A5063869120- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Advanced MRI Techniques and Applications
- Liver Disease and Transplantation
- Advanced X-ray and CT Imaging
- MRI in cancer diagnosis
- Radiation Dose and Imaging
- Radiomics and Machine Learning in Medical Imaging
- Atomic and Subatomic Physics Research
- Medical Imaging Techniques and Applications
- Liver Diseases and Immunity
- Vascular Malformations and Hemangiomas
- Dental Radiography and Imaging
- Lymphatic Disorders and Treatments
- Pancreatic and Hepatic Oncology Research
- Aortic aneurysm repair treatments
- Epilepsy research and treatment
- AI in cancer detection
- Cardiovascular Issues in Pregnancy
- Non-Destructive Testing Techniques
- Spinal Fractures and Fixation Techniques
- Sarcoma Diagnosis and Treatment
- Abdominal vascular conditions and treatments
- Ultrasound and Hyperthermia Applications
- Artificial Intelligence in Healthcare and Education
University Hospital Bonn
2015-2025
University of Bonn
2015-2023
Abstract Aim of this study was to assess the impact virtual monoenergetic images (VMI) in combination and comparison with iterative metal artifact reduction (IMAR) on hip prosthesis-associated artifacts photon-counting detector CT (PCD-CT). Retrospectively, 33 scans acquired during clinical routine a PCD-CT between 08/2022 09/2022 were analyzed. VMI reconstructed for 100–190 keV without IMAR, compared polychromatic images. Qualitatively, extent assessment adjacent soft tissue rated by two...
Smaller 8-mm diameter transjugular intrahepatic portosystemic shunts (TIPS) appear to be more beneficial than larger 10-mm TIPS stent-grafts, but lack the ability for secondary dilation in cases of clinical ineffectiveness. Underdilated VIATORR® stent grafts (VTS) expand passively, whereas novel VIATORR Controlled Expansion (VCX) do not. This study evaluated impact on survival underdilated VCX compared with VTS patients decompensated cirrhosis.This was a prospective case-control including...
Abstract Aim of this study was to assess the impact virtual monoenergetic images (VMI) on dental implant artifacts in photon-counting detector computed tomography (PCD-CT) compared standard reconstructed polychromatic (PI). 30 scans with extensive (≥ 5 implants) implant-associated were retrospectively analyzed. Scans acquired during clinical routine a PCD-CT. VMI for 100–190 keV (10 steps) and PI. Artifact extent assessment adjacent soft tissue rated using 5-point Likert grading scale...
The aim of this study was to assess the impact an iterative metal artifact reduction (iMAR) algorithm combined with virtual monoenergetic images (VMIs) for in photon-counting detector computed tomography (PCDCT) during interventions.
Abstract Purpose This study investigates how endovascular interventionalists adapt to using a robotic platform, specifically the CorPath GRX Robotic System, and examines influence of prior manual catheterization experience. Materials methods An in-vitro trial was conducted assess adaptation robot-assisted catheter-guided interventions in comparison neurovascular phantom. Three interventional radiologists (beginner: no experience; intermediate: 3 years; expert: 10 years) with varying...
Liver fat quantification on contrast-enhanced photon-counting CT scans was accurate compared with the reference standard MRI proton density fraction.
Abstract Purpose To identify the frequency and association of visceral arterial (VA) stenosis in peripancreatic aneurysms (PPAs) to develop a uniform, more detailed treatment strategy for PPAs case accompanying VA stenosis, as current guidelines do not adequately address this constellation. Materials methods Patients with diagnosed at tertiary care hospital were retrospectively analyzed. In multiple PPAs, aneurysm highest aneurysm-to-vessel ratio (AVR) within celiac-mesenteric collateral...
This study aims to report human performance in the detection of Focal Cortical Dysplasias (FCDs) using an openly available dataset. Additionally, it defines a subset this data as "difficult" test set establish public baseline benchmark against which new methods for automated FCD can be evaluated. The 28 readers with varying levels expertise detecting FCDs was originally analyzed 146 subjects (not all are available), we 85 cases. Performance measured based on overlap between predicted regions...
Purpose Previous studies have demonstrated that nodule volumetry allows for the deduction of imaging-based biomarkers such as volume doubling time, enabling superior discrimination between benign and malignant lesions compared to 2D-based morphological characteristics. The study aimed assess feasibility accuracy in-vivo magnetic resonance imaging (MRI)-based volumetric assessment lung nodules larger than 6 mm, in comparison current gold standard, CT. Materials methods This involved a...
The aim of the study was to assess injection needle positioning for contrast-enhanced MR-lymphangiography (MRL) by ultrasound-guided saline-solution. 80 patients (33 male, mean age 43.1 years) were referred MRL. position assessed Consecutive lymph node distension observed on sonography followed Transpedal MRL performed when no inguinal nodes could be identified. detection rate recorded. MR-lymphangiograms regarding primary (i.e. enhancement draining vessels) and secondary technical success...
Purpose Due to a lack of data, there is an ongoing debate regarding the optimal frontline interventional therapy for unresectable hepatocellular carcinoma (HCC). The aim study compare results transarterial radioembolization (TARE) as first-line and subsequent following prior chemoembolization (TACE) in these patients. Methods A total 83 patients were evaluated, with 38 having undergone at least one TACE session TARE [27 male; mean age 67.2 years; 68.4% stage Barcelona clinic liver cancer...
Objectives Artificial intelligence (AI) is thought to improve lesion detection. However, a lack of knowledge about human performance prevents comparative evaluation AI and an accurate assessment its impact on clinical decision-making. The objective this work quantitatively evaluate the ability humans detect focal cortical dysplasia (FCD), compare it state-of-the-art AI, determine how may aid diagnostics. Materials Methods We prospectively recorded readers in detecting FCDs using single...
Abstract Objectives In patients with advanced liver disease, portal hypertension is an important risk factor, leading to complications such as esophageal variceal bleeding, ascites, and hepatic encephalopathy. This study aimed determine the diagnostic value of T1 T2 mapping extracellular volume fraction (ECV) for non-invasive assessment hypertension. Methods this prospective study, 50 participants (33 indication trans-jugular intrahepatic portosystemic shunt (TIPS) 17 healthy volunteers)...
Abstract Purpose Autoimmune hepatitis (AIH) is an immune-mediated chronic liver disease that leads to severe fibrosis and cirrhosis. The aim of this study was determine the diagnostic value T1 T2 mapping as well extracellular volume fraction (ECV) for non-invasive assessment in AIH patients. Methods In prospective study, 27 patients (age range: 19–77 years) with underwent MRI. relaxation times ECV were quantified by techniques. presence significant (≥ F2) defined magnetic resonance...
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease, characterized by bile duct inflammation and destruction, leading to biliary fibrosis cirrhosis. The purpose of this study was investigate the utility T1 T2 mapping parameters, including extracellular volume fraction (ECV) for non-invasive assessment severity in patients with PSC.In prospective study, PSC diagnosis were consecutively enrolled from January 2019 July 2020 underwent MRI. Besides morphological sequences,...
To investigate the impact of aortic valve calcification and brain morphology on acute peri-procedural cerebrovascular events (CVEs) in patients undergoing transcatheter implantation (TAVI).Aortic stenosis can be assessed with echocardiography. Cerebral magnetic resonance imaging (MRI) depicts quantifies morphological signs hypoperfusion vascular embolism, which is special interest severe stenosis. Furthermore, subjects who undergo TAVI are prone to suffer clinically silent CVEs.A total 119...
Background The prognosis for advanced Hepatocellular carcinoma (HCC)is still very poor. Despite initial usefulness of immune checkpoint inhibitor (PD-1), phase 3 trials failed to show significant benefit PD-1 inhibition with nivolumab or pembrolizumab in the first and second line therapy HCC. Clinical evidence patients heavily pretreated HCC outside clinical is extremely limited. In this study, we analyzed experience HCC.Methods Between May 2016 January 2019 14 were treated at University...
Image-based detection of intralesional fat in focal liver lesions has been established diagnostic guidelines as a feature indicative hepatocellular carcinoma (HCC) and associated with favorable prognosis. Given recent advances MRI-based quantification techniques, we investigated possible relationship between content histologic tumor grade steatotic HCCs.Patients histopathologically confirmed HCC prior MRI proton density fraction (PDFF) mapping were retrospectively identified. Intralesional...
Rationale and objectivesAim of this study was to assess the impact contrast media dose (CMD) reduction on diagnostic quality photon-counting detector CT (PCD-CT) energy-integrating (EID-CT).MethodsCT scans abdominal region with differing CMD acquired in portal venous phase a PCD-CT were included compared EID-CT scans. Diagnostic intensity rated. Additionally, readers had assign reduced or regular CMD. Regions-of-interest (ROIs) placed defined segments vein, inferior vena cava, liver, spleen,...
Abstract We aimed to investigate the diagnostic utility of MRI extracellular volume fraction (ECV) for assessment liver cirrhosis severity as defined by Child–Pugh class. In this retrospective study, 90 patients (68 cirrhotic and 22 controls), who underwent multiparametric MRI, were identified. Hepatic T1 relaxation times ECV assessed. Clinical scores disease calculated. One-way analysis variance (ANOVA) followed Tukey’s multiple comparison test, Spearman’s correlation coefficient, receiver...