Xiaoyan Yang

ORCID: 0000-0001-9701-8810
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Electrochemical sensors and biosensors
  • Biosensors and Analytical Detection
  • Electrochemical Analysis and Applications
  • Advanced Nanomaterials in Catalysis
  • Nanoplatforms for cancer theranostics
  • RNA Interference and Gene Delivery
  • Chalcogenide Semiconductor Thin Films
  • Advanced Drug Delivery Systems
  • Computational Drug Discovery Methods
  • Molecular Sensors and Ion Detection
  • Conducting polymers and applications
  • Quantum Dots Synthesis And Properties
  • Nanoparticle-Based Drug Delivery
  • Perovskite Materials and Applications
  • Advanced Battery Materials and Technologies
  • Alzheimer's disease research and treatments
  • Photodynamic Therapy Research Studies
  • Alkaloids: synthesis and pharmacology
  • DNA and Nucleic Acid Chemistry
  • Supramolecular Self-Assembly in Materials
  • Advanced Photocatalysis Techniques
  • Advancements in Transdermal Drug Delivery
  • Healthcare and Venom Research
  • Flavonoids in Medical Research

Qingdao University of Science and Technology
2015-2025

Second Affiliated Hospital of Zhejiang University
2019-2024

Land Consolidation and Rehabilitation Center
2024

Ministry of Natural Resources
2024

Henan University
2022-2024

Chimie Biologique pour le Vivant
2021-2024

ShenZhen People’s Hospital
2024

West China Medical Center of Sichuan University
2020-2023

Wuhan University
2012-2023

Sichuan University
2010-2023

Herein, a donor-acceptor-donor (D-A-D) structured small molecule (DPP-TPA) is designed and synthesized for photoacoustic imaging (PAI) guided photodynamic/photothermal synergistic therapy. In the diketopyrrolopyrrole (DPP) molecule, thiophene group contained to increase intersystem crossing (ISC) ability through heavy atom effect. Simultaneously, triphenylamine (TPA) introduced bathochromic shift absorption as well charge transport capacity enhancement. After formation of nanoparticles (NPs,...

10.1021/acsnano.6b07927 article EN ACS Nano 2016-12-29

In preclinical and clinical research, to destroy cancers, particularly those located in deep tissues, is still a great challenge. Photodynamic therapy photothermal are promising alternative approaches for tissue cancer curing. Black phosphorus (BP)-based nanomaterials, with broad UV-vis near-infrared absorbance excellent effect, have shown potential biomedical applications. Herein, biocompatible therapeutic platform, chlorin e6 (Ce6)-decorated BP nanosheets (NSs), has been developed...

10.1021/acsami.8b00276 article EN ACS Applied Materials & Interfaces 2018-03-22

Abstract In parallel with researches unveiling the nature and mechanism in solid state battery, numbers of investigations have been pursuing methods to stabilize their performance as well reduce cost. Simple preparation earth‐abundant ingredients are preconditions for a electrolyte be suitable scalable production. this work, commercial anode active material, spinel Li 4 Ti 5 O 12 , is introduced first time, which has high ionic conductivity sustain rate charge/discharge considerable...

10.1002/aenm.202201991 article EN Advanced Energy Materials 2022-08-25

In this work, a photoelectrochemical (PEC) sensor for ovarian cancer detection was constructed based on TiO2/poly(5-formylindole) (P5FIn)heterojunction using cascade amplification. The combined of multiple markers instead single mode can improve diagnostic accuracy. photoelectron conversion efficiency and photocurrent response were significantly improved by the reaction detector glutathione (GSH) with cystine. 17β-Estradiol (E2) had negative effect PEC response, reducing signal, ultimately...

10.1021/acs.analchem.4c06302 article EN Analytical Chemistry 2025-03-17

Abstract Gold'n'beads : A chemiluminescence immunoassay for the sensitive and rapid determination of AFP has been developed, employing bromophenol blue as a novel enhancer by taking advantages easy separation magnetic beads signal amplification gold nanoparticles based on sandwich‐type immunoreaction (see scheme). magnified image (CLIA) developed new (CL) enhancer, (BPB), alpha‐fetoprotein (AFP) (MBs) colloidal (AuNPs) modified with HRP‐labeled anti‐AFP antibodies. BPB, chemical indicator,...

10.1002/chem.200801722 article EN Chemistry - A European Journal 2009-03-16

Abstract Synergistic cancer therapy is of great interest for multiple advantages, such as excellent targeting accuracy, low side effects, and enhanced therapeutic efficiency. Herein, a near‐infrared photosensitizer aza‐BODIPY (AB) with high singlet oxygen quantum yield (Φ Δ = 82%) designed synthesized. With Schiff's base obtained from condensation reaction between doxorubicin (DOX) polyethylene glycol‐benzaldehyde (PEG–CHO) the polymer matrix, encapsulated to afford hydrophilic nanoparticles...

10.1002/adhm.201701272 article EN Advanced Healthcare Materials 2018-01-15

An ultrasensitive electrochemiluminescence (ECL) biosensor was proposed based on a closed bipolar electrode (BPE) for the detection of alkaline phosphatase (ALP). For most BPE–ECL biosensors, an effective signal amplification strategy key to enhance sensitivity system. Herein, enzyme catalysis utilized in Au nanoparticles (NPs) were electrodeposited cathode surface ITO improve stability and signal. Compared with previous increased by at least 3 orders magnitude. The showed high specificity...

10.1021/acs.analchem.0c04517 article EN Analytical Chemistry 2020-12-29

Designing and constructing supramolecular photosensitizer nanosystems with highly efficient photodynamic therapy (PDT) is vital in the nanomedical field. Despite recent advances forming well-defined superstructures, relationship between molecular arrangement nanostructures properties has rarely been involved, which crucial for developing stable photosensitizers PDT. In this work, through a microemulsion-assisted self-assembly approach, indium porphyrin (InTPP) was used to fabricate series of...

10.1021/acsnano.3c09399 article EN ACS Nano 2024-01-16

A simple and selective photoelectrochemical (PEC) biosensor was constructed for Hg2+ detection based on zinc phthalocyanine (ZnPc) dye-sensitized CdS using alginate not only as a carrier but also binder. First, photoactive material in situ modified the electrode surface rapid electrodeposition to obtain an initial photocurrent signal. Second, ZnPc loaded amphiphilic micelle then coated onto film via The subsequently enhanced due favorable dye sensitization effect of CdS. Finally,...

10.1021/acsami.1c00215 article EN ACS Applied Materials & Interfaces 2021-03-31

Abstract It is challenging to achieve long‐term stability of perovskite solar cells due the corrosion and diffusion metal electrodes. Integration compact barriers into devices has been recognized as an effective strategy protect absorber electrode. However, difficulty construct a thin layer few nanometers that can delay ion migration impede chemical reactions simultaneously, in which delicate microstructure design stable material plays important role. Herein, ZrN x barrier films with high...

10.1002/adma.202301684 article EN Advanced Materials 2023-04-30

10.1016/j.trac.2008.04.002 article EN TrAC Trends in Analytical Chemistry 2008-04-24

Single-nanoparticle collision electrochemistry (SNCE) has gradually become an attractive analytical method due to its advantages in detection, such as a fast response, low cost, sample consumption, and situ real-time detection of analytes. However, the biological analyte's direct based on SNCE blocking mode problems sensitivity specificity. In this work, biosensor electrocatalytic strategy was used for H7N9 AIV. Nucleic acid aptamers were introduced recognize target virus (H7N9 AIV). After...

10.1021/acs.analchem.2c00913 article EN Analytical Chemistry 2022-06-03
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