A5073929842- Animal Behavior and Reproduction
- Insect and Arachnid Ecology and Behavior
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Neurobiology and Insect Physiology Research
- Advanced biosensing and bioanalysis techniques
- Liver Disease Diagnosis and Treatment
- Plant and animal studies
- PARP inhibition in cancer therapy
- Biosensors and Analytical Detection
- Advanced Nanomaterials in Catalysis
- Advanced Photocatalysis Techniques
- Ectopic Pregnancy Diagnosis and Management
- Monoclonal and Polyclonal Antibodies Research
- Ovarian cancer diagnosis and treatment
- Gold and Silver Nanoparticles Synthesis and Applications
- HER2/EGFR in Cancer Research
- Nanoparticles: synthesis and applications
- Multiple Myeloma Research and Treatments
- Pregnancy and preeclampsia studies
- Trypanosoma species research and implications
- Protein Degradation and Inhibitors
- Homicide, Infanticide, and Child Abuse
- Toxin Mechanisms and Immunotoxins
- Maternal Mental Health During Pregnancy and Postpartum
University of Copenhagen
2022-2024
Jiangsu University
2018-2024
Second Military Medical University
2024
Wuhan University
2023-2024
Renmin Hospital of Wuhan University
2023-2024
Nanjing Normal University
2016-2022
Credo Reference (United States)
2022
Northwood University
2022
Wuhan College
2022
Shanghai Jiao Tong University
2021
Under near-infrared (NIR) light of 810 nm wavelength for irradiation, a very simple and highly sensitive photoelectrochemical (PEC) biosensing platform has been established using the localized surface plasmon resonance effect Au nanoparticles (NPs) as signal amplification nondestructive analysis living cells. The water-dispersible Ag2S quantum dots (QDs) synthesized by one pot method were employed photoelectrochemically active species, they exhibited excellent PEC properties irradiated with...
By using in situ generation of electron acceptor coupled with heterojunction as dual signal amplification, a simple photoelectrochemical (PEC) bioanalysis platform was designed. The synergic effect between the activities carbon nitride (C3N4) nanosheets and PbS quantum dots (QDs) achieved almost nine-fold photocurrent intensity increment compared C3N4 alone. After G-quadruplex/hemin/Pt nanoparticles (NPs) catalase-like activity toward H2O2 were introduced, oxygen generated acted donor by...
In this work, a novel photoelectrochemical biosensing strategy was designed for cell assay under 630 nm (red light) excitation.
Objective: This study aims to investigate perinatal depression in women who gave birth during the COVID-19 pandemic Wuhan, and evaluate effect of on prevalence. Methods: A cross-sectional investigation was conducted into hospitalized for delivery Hubei Maternity Child Healthcare Hospital from December 31, 2019 March 22, 2020, a period which encompasses entire time frame Wuhan. The Edinburgh Postnatal Depression Scale (EPDS) adopted status. Chi-square test logistic regression model were...
Abstract Ant colonies are higher-level organisms consisting of specialized reproductive and non-reproductive individuals that differentiate early in development, similar to germ–soma segregation bilateral Metazoa. Analogous diverging cell lines, developmental differentiation individual ants has often been considered epigenetic terms but the sets genes determine caste phenotypes throughout larval pupal development remain unknown. Here, we reconstruct trajectories two ant species, Monomorium...
Caste differentiation involves many functional traits that diverge during larval growth and metamorphosis to produce adults irreversibly adapted reproductive division of labor. Investigating developmental is important for general biological understanding has increasingly been explored social phenotypes in parallel from similar genotypes. Here, we use Monomorium pharaonis ants investigate the extent which canalized worker development can be shifted toward gyne (virgin-queen) by juvenile...
Ovarian cancer is one of the most frequent causes death among all gynecologic cancers. Though standard therapy often results in temporary clinical remission, patients suffer from recurrence and metastasis ovarian cancer, which highlights need for developing new therapeutic agents targeting specific molecules. Previous studies have demonstrated that native ligand epidermal growth factor receptor (EGFR) ErbB4, heparin-binding EGF-like (HB-EGF), plays a critical role progression associated with...
Abstract Rationale: It is very difficult to treat patients with placenta previa who underwent pregnancy termination and suffered antenatal massive hemorrhage in the 2nd trimester. Patient concerns: In this study, case 1 was fetal malformation of 18-trisomy syndrome at gestation 19 weeks + 2 days, 22 day, 3 for intrauterine death 27 weeks. All cases were completely previa. Diagnoses: For patients, confirmed by ultrasound examination after hospitalization or Interventions: The mifepristone...
Abstract Ants are one of the most ecologically and evolutionarily successful groups animals exhibit a remarkable degree phenotypic diversity. This success is largely attributed to fact that all ants eusocial live in colonies with reproductive division labor between morphologically distinct queen worker castes. Yet, despite over century studies on caste determination evolution ants, we lack complete ontogenetic series from egg adult for any ant species. We therefore present developmental...
Targeted protein degradation through the lysosomal pathway has attracted increasing attention and expanded scope of degradable proteins. However, endogenous strategies are mainly based on antibodies or nanobodies. Effective small molecule degraders still rather rare. Herein, a new approach, termed peptide-mediated lysosome-targeting chimeras (PSMLTACs), was developed by incorporation ligands with lysosome-sorting NPGY motif containing cell-penetrating peptide. PSMLTACs were successfully...
ABSTRACT Ants are one of the most ecologically and evolutionarily successful groups animals exhibit a remarkable degree phenotypic diversity. This success is largely attributed to fact that all ants eusocial live in colonies with reproductive division labor between morphologically distinct queen worker castes. Yet, despite over century studies on caste determination evolution ants, we lack complete ontogenetic series from egg adult for any ant species. We, therefore, present developmental...
Abstract Background Few studies have focused on cesarean delivery (CD) trends among primipara under the one-child and two-child policies. This study aimed to explore in CD rates during 1995–2019 associated factors with risk. Methods obtained clinical data primiparous mothers newborns from 1995 2019 at a large tertiary hospital Wuhan, China. Trends were calculated using joinpoint regression analysis. The Chi-square tests log-binomial analyses used evaluate associations between primary...
Background: Prenatal bleeding is very dangerous for pregnant women with placenta previa during termination of pregnancy in the mid-trimester. Traditionally, cesarean section or hysterectomy used to stop bleeding. This study aims investigate method mid-trimester previa, especially emergency uterine artery embolization (UAE) combined cervical double balloon (CDB). Methods: A retrospective was conducted based on 261 cases mid-pregnancy our hospital, where 34 were set as observation group, and...
Nonalcoholic fatty liver disease (NAFLD) is a strong stimulant of cardiovascular diseases, affecting one-quarter the world's population. TBC1 domain family member 25 (TBC1D25) regulates development myocardial hypertrophy and cerebral ischemia-reperfusion injury; however, its effect on NAFLD/nonalcoholic steatohepatitis (NASH) has not been reported. In this study, we demonstrated that TBC1D25 expression upregulated in NASH. deficiency aggravated hepatic steatosis, inflammation, fibrosis vitro...
Abstract Rationale: Acute fatty liver of pregnancy (AFLP) is extremely hazardous to pregnant woman in the 3rd trimester pregnancy. AFLP has an insidious onset and nonspecific experimental indicators, which therefore difficult be diagnosed. Patient concerns: Case 1 was transferred our hospital for hypertensive disorders complicating at gestation 38 weeks + 3 days. 2 suspicious fetal heart monitoring response 36 4 prelabor rupture membranes 37 Diagnosis: The diagnosis based on Swansea...
Abstract The current pharmacologic treatment of osteoarthritis (OA) is limited to pain relief medications that may bring obvious side effects, so new ideas need be proposed. Eliminating excess reactive oxygen species (ROS) and maintaining the anabolic catabolic function chondrocytes provide a strategy for OA treatment. Here, we prepared nanoparticles (m@PDA−Q) composed polydopamine (PDA), quercetin modified hyaluronic acid. PDA not only functions as carrier hydrophobic drugs, but also...
The aim of the study was to depict global death burden atrial fibrillation and/or flutter (AFF) between 1990 and 2019 predict this in next decade. We retrieved annual data on cases rates AFF from Global Burden Disease (GBD) Study projected trends for 2020-2029 by developing Bayesian age-period-cohort model. number deaths increased 117,038.00 315,336.80 2019. This is reach 404,593.40 2029. age-standardized mortality (ASMRs) have significantly low- middle-sociodemographic index (SDI) regions,...
Abstract Ant colonies are higher-level organisms consisting of specialized reproductive and non-reproductive individuals that differentiate early in development, similar to germ-soma segregation bilateral Metazoa. Analogous diverging cell lines, developmental differentiation individual ants has often been considered epigenetic terms, but the sets genes determine caste phenotypes throughout larval pupal development remain unknown. Here we reconstruct trajectories two ant species after...