- Nanoparticles: synthesis and applications
- Collagen: Extraction and Characterization
- Graphene and Nanomaterials Applications
- Nanoparticle-Based Drug Delivery
- Electrospun Nanofibers in Biomedical Applications
- Wound Healing and Treatments
- Nanomaterials for catalytic reactions
- Environmental Toxicology and Ecotoxicology
- Antimicrobial agents and applications
- Mesoporous Materials and Catalysis
- Adsorption and biosorption for pollutant removal
- Electrohydrodynamics and Fluid Dynamics
- Bacterial biofilms and quorum sensing
- Membrane Separation Technologies
- Pharmaceutical and Antibiotic Environmental Impacts
- Consumer Attitudes and Food Labeling
- Advanced Cellulose Research Studies
- Endodontics and Root Canal Treatments
- Aquaculture disease management and microbiota
- Pickering emulsions and particle stabilization
- Legionella and Acanthamoeba research
- Microfluidic and Capillary Electrophoresis Applications
- Micro and Nano Robotics
- Silk-based biomaterials and applications
- Academic Research in Diverse Fields
Universitatea Națională de Știință și Tehnologie Politehnica București
2016-2024
As it is used in all aspects of human life, water has become more and polluted. For the past few decades, researchers scientists have focused on developing innovative composite adsorbent membranes for purification. The purpose this research was to synthesize a novel membrane removal toxic pollutants (namely heavy metals, antibiotics microorganisms). as-synthesized chitosan/TiO2 were successfully prepared through simple casting method. TiO2 nanoparticle concentration from kept low, at 1% 5%,...
The scope of this article is to develop composite membranes using chitosan (CS) and graphene oxide (GO) as adsorbents for the removal inorganic pollutants such heavy metal ions, particularly Pb2+, from aqueous solutions. GO was obtained by modified Hummers method blended with CS solution. introduction ethylenediaminetetraacetic acid (EDTA) compound CS/GO suspension lead an increased adsorption capacity elimination metals forming stable chelates them. synthesized were examined Fourier...
This study investigates the usage of electrohydrodynamic (EHD)-3D printing for fabrication bacterial cellulose (BC)/polycaprolactone (PCL) patches loaded with different antibiotics (amoxicillin (AMX), ampicillin (AMP), and kanamycin (KAN)) transdermal delivery. The composite demonstrated facilitated drug loading encapsulation efficiency drugs along extended release profiles. Release curves were also subjected to model fitting, it was found that optimally adapted Higuchi square root each...
The current trend in antimicrobial-agent development focuses on the use of natural compounds that limit toxicity conventional drugs and provide a potential solution to antimicrobial resistance crisis. Curcumin represents bioactive compound with well-known antimicrobial, anticancer, antioxidant properties. However, its hydrophobicity considerably limits possibility body administration. Therefore, dextran-coated iron oxide nanoparticles can be used as efficient drug-delivery supports could...
The aim of this study is to decorate a glass surface with silver nanoparticles (AgNPs) and further prove its efficiency in the removal some thio-derivatives—potential pollutants from water. Therefore, grafting glass-based platforms AgNPs will strongly influence their interaction other substances or molecules. most commonly used molecules for platform functionalization/modification are organosilanes. In case, main interest thioalkyl organosilanes because, after silanization, thio (-SH)...
The aim of this work was to obtain an antimicrobial coating (NanoAg) for polyester-nylon wound dressings (WDs) reducing the risk exogenous related infections. as-prepared NanoAg-WDs were characterized by XRD (X-ray Diffraction), SEM (Scanning Electron Microscopy), TEM (Transmission SAED (Selected Area Diffraction) and IRM (InfraRed Microscopy). Biological characterization consisted in vitro evaluation interaction with fibroblast cell cultures vivo biodistribution studies AgNPs on mice...
Since the water pollution problem still affects environmental system and human health, need to develop innovative membranes has become imperious. Lately, researchers have focused on developing novel materials help diminish contamination problem. The aim of present research was obtain adsorbent composite based a biodegradable polymer, alginate, remove toxic pollutants. Of all pollutants, lead chosen due its high toxicity. were successfully obtained through direct casting method. silver...
Development of efficient controlled local release drugs that prevent systemic side effects is a challenge for anti-osteoporotic treatments. Research new bone-regeneration materials high importance. Strontium (Sr) known as an anti-resorptive and anabolic agent useful in treating osteoporosis. In this study, we compared two different types synthesis used obtaining nano hydroxyapatite (HA) Sr-containing (SrHA) bone tissue engineering. Synthesis HA SrHA was performed using co-precipitation...
In the present study, two chelating resins were prepared and used for simultaneous adsorption of toxic metal ions, i.e., Cr3+, Mn2+, Fe3+, Co2+, Ni2+, Cu2+, Zn2+, Cd2+, Pb2+ (MX+). first step, starting with styrene-divinylbenzene resin, a strong basic anion exchanger Amberlite IRA 402(Cl-) agents, tartrazine (TAR) amido black 10B (AB 10B). Key parameters such as contact time, pH, initial concentration, stability evaluated obtained (IRA 402/TAR 402/AB The show excellent in 2M HCl, NaOH, also...
The gut microbiota dysbiosis that often occurs in cancer therapy requires more efficient treatment options to be developed. In this concern, the present research approach is develop drug delivery systems based on magnetite nanoparticles (MNPs) as nanocarriers for bioactive compounds. First, MNPs were synthesized through spraying-assisted coprecipitation method, followed by loading bee pollen or bread extracts and an antitumoral (5-fluorouracil/5-FU). loaded-MNPs morphologically structurally...
Since its first use as a drug delivery system, mesoporous silica has proven to be surprisingly efficient vehicle due porous structure. Unfortunately, most synthesis methods are based on using large amounts of surfactants, which then removed by solvent extraction or heat treatment, leading an undesired environmental impact because the generated by-products. Hence, in present study, we followed material with wormhole-like pore arrangement, two FDA-approved substances templates, namely Tween-20...
This work describes a new synthesis method for core-shell magnetite nanoparticles with secondary silica shell, functionalized linker system (Fe3O4-PABA-SiO2-linker) using microwave-assisted heating technique. The solid nanomaterial was used the nanophase of peptides (Fmoc route) as support. co-precipitation selected to obtain and sol-gel technique coating (MW) procedure. magnetic properties nanoparticle core offer advantage quick easy alternative separation product from reaction mixture,...
Given the demanding use of controlled drug delivery systems, our attention was focused on developing a magnetic film that can be triggered in presence field for both and actuating mechanism micropump biomedical microelectromechanical systems (BioMEMS). Magnetic alginate films were fabricated three steps: co-precipitation iron salts an alkaline environment to obtain magnetite nanoparticles (Fe3O4), mixing obtained with sodium solution containing glycerol as plasticizer folic acid active...
Achieving and maintaining a well-balanced immune system has righteously become an insightful task for the general population even more fundamental goal those affected by immune-related diseases. Since our functions are indispensable in defending body against pathogens, diseases other external attacks, while playing vital role health modulating response, we require on-point grasp of their shortcoming as foundation development functional foods novel nutraceuticals. Seeing that immunoceuticals...
The aim of the present study was to obtain a hydrogel-based film as carrier for sustained and controlled release vancomycin, an antibiotic commonly used in various types infections. Considering high-water solubility vancomycin (>50 mg/mL) aqueous medium underlying exudates, prolonged from MCM-41 sought. work focused on synthesis malic acid coated magnetite (Fe3O4/malic) by co-precipitation, sol-gel method loading with their use alginate films wound dressing. nanoparticles obtained were...
Nutraceuticals are experiencing a high-rise use nowadays, which is incomparable to few years ago, due shift in consumers' peculiarity tendencies regarding the selection of alternatives Western medicine, potential immunity boosters, or gut-health promoters. Nutraceuticals' compositions and actual effects should be proportional their sought-after status, as they perceived middle ground between pharma rigor naturally occurring actives. Therefore, health benefits via nutrition, safe use,...
Numerous studies have reported the possibility of enhancing properties materials by incorporating foreign elements within their crystal lattice. In this context, while magnetite has widely known that been used for various biomedical applications, introduction other metals its structure could prospectively enhance effectiveness. Specifically, zinc and cerium demonstrated potential through significant antioxidant, anticancer, antimicrobial features. Therefore, aim present study was to develop...
An electrospinning method was used to fabricate a bilayer collagen sponge/chitosan (Col/CS) matrix develop new wound healing dressing.The aim of the study improve mechanical properties and antimicrobial activity sponge as medical device.Col/CS subjected detailed analysis by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), Atomic force (AFM), comparative physico-chemical characteristics (swelling ratio hydrolysis properties, enzymolytic Col/CS morphology)...
Fish are able to accumulate by ingestion various contaminants of aquatic environment, with negative consequences on their intestine, being continuously threatened worldwide heavy metals, pesticides and antibiotics resulted from the human activities. Consequently, health other species can be affected eating contaminated fish meat. In this context, our study aimed perform a comparison between changes in intestine samples Carassius gibelio individuals collected different artificial lakes...
The objective of the present study was to evaluate performance ultrafiltration process on recovery collagen solution constituents at laboratory scale, using a tangential flow filtration, with flat regenerated cellulose membrane (5000 Da). Also permeate flows were evaluated along physicochemical characteristics concentrates, permeates and feed solutions. membranes morphological studied by electron microscopy characterized water solutions permeation different pressures. Keywords: collagen,...