochemical perception. In present study, a transcriptomics-based approach...

10.1371/journal.pone.0140562 article EN cc-by PLoS ONE 2015-10-14

Host-seeking, ovipositional behavior and mating of insects are controlled mainly by odor perception through sensory organs such as antennae.Antennal chemoreception is extremely important for insect survival.Several antennal chemosensory receptors involved in mediating the detection insects, especially odorant (ORs) ionotropic (IRs), to ensure specificity olfactory neuron responses.In present study, we identified receptor gene repertoire parasitoid wasp Microplitis mediator, a generalist...

10.7150/ijbs.11786 article EN cc-by-nc International Journal of Biological Sciences 2015-01-01

Recent studies have indicated that the plant volatile methyl benzoate (MB) exhibits significant insecticidal bioactivity against several common insects. However, potential environmental hazards of MB and its safety to non-target organisms is poorly understood. In present study, these characteristics were investigated through laboratory experiments field investigations. The results revealed was highly toxic agricultural pest, fall armyworm Spodoptera frugiperda. Compared with commercial...

10.1016/j.ecoenv.2022.114101 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2022-09-22

Abstract In the insect phylum, relationships between individuals and their environment are often modulated by chemical communication. Odorant binding proteins (OBPs) widely robustly expressed in olfactory organs play a key role chemosensing transporting hydrophobic odorants across sensillum lymph to receptor neuron. this study, novel OBP gene ( AlinOBP1 ) lucerne plant bug, Adelphocoris lineolatus was identified, cloned expressed. Real‐time PCR results indicated that expression level of...

10.1002/arch.20427 article EN Archives of Insect Biochemistry and Physiology 2011-05-03
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