A5092135622- Bacterial Infections and Vaccines
- Pneumonia and Respiratory Infections
- Neonatal Respiratory Health Research
- Respiratory viral infections research
- Microbial infections and disease research
- Antibiotic Resistance in Bacteria
- Influenza Virus Research Studies
Meningococcal (Neisseria meningitidis) serogroup B (MenB) strain antigens are diverse and a limited number of strains can be evaluated using the human serum bactericidal antibody (hSBA) assay. The genetic Antigen Typing System (gMATS) was developed to predict likelihood coverage for large numbers isolates by 4CMenB vaccine, which includes Neisseria adhesin A (NadA), Neisserial Heparin-Binding (NHBA), factor H-binding protein (fHbp), Porin (PorA). In this study, we characterized whole-genome...
Invasive meningococcal disease (IMD) is a life-threatening caused by serogroups A, B, C, W, X, and Y, of which B W are most common in Argentina. The 4-component serogroup (4CMenB) vaccine contains three purified recombinant protein antigens (Neisseria adhesin A [NadA], factor H binding [fHbp], Neisserial Heparin Binding Antigen [NHBA]) outer membrane vesicles (OMV), derived from the New Zealand epidemic strain Porin 1.4. These present conserved strains that belong to other serogroups. In...