A5029996836- Food Allergy and Anaphylaxis Research
- Ocular Surface and Contact Lens
- Mast cells and histamine
- Nanoplatforms for cancer theranostics
- Advancements in Transdermal Drug Delivery
- Allergic Rhinitis and Sensitization
- Advanced Drug Delivery Systems
- Mitochondrial Function and Pathology
- Pharmacological Effects of Natural Compounds
- Contact Dermatitis and Allergies
- ATP Synthase and ATPases Research
- Platelet Disorders and Treatments
- Polyamine Metabolism and Applications
- Flavonoids in Medical Research
Heilongjiang University of Chinese Medicine
2018-2024
Hyperoside (HYP), a flavonol glycoside compound, has been shown to significantly inhibit the proliferation of malignant tumors. Mitochondria serve as both "energy factories" and "suicide weapon stores" cells. Targeted delivery cytotoxic drugs mitochondria tumor cells vascular is promising strategy improve efficacy chemotherapy.We report novel dual-functional liposome system possessing extracellular charge reversal mitochondrial targeting properties enhance drug accumulation in trigger...
The aim of the present study was to fabricate a
Shuang Huang Lian Injection (SHLI) has been used in China for over 30 years as an effective and widely Chinese herbal prescription to treat acute respiratory infectious. SHLI has, however, caused many severe anaphylactoid reactions. It is important identify the potential components of SHLI. Spectrum-effect relationships were explore potentially components. Based on original formula, honeysuckle, Fructus Forsythiae Radix Scutellariae extracts prepared combined appropriate proportions. The...
To explore the anaphylaxis effect and substances of honeysuckle. Rat peritoneal mast cells (PMC) were separated purified, incubated with compound 48/80 (0.02 g/L), physiological saline honeysuckle extract (120 g/L) at 37 °C for 0, 15, 30, 45 60 min. Degranulation observed by optical microscope transmission electron microscope. Annexin V positive cell rate was detected flow cytometry to reflect degranulation PMC. SD rats supplied intravenous injection a dose 2.25 g/L. After administration,...