A5036135458- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Oral health in cancer treatment
- Facial Trauma and Fracture Management
- Head and Neck Surgical Oncology
- Head and Neck Cancer Studies
- Management of metastatic bone disease
- Bone fractures and treatments
- Reconstructive Surgery and Microvascular Techniques
- Effects of Radiation Exposure
- Congenital Anomalies and Fetal Surgery
- Heterotopic Ossification and Related Conditions
- Digital Imaging in Medicine
- Mesenchymal stem cell research
- dental development and anomalies
- Tracheal and airway disorders
- Obstructive Sleep Apnea Research
- Dental Implant Techniques and Outcomes
- Surgical Sutures and Adhesives
- Cancer Diagnosis and Treatment
- Organ and Tissue Transplantation Research
- Spinal Dysraphism and Malformations
- Spinal Fractures and Fixation Techniques
- Traumatic Ocular and Foreign Body Injuries
- Breast Implant and Reconstruction
University of Michigan
2016-2025
Michigan Medicine
2013-2024
University of Tulsa
2024
Creative Commons
2016-2023
Ann Arbor Center for Independent Living
2014-2023
Cincinnati Children's Hospital Medical Center
2022
National Cancer Institute
2022
National Institute of Arthritis and Musculoskeletal and Skin Diseases
2021-2022
Michigan United
2005-2022
Zero to Three
2021
The superior volume maintenance of membranous over endochondral bone has been shown in several studies and provides the basis for its preferred clinical use as an onlay grafting material craniofacial skeleton. scientific rationale this seeming embryologic advantage, however, never proven. Our hypothesis is that pattern graft resorption primarily determined by a graft's micro-architecture (relative cortical cancellous composition) rather than origin (membranous versus endochondral)....
Heterotopic ossification induced by injuries and burns is mediated signaling through the SMAD pathway can be targeted with topical apyrase.
We have prepared and isolated the peptide fragments coded for by three exons of human β-globin gene, using arginine-specific protease clostripain (EC 3.4.22.8). The region encoded central exon (amino acid residues 31-104) contains an arginine at position 40. This site was less susceptible to cleavage than two sites that correspond exon-intron boundaries, fragment approximately equimolar mixture entire fragment, β o 31-104 , somewhat smaller contained within it, 41-104 . bound heme...
Object Chiari malformation (CM) Type I is frequently associated with craniosynostosis. Optimal management of CM in patients craniosynostosis not well-established. The goal this study was to report on a series pediatric both and discuss their management. Methods authors searched the medical records 383 consecutive treated for at single institution over 15-year period identify those CM. They recorded demographic data as well surgical treatment outcomes these patients. When MR imaging...
Background: A multidisciplinary meeting was held from March 4 through 6, 2010, in Atlanta, Georgia, to conceptualize, map out, and operationalize the variables most relevant care of patients with craniosynostosis. In this article, authors highlight development craniofacial neurologic surgery parameters care. Methods: Fifty-two conference attendees, representing a broad range expertise craniosynostosis 16 professional societies, participated working group. Literature expert opinion were used...
Surgical care represents an important source of opioid prescribing and chronic use, but rates prolonged use following pediatric procedures remain unclear. The authors describe the risk factors for new persistent in patients after common cleft operations.The examined claims from Truven Marketscan databases January 1, 2010 to December 31, 2014. included opioid-naive ages 8 25, who underwent 1 10 cleft-related procedures. Patients were considered opioid-naïve if they had no prescription fills...
This study characterizes the surgically treated patient population suffering from orbital floor fractures by use of current data a large series consisting 199 cases taken nonurban setting. Data were gathered through retrospective chart review patients for at University Michigan Health System, collected over 10-year period. regarding demographics, signs and symptoms presentation, cause injury, nature associated facial fractures, ocular nonfacial skeleton trauma collected. In total, there...
Since its first description by Virchow in 1851, craniosynostosis has been known as a potentially serious condition resulting premature fusion of skull sutures. Traditionally, regarded an event that occurs early fetal development, shape at birth is determined the suture or sutures involved. In recent years, different form observed. Patients initially come to attention physicians because they exhibit midface hypoplasia occasionally hypertelorism. The affected individuals all have normal and...
Levi, Benjamin M.D.; Kasten, Steven J. Buchman, R. M.D. Author Information
To demonstrate the pro-osteogenic effect of burn injury on heterotopic bone formation using a novel ossicle in vivo model.Heterotopic ossification (HO), or abnormal soft tissue, is troubling sequela and trauma injuries. The exact mechanism by which influences unknown. aim this study was to develop mouse model formation. We hypothesized that would enhance early vascularization subsequent subcutaneously implanted mesenchymal stem cells.Mouse adipose-derived cells were harvested from C57/BL6...
Despite the widespread use of rigid fixation techniques in craniofacial surgery, there is a paucity studies literature that serve to better define reasons for subsequent removal plates and screws. The current study appears be first attempt assess these issues among broad range surgery patients. Fifty-five patients who underwent hardware following at University Michigan Medical Center between 1989 1995 were retrospectively studied via an in-depth chart review. Common included...
Bone grafts are used for the reconstruction of congenital and acquired deformities facial skeleton and, as such, comprise a vital component craniofacial surgeon's armamentarium. A thorough understanding bone graft physiology factors that affect behavior is therefore essential in developing more intelligent use clinical practice. This article presents review basic grafting along with survey pertinent concepts current research. The responsible survival emphasized.
Object After primary repair of a myelomeningocele or lipomyelomeningocele, patients can present with symptoms secondary tethered cord syndrome (TCS). surgical untethering, small percentage these multiple repeat TCS. In presenting TCS, the role as well expected outcomes untethering are not defined. Methods Eighty-four who underwent spinal after at least 1 were retrospectively evaluated using scaled and subjective outcome measures short-term long-term follow-up visits. Outcomes analyzed for...
Background: Bone regeneration during distraction osteogenesis is intricately associated with an enhanced vascular response. Augmenting this response may offer considerable clinical advantages such as optimizing the quality of regenerate formation, decreasing lengthy consolidation periods, or increasing size and distance. Using deferoxamine, angiogenic transcriptional activator, authors posit that substantial increases in volume beyond normal to mechanical can be quantified micro–computed...