A5044196196- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Organ Donation and Transplantation
- Pancreatic and Hepatic Oncology Research
- Renal Transplantation Outcomes and Treatments
- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Transplantation: Methods and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Abdominal vascular conditions and treatments
- Congenital Anomalies and Fetal Surgery
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Renal cell carcinoma treatment
- Blood transfusion and management
- Acute Kidney Injury Research
- Hepatitis B Virus Studies
- Cancer Genomics and Diagnostics
- Pancreatitis Pathology and Treatment
- Renal and Vascular Pathologies
- Blood donation and transfusion practices
- Neuroendocrine Tumor Research Advances
- Hepatitis C virus research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hemostasis and retained surgical items
University of Southern California
2016-2025
Children's Hospital of Los Angeles
2014-2024
Keck Hospital of USC
2004-2024
Erasmus MC Cancer Institute
2023
Eastern Hepatobiliary Surgery Hospital
2003-2020
Second Military Medical University
2003-2020
Southern California University for Professional Studies
2012-2019
Pancreas Centre (Canada)
2019
University of Arizona
2019
Medtronic (Ireland)
2016
<h3>Objectives</h3> To propose an improvement on the current classification of renal dysfunction in cirrhosis. Clinicians caring for patients with cirrhosis recognize that development is associated significant morbidity and mortality. While most cases are functional nature, developed as a result changes haemodynamics, cardiac function, auto-regulation, there increasing number structural their kidney cause dysfunction. Therefore, need newer to include both diseases. <h3>Design</h3> A working...
To compare conventional low-temperature storage of transplant donor livers [static cold (SCS)] with the organs at physiological body temperature [normothermic machine perfusion (NMP)].
Acute liver failure (ALF) is a critical medical condition defined as the rapid development of hepatic dysfunction. Conventional ultrasound elastography cannot continuously monitor stiffness over course rapidly changing diseases for early detection due to requirement handheld probe. In this study, we introduce wearable bioadhesive (BAUS-E), which can generate acoustic radiation force impulse (ARFI) induce shear waves continuous monitoring modulus changes. BAUS-E contains 128 channels with...
Acute kidney injury (AKI) at the time of liver transplantation (LT) has been associated with increased morbidity and mortality. In patients potentially reversible renal dysfunction, predicting whether there will be sufficient return native function is sometimes difficult. Previous studies have focused mainly on effect severity dysfunction or duration pretransplant dialysis posttransplant outcomes. We performed a retrospective analysis who underwent LT our center after Model for End-Stage...
Consensus recommendations have been published to help better define those patients who would benefit from simultaneous liver–kidney transplantation (SLK). We conducted a survey of transplant centers that perform SLK (n = 88, 65% response rate) determine practice patterns in the United States. The majority (73%) stated they use dialysis duration whereas only 30% acute kidney injury as criterion for determining need SLK. Dialysis >4 weeks was used by 32% centers, >6 37% and >8 centers....
Liver transplantation (LT) for patients with renal dysfunction is frequently complicated by major fluid shifts, acidosis, and electrolyte coagulation abnormalities. Continuous replacement therapy (CRRT) has been previously shown to ameliorate these problems. We describe the safety clinical outcomes of intraoperative hemodialysis (IOHD) during LT a group high Model End-Stage Disease (MELD) scores. performed retrospective study at our institution who underwent IOHD from 2002 2012. Seven...
Fontan-associated liver disease (FALD) has emerged as an important morbidity following surgical palliation of single ventricle congenital heart disease. In this study, non-invasive biomarkers that may be associated with severity FALD were explored.A retrospective cohort paediatric patients post-Fontan who underwent biopsy at a high volume centre was reviewed.Among 106 patients, 66% male and 69% Hispanic. The mean age 14.4 ± 3.5 years, performed 10.8 3.6 years post-Fontan. BMI 20.8 5 kg/m2,...
Background: Although canonical Wnt signaling is known to promote tumorigenesis in pancreatic ductal adenocarcinoma (PDAC), a cancer driven principally by mutant K-Ras, the detailed molecular mechanisms which effector β-catenin regulates such are largely unknown. We have previously demonstrated that β-catenin’s differential usage of Kat3 transcriptional coactivator cyclic AMP-response element binding protein-binding protein (CBP) over its highly homologous p300 increases self-renewal and...
Developing strategies for transfusion-free live donor liver transplantation in Jehovah's Witness patients.Liver is the standard of care patients with end-stage disease. A disproportionate increase transplant candidates and an allocation policy restructuring, favoring advanced disease, have led to longer waiting time increased medical acuity recipients. Consequently, patients, who refuse blood product transfusion, are usually excluded from transplantation. We combined augmentation...