A5031305285- Cancer Genomics and Diagnostics
- Bioinformatics and Genomic Networks
- Plant-Microbe Interactions and Immunity
- Plant Stress Responses and Tolerance
- Evolution and Genetic Dynamics
- Genetics, Bioinformatics, and Biomedical Research
- Insect-Plant Interactions and Control
- Seed Germination and Physiology
- Traumatic Brain Injury and Neurovascular Disturbances
- Nematode management and characterization studies
- Geological and Geophysical Studies
- Geological formations and processes
- Hepatocellular Carcinoma Treatment and Prognosis
- Geological and Geochemical Analysis
- Water resources management and optimization
- Soil Carbon and Nitrogen Dynamics
- Microbial Metabolism and Applications
- Phytochemicals and Medicinal Plants
- Fungal Biology and Applications
- Plant Reproductive Biology
- Antioxidant Activity and Oxidative Stress
- Wastewater Treatment and Reuse
- Acute Ischemic Stroke Management
- Microbial Community Ecology and Physiology
- Genomics and Rare Diseases
University of Łódź
2024
China National Petroleum Corporation (China)
2023
Huazhong Agricultural University
2018-2022
Cancer Research UK Cambridge Center
2021
Genomics (United Kingdom)
2021
Lahore General Hospital
2019
University of Malakand
2018
Kuwait Institute for Scientific Research
2017
Massachusetts General Hospital
2011
Harvard University Press
2011
Admission infarct core lesion size is an important determinant of management and outcome in acute (<9 hours) stroke. Our purposes were to: (1) determine the optimal CT perfusion parameter to define using various postprocessing platforms; (2) establish degree variability threshold values between these different platforms.We evaluated 48 consecutive cases with vessel occlusion admission diffusion-weighted imaging within 3 hours each other. was acquired a "second-generation" 66-second biphasic...
Cotton (Gossypium spp.) yield is reduced by stress. In this study, high temperature (HT) suppressed the expression of jasmonic acid (JA) biosynthesis gene allene oxide cyclase 2 (GhAOC2), reducing JA content and causing male sterility in cotton HT-sensitive line H05. Anther was reversed exogenous application methyl jasmonate (MeJA) to early buds. To elucidate role GhAOC2 identify its putative contribution anther response HT, we created knockout plants using CRISPR/Cas9 system. Ghaoc2 mutant...
Dietary tallow was thermally oxidized at 180°C in an open fryer. The (OT) and unoxidized were characterized for oxidation parameters fatty acid composition using GC-MS. Tallow samples fed to rabbits along with 50, 100, 150 mg/kg/day of ellagic (EA) three weeks. Results revealed that the peroxide value (PV) thiobarbituric reactive substances (TBARS) significantly increased, while radical scavenging activity (RSA) decreased oxidation. GC-MS analysis showed eight acids samples, where palmitic...
Sporadic cancer develops from the accrual of somatic mutations. Out all small-scale aberrations in coding regions, 95% are base substitutions, with 90% being missense While multiple studies focused on importance this mutation type, a machine learning method based number protein–protein interactions (PPIs) has not been fully explored. This study aims to develop an improved computational for driver identification, validation and evaluation (DRIVE), which is compared other methods assessing its...
Persistent viral infections, ageing and inflammatory syndromes induce the accumulation of senescent human T cells. However mechanism that regulates function these end-stage cells is unclear. Human CD8+ effector memory re-express CD45RA (CD27-CD45RA+; EMRA) express surface KLRG-1 CD57, exhibit reduced replicative capacity telomerase activation, decreased survival high expression nuclear gH2AX after cell receptor (TCR) activation. We investigated involvement p38 MAP kinase signalling in...
Abstract Wolfiporia cocos, a versatile fungus acclaimed for its nutritional and therapeutic benefits in Traditional Chinese Medicine, holds immense potential pharmaceutical industrial applications. In this study, we aimed to optimize liquid fermentation techniques culture medium composition maximize mycelial biomass (MB) yield, pachymic acid (PA) concentration, overall PA production. Additionally, investigated the molecular basis of our findings by quantifying expression levels genes...
The majority of cancer treatments end in failure due to Intra-Tumor Heterogeneity (ITH). ITH is represented by clonal evolution where different sub-clones compete with each other for resources under conditions Darwinian natural selection. Predicting the growth these within a tumour among key challenges modern research. tumor behavior enables creation risk profiles patients and optimisation their treatment therapeutically targeting more likely grow. Current research efforts this space are...
Identifying the mutations that drive cancer growth is key in clinical decision making and precision oncology. As driver confer selective advantage thus have an increased likelihood of occurrence, frequency-based statistical models are currently favoured. These methods not suited to rare, low frequency, mutations. The alternative approach address this through functional-impact scores, however using highly prone false positives. In paper, we propose a novel combination method for mutation...