Gwendolien Sergeant

ORCID: 0000-0001-9869-3826
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About
Contact & Profiles
Research Areas
  • Cell Image Analysis Techniques
  • Scientific Computing and Data Management
  • Gene expression and cancer classification
  • Gene Regulatory Network Analysis
  • Computational Drug Discovery Methods

Ghent University
2018-2020

VIB-UGent Center for Medical Biotechnology
2018

Cell migration research has become a high-content field. However, the quantitative information encapsulated in these complex and high-dimensional datasets is not fully exploited owing to diversity of experimental protocols non-standardized output formats. In addition, typically are open for reuse. Making data Findable, Accessible, Interoperable, Reusable (FAIR) will enable meta-analysis, integration, mining. Standardized formats controlled vocabularies essential building suitable...

10.1093/gigascience/giaa041 article EN cc-by GigaScience 2020-05-01

Abstract Cell migration research has become a high-content field. However, the quantitative information encapsulated in these complex and high-dimensional datasets is not fully exploited due to diversity of experimental protocols non-standardised output formats. In addition, typically are open for reuse. Making data Findable, Accessible, Interoperable, Reusable (FAIR) will enable meta-analysis, integration, mining. Standardised formats controlled vocabularies essential building suitable...

10.1101/803064 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2019-10-14

In cancer research, cell-based assays are used to assess cell migration and invasion. The major bottleneck is the lack of automated tools visualize analyse large amounts biological dose-response data produced. To address this challenge, we have developed an free software package for analyses, DoRes, which released as add-on freely available open-source tool CellMissy, dedicated management analysis data. DoRes implements non-linear curve fitting functionality into a robust, user-friendly...

10.1093/bioinformatics/bty634 article EN cc-by Bioinformatics 2018-07-24
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