Francesco Paolo Zummo

ORCID: 0000-0001-9872-8574
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About
Contact & Profiles
Research Areas
  • Adipose Tissue and Metabolism
  • Liver Disease Diagnosis and Treatment
  • Gastrointestinal motility and disorders
  • Biochemical effects in animals
  • Antioxidant Activity and Oxidative Stress
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Phytochemicals and Antioxidant Activities
  • Gut microbiota and health
  • Diet and metabolism studies
  • Nutrition and Health in Aging
  • Exercise and Physiological Responses
  • Congenital gastrointestinal and neural anomalies
  • Genomics, phytochemicals, and oxidative stress
  • Muscle metabolism and nutrition
  • Muscle Physiology and Disorders
  • Curcumin's Biomedical Applications

University of Palermo
2022-2025

Metabolic Syndrome (MetS) is an extremely complex disease. A non-balanced diet such as high-fat (HFD) induces metabolic dysfunction that could modify redox homeostasis. We here aimed at exploring homeostasis in male Wistar rats, following 8 weeks of HFD, correlating the eventual modification selected biomarkers be associated with clinical manifestations MetS. Therefore, we parameters relative to both glucose tolerance and lipid altered metabolism, but also oxidative pattern. assessed some...

10.3390/antiox12010089 article EN cc-by Antioxidants 2022-12-30

Dysbiosis, influenced by poor diet or stress, is associated with various systemic diseases. Probiotic supplements are recognized for stabilizing gut microbiota and alleviating gastrointestinal issues, like irritable bowel syndrome (IBS). This study focused on the tryptophan pathways, which important regulation of serotonin levels, host physiology behavior regulation.

10.3390/biology13050296 article EN cc-by Biology 2024-04-25

Probiotics have shown the potential to counteract loss of muscle mass, reduce physical fatigue, and mitigate inflammatory response following intense exercise, although mechanisms by which they work are not very clear. The objective this review is describe main harmful effects alcohol on skeletal provide important strategies based use probiotics. excessive consumption a worldwide problem has been be crucial in progression alcoholic liver disease (ALD), for which, date, only therapy available...

10.3390/biomedicines12020382 article EN cc-by Biomedicines 2024-02-07

Background/Objectives: Recent studies have highlighted the role of gut-muscle axis, suggesting that modulation gut microbiota may indirectly benefit skeletal muscle. This study aimed to evaluate effects Lactobacillus fermentum (L. fermentum) supplementation in a model muscle atrophy induced by chronic ethanol (EtOH) intake, focusing on inflammatory and antioxidant mechanisms. Methods: Sixty 12-month-old female Balb/c mice were divided randomly into three groups (n = 20/group): (1) Ethanol...

10.3390/nu17091550 article EN Nutrients 2025-04-30

Tomato fruits defined as "golden" refer to a food product harvested at an incomplete ripening stage with respect red tomatoes full maturation. The aim of this study is explore the putative influence "golden tomato" (GT) on Metabolic Syndrome (MetS), especially focusing effects redox homeostasis. Firstly, differential chemical properties GT matrix were characterized in terms phytonutrient composition and antioxidant capacities tomato (RT). Later, we assessed biochemical, nutraceutical...

10.3390/antiox12051121 article EN cc-by Antioxidants 2023-05-18
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