A5042276109- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoplatforms for cancer theranostics
- Magnetic and transport properties of perovskites and related materials
- Advanced biosensing and bioanalysis techniques
- Fluoride Effects and Removal
- Advanced Nanomaterials in Catalysis
- Nanocluster Synthesis and Applications
- Crystallography and molecular interactions
- Luminescence and Fluorescent Materials
- High Entropy Alloys Studies
- Electrospun Nanofibers in Biomedical Applications
- Cancer-related molecular mechanisms research
- Biosensors and Analytical Detection
- Orbital Angular Momentum in Optics
- Shape Memory Alloy Transformations
- Luminescence Properties of Advanced Materials
- Bone and Dental Protein Studies
- Quantum Dots Synthesis And Properties
- Plasmonic and Surface Plasmon Research
- Extracellular vesicles in disease
- Molecular Sensors and Ion Detection
- Bone Tissue Engineering Materials
- Natural product bioactivities and synthesis
Shanghai University of Medicine and Health Sciences
2025
Army Medical University
2022-2025
Affiliated Hospital of Southwest Medical University
2025
Zhejiang University
2025
Lanzhou University Second Hospital
2024
Guangdong University of Technology
2022-2024
Tianjin University
2024
Xi’an Children’s Hospital
2024
Jiangsu University
2024
Lanzhou University
2024
Methicillin-resistant Staphylococcus aureus (MRSA) causes osteomyelitis (OM), which seriously threatens public health due to its antimicrobial resistance. To increase the sensitivity of antibiotics and eradicate intracellular bacteria, a Zn2+ vancomycin (Van) codelivered nanotherapeutic (named Man-Zn2+/Van NPs) was fabricated characterized via mannose (Man) modification. NPs exhibit significant inhibitory activity against extra- MRSA obviously decrease minimum concentration Van. can be...
The development of novel nanomaterials with well-controlled morphologies/structures to achieve excellent activities/sensitivities in surface-enhanced Raman scattering (SERS) is crucial advancing the high-performance SERS detections chemical and biological species. In this study, amidoxime surface-functionalized polyacrylonitrile (ASFPAN) nanofibrous membranes surface-decorated silver nanoparticles (Ag NPs) were prepared via technique electrospinning followed by method seed-mediated...
The progress of surface-enhanced Raman scattering (SERS) microscopy and spectroscopy on individual nanostructured materials has been reviewed in this feature article. After a brief introduction nanomaterial SERS, we provide systematic overview the fabrication SERS studies nanoparticulates, nano-junctions hierarchical nano-aggregate. These SERS-active nanomaterials have great potential designing novel highly sensitive substrates for development SERS-based sensing devices with broad range applications.
To date investigations of the dynamics driven colloidal systems have focused on hydrodynamic interactions and often employ optical (laser) tweezers for manipulation. However, fields that provide confinement drive also result in electrodynamic are generally neglected. We address this issue with a detailed study interparticle an ring vortex trap using 150-nm diameter Ag nanoparticles. term resultant electrodynamically interacting nanoparticles matter system. show superior is created by Au...
Bone is one of the prone metastatic sites patients with advanced breast cancer. The "vicious cycle" between osteoclasts and cancer cells plays an essential role in osteolytic bone metastasis from In order to inhibit cancer, NIR-II photoresponsive bone-targeting nanosystems (CuP@PPy-ZOL NPs) are designed synthesized. CuP@PPy-ZOL NPs can trigger photothermal-enhanced Fenton response photodynamic effect enhance photothermal treatment (PTT) thus achieve synergistic anti-tumor effect. Meanwhile,...
The use of silver nanoparticles (Ag NPs) as substrates to obtain satisfactory Raman spectra native proteins is a simple and valuable but challenging process. Herein, the Ag NPs modified with aluminum iodide ions IANPs) were introduced for detection proteins, including acidic BSA (PI 4.7), catalase 5.4), β-casein 4.5), α-casein 4.0), insulin 5.35), basic myoglobin 6.99), lysozyme 11.2). signals all detected significantly improved in comparison reported obtained by using containing Na2SO4, I-,...
Abstract Long noncoding RNAs (lncRNAs) play a crucial role in progression of bladder urothelial carcinoma (BUC). However, the molecular mechanisms behind this have not been elucidated yet. Here, we found that lncRNA MAFG‐AS1 , which is highly expressed BUC, correlated with aggressive characteristics and poor prognosis BUC. We demonstrate can promote BUC proliferation, invasion, metastasis, epithelial‐mesenchymal transition vitro vivo. Mechanistically, direct binding to Hu antigen R (HuR)...
Through designing the composition and processing approach, non-equiatomic (Gd36Tb20Co20Al24)100-xFex (x = 0, 1, 2 3 at.%) high-entropy-metallic-glass (HE-MG) alloy microwires were successfully fabricated by melt-extraction technique. The microstructure magnetocaloric properties of systematically investigated. possess tunable Curie temperatures, i.e. 81–108 K, above typical rare-earth (RE) containing HE-MG reports. high temperatures are attributed to designed composition. Magnetocaloric...
The rapid emergence of drug-resistant bacteria has attracted great attention to exploring advanced antibacterial methods. However, single-modal therapy cannot easily eliminate completely due its low efficacy. Therefore, it is essential achieve multi-modal effectively. Herein, a dual-modal ROS generator was designed based on photosensitive PDA-MnO2@Ce6/liposome (PMCL) nanozymes for synergistic chemo-photodynamic therapy. PMCL adhere through liposome-membrane fusion. Meanwhile, catalyzes...
Manipulating the interaction between inorganic building blocks and polymeric supporting materials is crucial in fabrication optimization of hybrid hierarchical nanostructures. Herein, oxygen plasma etching was used to modify electrospun nanofibers poly(methyl methacrylate) (PMMA) for facilitating growth silver nanoparticles (Ag NPs). The PMMA form overlaid films, surface-decorated with Ag NPs, were explored as active substrates surface-enhanced Raman scattering (SERS). Strong SERS...
Radiotherapy has been used increasingly to treat primary hepatocellular carcinoma. Clinically, the main cause of radiotherapy failure is cellular radioresistance, conferred via glycolytic metabolism. Our previous study demonstrated that Girdin upregulated in carcinoma and promotes invasion metastasis tumor cells. However, whether underlies radio-sensitivity remains unclear. A short hairpin RNA (shRNA) was silence CCDC88A (encoding Girdin), real-time PCR performed determine mRNA expression....
Conjugated organic molecules exhibiting AIE are characterized by the strongly twisted conjugated skeleton, which could provide loose intermolecular stacking and weak π–π interactions in solid state to generate stimuli-responsive materials.
Optical forces acting on metallic nanoparticles can be used to organize mesoscale arrays for various applications. Here, we show that silver deposited as ordered and chains chemically modified substrates using a simple facile optical trapping approach term "optical printing". The patterns preferred separations between resulting from their electrodynamic coupling (i.e., binding) in the electromagnetic field of beam. Centrosymmetric traps readily allow simultaneous deposition nanoparticle...
Gold nanorods (AuNRs) have received tremendous attention recently in the fields of sensing and detection applications due to their unique characteristic surface plasmon resonance. Surface modification AuNRs is a necessary path effectively utilize properties for these applications. In this Article, we focused both on demonstrating recent advances methods functionalization as well use improved performance using various techniques. The main discussed include ligand exchange with assistance...
Abstract Background Previously, several studies have indicated that pediatric IgA nephropathy (IgAN) might be different from adult IgAN, and treatment strategies also between IgAN IgAN. Methods We analyzed two prospective cohorts established by nephrologists, respectively. A comprehensive analysis was performed investigating the difference in clinical pathological characteristics, treatment, prognosis children adults with Results total of 1015 1911 were eligible for analysis. More frequent...