A5050122799- Health and Wellbeing Research
- Nutrition and Health in Aging
- Nutrition, Health and Food Behavior
- Health disparities and outcomes
- Frailty in Older Adults
- Diverse Approaches in Healthcare and Education Studies
- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Health Promotion and Cardiovascular Prevention
- Chronic Disease Management Strategies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Esophageal Cancer Research and Treatment
- Blood Pressure and Hypertension Studies
- Liver Disease Diagnosis and Treatment
- Cardiovascular Health and Risk Factors
- Nutritional Studies and Diet
- Cancer, Lipids, and Metabolism
- Mobile Health and mHealth Applications
- Obesity, Physical Activity, Diet
- Genetic Associations and Epidemiology
- Air Quality and Health Impacts
- Chronic Kidney Disease and Diabetes
- Cancer Risks and Factors
- Thyroid Cancer Diagnosis and Treatment
- Primary Care and Health Outcomes
Seoul National University Hospital
2016-2025
New Generation University College
2010-2025
Seoul National University
2016-2025
National University College
2011-2025
Institute on Aging
2022-2024
Advanced Institute of Convergence Technology
2015-2022
Art Institute of Portland
2022
Public Health Department
2022
Sungshin Women's University
2019
Samsung Medical Center
2018
Abstract The underrepresentation of non-Europeans in human genetic studies so far has limited the diversity individuals genomic datasets and led to reduced medical relevance for a large proportion world’s population. Population-specific reference genome as well genome-wide association diverse populations are needed address this issue. Here we describe pilot phase GenomeAsia 100K Project. This includes whole-genome sequencing dataset from 1,739 219 population groups 64 countries across Asia....
Health screening is an important component of health promotion programs, and countries have promoted general targeting the prevention early management common chronic diseases. In Korea, a General Screening Program (GHSP) began with workers in 1950s continuously expanded its target population, currently includes adult population. The main diseases are cerebroand cardiovascular diseases, including hypertension, diabetes mellitus, dyslipidemia, obesity, related behaviors. Other conditions...
Objectives: To determine the relationships between two tests of stepping ability (the maximal step length (MSL) and rapid test (RST)) standard standing balance, gait, mobility, functional impairment in a group at‐risk older adults. Design: Cross‐sectional study. Setting: University‐based laboratory. Participants: One hundred sixty‐seven mildly balance‐impaired adults recruited for balance‐training fall‐reduction program (mean age 78, range 65–90). Measurements: Measures maximally (MSL, to...
The objectives of this study were to develop a coronary heart disease (CHD) risk model among the Korean Heart Study (KHS) population and compare it with Framingham CHD score.A prospective cohort within national insurance system.18 health promotion centres nationwide between 1996 2001 in Korea.268 315 Koreans ages 30 74 years without at baseline.Non-fatal or fatal events 1997 2011. During an 11.6-year median follow-up, 2596 (1903 non-fatal 693 fatal) occurred cohort. optimal was created by...
Lactobacillus gasseri BNR17 is a probiotic strain isolated from human breast milk. Animal studies reported that inhibited increases in body weight and adipose tissue weights. The purpose of this study was to evaluate the antiobesity effects humans. In randomized, double-blind, placebo-controlled trial, 90 volunteers aged 20–75 years with mass index (BMI) 25 35 kg/m2 were randomized receive placebo, low-dose BNR (BNR-L, 109 CFU/day), or high-dose (BNR-H, 1010 CFU/day) for 12 weeks. Body...
Abstract Objective We investigated whether and how perceived social support is associated with depression quality of life among patients various cancer diagnoses. Methods Data were collected from 1930 treated at the National Cancer Center nine regional centers across Korea. The Duke‐UNC functional scale was used to measure support, PHQ‐9 EORTC QLQ‐C30 patients' levels life, respectively. Results Subjects low reported significantly higher depression, lower scores on all scales, three symptom...
The association between low serum testosterone levels, visceral adipose tissue (VAT), and metabolic syndrome is now well known. However, the relationship hepatic steatosis levels has not been extensively studied. Our aim was to investigate of total with nonalcoholic fatty liver disease (NAFLD), adjusting for influence VAT insulin resistance.This study a retrospective observational cross-sectional one healthy Korean men conducted at Seoul National University Hospital Healthcare System Gangnam...
The importance of adherence to antihypertensive treatments for the prevention cardiovascular disease has not been well elucidated. This study evaluated effect medication on specific mortality (ischemic heart [IHD], cerebral hemorrhage, and infarction). Our used data from a 3% sample cohort that was randomly extracted enrollees Korean National Health Insurance. Study subjects were aged ≥20 years, diagnosed with hypertension, started newly prescribed in 2003 2004. Adherence estimated as...
Abstract Objective Cancer patients are more likely to experience depression than the general population. This study aims evaluate possible association between cancer stigma and among patients. Methods As a part of Korean government's program develop comprehensive supportive care, we conducted nationwide survey in 2010 at National Center nine regional centers across Korea. was assessed by using set 12 questions grouped three domains—impossibility recovery, stereotypes patients, social...
The purpose of the Korean Frailty and Aging Cohort Study (KFACS) is to initiate a nationwide, population-based prospective cohort study older adults living in community assess their frailty status explore transitions between states over time Korea.The KFACS multicentre longitudinal with baseline survey conducted from May 2016 November 2017. Each centre recruited participants using quota sampling stratified by age sex. number through 2 years 10 centres was 3014, each site accounting for...
Screening for hepatocellular carcinoma (HCC) is clinically important given that its early detection has remarkable survival benefits. We investigated the possible role of FIB-4, a recently developed noninvasive marker liver fibrosis based on routine laboratory tests, as clinical indicator predicting future HCC among hepatitis B surface antigen (HBsAg) carriers. Our retrospective cohort study involved 986 Korean HBsAg carriers 40 years age or older who visited Seoul National University...
The aim of this study was to identify gender differences in the health status, community service needs, and quality life older adults living alone an urban city South Korea.A cross-sectional descriptive correlational design used. sampled 1023 (≥65 years) S* City, during period from August October 2018. Trained interviewers conducted face-to-face interviews with participants, using UCLA Loneliness Scale, Short Form Geriatric Depression Scale - Korean version, ENRICHD Social Support Instrument...
Abstract This study tried to investigate the effects of number medications and age on antihypertensive medication adherence in a real-world setting using nationwide representative cohort. We obtained data from National Health Insurance Service-National Sample Cohort (NHIS-NSC) Korea, which is sample 2.2% (N = 1,048,061) total population 46,605,433). Patients aged 20 years or older 150,550) who took for at least 1 year were selected. Medication possession ratio (MPR) was used measuring...
Background:The objective of this article is to assess the mental health issues mild condition coronavirus disease 2019 (COVID-19) patients admitted a community treatment center (CTC) in Korea.Methods: A total 107 CTC were included as study population, and their problems including depression (patient questionnaire-9), anxiety (generalized disorder scale-7), post-traumatic stress (PTSD) (PTSD checklist-5) somatic symptoms (by patient questionnaire-15) evaluated every week during stay.The...
High-sensitivity C-reactive protein (hs-CRP) is an important inflammatory marker, and inflammation known to be involved in the initiation progression of cancer. We investigated association between serum hs-CRP levels all-cause mortality, cancer site-specific mortality apparently cancer-free Koreans.A total 33,567 participants who underwent routine check-ups at a single tertiary hospital health-screening center May 1995 December 2006, whose level data were available, included study. Baseline...
To compare the reliability of acoustic radiation force impulse (ARFI) imaging and supersonic shear (SSI) in measurement liver stiffness.This study was approved by institutional review board, written informed consent obtained for all patients. Seventy-nine patients (25 healthy patients, 26 with Child-Pugh class A, 28 B or C) were enrolled analyzed from April 2012 to 2013. In each patient, three abdominal radiologists performed nine measurements hepatic shear-wave speed both ARFI SSI on same...
A pilot randomized trial assessed the feasibility and effectiveness of an intervention combining Smartcare (activity tracker with a smartphone application) financial incentives.A three-arm, open-label controlled design involving traditional education, Smartcare, incentives was involved in this study. The latter group received depending on achievement daily physical activity goals (process incentive) weight loss targets (outcome incentive). Male university students (N = 105) body mass index...
Background: Overweight and obesity, due to a Westernized diet lack of exercise, are serious global problems that negatively affect not only personal health, but national economies as well. To solve these problems, preventative-based approaches should be taken rather than medical treatments after the occurrence disease. The improvement individual life habits, through continuous care, is thus paramount, long-term treatment goal. This study describes effects ubiquitous health care (uHealth...
Elevated neutrophil to lymphocyte ratio (NLR) has been reported as a marker for chronic inflammation, associated with poor prognosis in ischemic stroke patients, but there no study that investigated its association risk. This was conducted investigate elevated NLR an independent risk factor incidence. Our retrospective cohort included 24,708 generally healthy subjects aged 30–75 who received self-referred health screening at Seoul National University Hospital. Data on incidence retrieved...
BackgroundThis study evaluated whether baseline results of the Timed Up and Go (TUG) test is associated with future dementia occurrence.