A5026058986- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Cardiac pacing and defibrillation studies
- Cardiovascular and exercise physiology
- Cardiac Imaging and Diagnostics
- Cardiovascular Effects of Exercise
- Hemodynamic Monitoring and Therapy
- Birth, Development, and Health
- COVID-19 Clinical Research Studies
- Cardiovascular and Diving-Related Complications
- Venous Thromboembolism Diagnosis and Management
- COVID-19 and healthcare impacts
- Cardiac Valve Diseases and Treatments
- Organ Transplantation Techniques and Outcomes
- Preterm Birth and Chorioamnionitis
- Adipose Tissue and Metabolism
- Cardiac and Coronary Surgery Techniques
- Systemic Sclerosis and Related Diseases
- Anatomy and Medical Technology
- Aortic Disease and Treatment Approaches
- Ultrasound in Clinical Applications
- Augmented Reality Applications
- Cardiovascular Issues in Pregnancy
- Respiratory Support and Mechanisms
- Atrial Fibrillation Management and Outcomes
University of Wisconsin–Madison
2019-2025
Cedars-Sinai Medical Center
2024
UW Health University Hospital
2020-2024
University of Southern California
2015-2018
Children's Hospital of Los Angeles
2015-2016
University of Chicago
2015
Background It is unclear whether the recent increase in number of heart transplants performed annually United States only because higher availability donors and if it affected recipients’ survival. Methods Results We examined characteristics recipients from 2008 to 2012 (n=11 654) 2013 2017 (n=14 556) compared them with 2003 2007 (n=10 869). Cox models 30‐day 1‐year risk death post transplant. From 2017, there was an transplanted hearts donor offers but overall decline ratio available...
BACKGROUND: While tricuspid annular plane systolic excursion (TAPSE) captures the predominant longitudinal motion of right ventricle (RV), it does not account for ventricular morphology and radial changes in various forms pulmonary hypertension. This study aims to both motions by dividing TAPSE RV area assess its clinical significance. METHODS: We performed a retrospective analysis 71 subjects with New York Heart Association class II III dyspnea who underwent echocardiogram invasive...
Abstract Poor recovery pattern of oxygen consumption (V̇O 2 ) post‐exercise is associated with adverse clinical outcomes. However, it remains unknown which component the O pathway (Fick principle) defines this prognostic risk, for example, peripheral extraction, stroke volume, heart rate. Retrospective cohort study included 120 participants (heart failure preserved ejection fraction: HFpEF = 68, pre‐capillary pulmonary hypertensio n 31, non‐cardiac dyspnea 21). Percent metrics were...
Pulmonary vascular distensibility (α) is a marker of the ability pulmonary vasculature to dilate in response increases cardiac output, which protects right ventricle from excessive afterload. α measured with exercise predicts clinical outcomes hypertension (PH) and heart failure. In this study, we aim determine if passive leg raise (PLR) maneuver comparable exercise. Invasive cardiopulmonary testing (iCPET) was performed hemodynamics recorded at three stages: rest, PLR peak Four hemodynamic...
Abstract Background Among subjects with exercise intolerance and suspected early‐stage pulmonary hypertension (PH), early identification of vascular disease (PVD) noninvasive methods is essential for prompt PH management. Hypothesis Rest gas exchange parameters (minute ventilation to carbon dioxide production ratio: V E / CO 2 end‐tidal dioxide: ETCO ) can identify PVD in PH. Methods We conducted a retrospective review 55 (per echocardiogram), undergoing invasive hemodynamics cardiopulmonary...
Abstract Deep phenotyping of pulmonary hypertension (PH) with multimodal diagnostic exercise interventions can lead to early focused therapeutic interventions. Herein, we report methods simultaneously assess impedance, differential biventricular myocardial strain, and right ventricular:pulmonary arterial (RV:PA) uncoupling during exercise, which pilot in subjects suspected PH. As proof-of-concept, show that four different diagnoses [pulmonary (PAH); chronic thromboembolic disease (CTEPH); PH...
Journal Article Accepted manuscript Patterns of Late Gadolinium Enhancement in Myosin-binding Protein C3 (MYBPC3)-related Dilated Cardiomyopathy: Imitating the Imitator Get access Alan C Kwan, MD, MD Cedars-Sinai Medical Center, Departments Imaging and Cardiology C. Kwan:Alan.kwan@cshs.org 127 S. San Vicente Blvd AHSP A3600 Los Angeles, CA 90048 https://orcid.org/0000-0002-4393-1011 Search for other works by this author on: Oxford Academic PubMed Google Scholar Naga Dharmavaram, Orit...
Incidental arterial calcification (Ca) on low-dose computed tomography (CT) prior to liver transplant (LT) may help identify those at risk for obstructive coronary artery disease (CAD). A single-center retrospective study of 358 consecutive patients who had undergone LT was performed. Of the 296 met inclusion criteria, 193 (65.2%) CT Ca. Aortic Ca seen in 116 (39.2%), 141 (47.6%), and peripheral 8 (2.7%). Patients with were assigned ordinal scores classified as mild, moderate, severe....
Right ventricular (RV) dilation has been used to predict adverse outcomes in acute pulmonary conditions. It categorize the severity of novel coronavirus infection (COVID-19) infection. Our study aimed use chest CT-angiogram (CTA) assess if increased RV dilation, quantified as an RV:LV (left ventricle) ratio, is associated with COVID-19 infection, and it occurs out proportion lung parenchymal disease.We reviewed clinical, laboratory, CTA findings patients (n = 100), two control groups: normal...